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Kedong Song,Liying Li,Lili Ji,Siyuan Li,Chunfeng Mu,Yiwei Wang,Tianqing Liu 한국통합생물학회 2016 Animal cells and systems Vol.20 No.5
Fabrication and transplantation of tissue-engineered bones in a rotating wall vessel bioreactor (RWVB) was studied in the present study aiming to repair segmental bone defects. Osteoblasts were transfected with green fluorescent protein prior to seeding on bio-derived porous bone scaffolds at a density of 1 × 106 cells/mL and cultured in an RWVB for one week. For comparison, constructs were also cultured in a static condition. Morphology and structure of fabricated bones were examined using an inverted microscope, scanning electron microscope and histology analysis via hematoxylin–eosin and toluidine blue staining. Moreover, an animal model for repairing segmental bone defects of a Zelanian rabbit was used to assess the efficacy and biosafety of fabricated bones. In conclusion, tissue-engineered bones grew favorably in RWVB. In animal study, a preliminary repair of bone defects was noticed only in the experimental group after 4 weeks of implantation. Using RWVB, the fabricated tissue-engineered bone constructs were approved with better bio-capability in repairing the segmental bone defect.
Electrospun PU/PVP/GO Separator for Li-ion Batteries
Kedong Song,Ping Zhang,Yuting Huang,Fu Xu,Yanhuai Ding 한국섬유공학회 2019 Fibers and polymers Vol.20 No.5
Polyurethane (PU) has been intensively studied as a promising separator material for Li-ion batteries (LIBs). However, poor dimensional stability and low liquid-electrolyte wettability of pure PU separator restrict its application inLIBs. Here polyvinyl pyrrolidone (PVP) and graphene oxide were employed to enhance the thermal stability, mechanicalperformance and liquid-electrolyte compatibility of PU separator. High anodic stability above 5.25 V was reached in PU/PVP/GO separator, fully compatible with the high-voltage cathode materials. The electrochemical characterization indicatesPU/PVP/GO membrane is a promising separator for advanced LIBs.
Fabrication of Aligned PI/GO Nanofibers for Battery Separators
Qiong Tian,Qiuhong Liu,Kedong Song,Yufan Mei,Jinfeng Peng,Jinfeng Peng,Ji Zhou,Yanhuai Ding 한국섬유공학회 2021 Fibers and polymers Vol.22 No.1
Highly aligned polyimide/graphene oxide (PI/GO) nanofibers were fabricated by using the electrospinning method. As a separator for Li-ion batteries, the PI/GO nanofibers show excellent thermal stability, good wettability toward organicliquid electrolytes and superior electrochemical performance compared to raw PI and commercial battery separators. TheGO nanosheets not only greatly enhance the mechanical strength of the PI matrix, but also increase the resistance to Lidendrites.