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Tae Kyung Kim,Korosh Khalili,Hyun-Jung Jang 대한초음파의학회 2015 ULTRASONOGRAPHY Vol.34 No.4
A successful program for local ablation therapy for hepatocellular carcinoma (HCC) requiresextensive imaging support for diagnosis and localization of HCC, imaging guidance for theablation procedures, and post-treatment monitoring. Contrast-enhanced ultrasonography (CEUS)has several advantages over computed tomography/magnetic resonance imaging (CT/MRI),including real-time imaging capability, sensitive detection of arterial-phase hypervascularity andwashout, no renal excretion, no ionizing radiation, repeatability, excellent patient compliance,and relatively low cost. CEUS is useful for image guidance for isoechoic lesions. While contrastenhancedCT/MRI is the standard method for the diagnosis of HCC and post-ablation monitoring,CEUS is useful when CT/MRI findings are indeterminate or CT/MRI is contraindicated. This articleprovides a practical review of the role of CEUS in imaging algorithms for pre- and post-ablationtherapy for HCC.
양현경,김태경,Peter N. Burns,장현정,Yuko Kono,Korosh Khalili,Stephanie R. Wilson 대한초음파의학회 2019 ULTRASONOGRAPHY Vol.38 No.4
Contrast-enhanced ultrasound (CEUS) is a powerful technique for differentiating focal liver lesions (FLLs) without the risks of potential nephrotoxicity or ionizing radiation. In the diagnostic algorithm for FLLs on CEUS, washout is an important feature, as its presence is highly suggestive of malignancy and its characteristics are useful in distinguishing hepatocellular from nonhepatocellular malignancies. Interpreting washout on CEUS requires an understanding that microbubble contrast agents are strictly intravascular, unlike computed tomography or magnetic resonance imaging contrast agents. This review explains the definition and types of washout on CEUS in accordance with the 2017 version of the CEUS Liver Imaging Reporting and Data System and presents their applications to differential diagnosis with illustrative examples. Additionally, we propose potential mechanisms of rapid washout and describe the washout phenomenon in benign entities.