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      • KCI등재

        Evaluation of Histological Changes in Back Muscle Injuries in Rats over Time

        Koki Abe,Kazuhide Inage,Yoshihiro Sakuma,Sumihisa Orita,Kazuyo Yamauchi,Miyako Suzuki,Go Kubota,Yasuhiro Oikawa,Takeshi Sainoh,Jun Sato,Kazuki Fujimoto,Yasuhiro Shiga,Hirohito Kanamoto,Kazuhisa Takaha 대한척추외과학회 2017 Asian Spine Journal Vol.11 No.1

        Study Design: Animal model study. Purpose: The purpose of this study was to evaluate the histological variation in the injured muscle and production of calcitonin generelated peptide in rats over time. Overview of Literature: Vertebral surgery has been reported to cause atrophy of the back muscles, which may result in pain. However, few reports have described the time series histological variation in the injured muscle and changes in the dominant nerve. Methods: We used 30 male, 8-week-old Sprague-Dawley rats. The right and left sides of the paravertebral muscle were considered as the injured and uninjured sides, respectively. A 115 g weight was dropped from a height of 1 m on the right paravertebral muscle. Hematoxylin and eosin (H&E) staining of the muscle was performed 1–3 weeks after injury for histological evaluation. Fluoro-Gold (FG) was injected into the paravertebral muscle. The L2 dorsal root ganglia on both sides were resected 1, 2, and 3 weeks after injury, and immunohistochemical staining for calcitonin gene-related peptide was performed. Results: H&E staining of the paravertebral muscle showed infiltration of inflammatory cells and the presence of granulation tissue in the injured part on the ipsilateral side 1 week after injury. Muscle atrophy occurred 3 weeks after injury, but was repaired via spontaneous replacement of muscle cells/fibers. In contrast, compared with the uninjured side, the percentage of cells double-labeled with FG and calcitonin gene-related peptide in FG-positive cells in the dorsal root ganglia of the injured side was significantly increased at each time point throughout the study period. Conclusions: These results suggest that sensitization of the dominant nerve in the dorsal root ganglia, which may be caused by cicatrix formation, can protract injured muscle pain. This information may be helpful in elucidating the underlying mechanism of persistent pain after back muscle injury.

      • KCI등재

        Development of Characteristic Internship Program on Engineering Education

        Oka, Tetsuo,Tanabe, Yuji,Abe, Kazuhisa,Narumi, Takatsune,Sato, Takashi,Tsubokawa, Norio,Kaneko, Futao Korean Society for Engineering Education 2014 공학교육연구 Vol.17 No.4

        A practice on learn-by-doing career education programs has been operated in Faculty of Engineering in Niigata University from 2006. The purpose of the activity is reduction of early unemployment which is due to the gaps between the situations which university students would expect in their job hunting processes and those of their practical work places after getting jobs. We developed a novel internship program to let the students notice the practical situations of engineers outside the university. A major part of the program is composed of two different kinds of internships and what we call a career design workshop. The characteristic programs are called "Market Internship" and "Technology Internship". In the activities, they are organically connected with each other. In the paper we refer to one of the unique internship programs "Technology Internship", which is characterized as a longer-term practice than usual. In the course of one-month internship practices, the students obtained deeper understandings and closer relationship to the practical work places of the companies than usual internships which last less than two weeks. The students estimated these unique experiences effective for their job hunting in near future.

      • KCI등재

        Development of Characteristic Internship Program on Engineering Education

        Tetsuo Oka,Yuji Tanabe,Kazuhisa Abe,Takatsune Narumi,Takashi Sato,Norio Tsubokawa,Futao Kaneko 한국공학교육학회 2014 공학교육연구 Vol.17 No.4

        A practice on learn-by-doing career education programs has been operated in Faculty of Engineering in Niigata University from2006. The purpose of the activity is reduction of early unemployment which is due to the gaps between the situations which universitystudents would expect in their job hunting processes and those of their practical work places after getting jobs. We developed anovel internship program to let the students notice the practical situations of engineers outside the university. A major part of theprogram is composed of two different kinds of internships and what we call a career design workshop. The characteristic programsare called “Market Internship” and “Technology Internship”. In the activities, they are organically connected with each other. Inthe paper we refer to one of the unique internship programs “Technology Internship”, which is characterized as a longer-term practicethan usual. In the course of one-month internship practices, the students obtained deeper understandings and closer relationship tothe practical work places of the companies than usual internships which last less than two weeks. The students estimated theseunique experiences effective for their job hunting in near future.

      • KCI등재

        Level Set based Topological Shape Optimization of Phononic Crystals

        김민근,하시모토 히로시,아베 카주히사,조선호,Kim, Min-Geun,Hashimoto, Hiroshi,Abe, Kazuhisa,Cho, Seonho Computational Structural Engineering Institute of 2012 한국전산구조공학회논문집 Vol.25 No.6

        본 논문에서는 레벨셋 방법을 이용하여, 소음을 차단하기 위한 음향 구조물의 형상 최적설계를 수행하였다. 형상 최적설계의 목적은 특정한 각도와 각속도로 입사되는 입사파에 대해서 음향 투과율(acoustic transmittance)이 최소가 되도록 음향 결정의 형상(inclusion shape)을 결정하는 것이다. 음향 결정 구조에서는 음향이 흩어져 있는 결정 구조에 의해서 굴절되기 때문에 결정 모양을 조정함으로써, 음향 거동을 제어할 수 있다. 본 연구에서는 음향 구조물로 결정이 수평방향으로는 주기적으로 무한히 분포하고 수직방향으로는 유한한 층간 구조를 가지고 있는 소음 방어벽(Noise barrier)을 고려한다. 주기적 구조물을 고려하기 때문에 결정의 좌와 우에 Bloch 이론을 적용해 주기적 경계조건을 부과하였고, 소음 방어벽 위와 아래에는 임피던스 행렬(impedance matrix)를 이용하여, 무한 균질 영역과 소음 방어벽 사이의 음파 투과를 모사하였다. 결정의 위상과 형상변화를 묘사하기 위해서 레벨셋 방법(level set method)을 사용하였다. 레벨셋 방법에서는 초기 영역을 고정시킨 상태에서, 레벨셋으로 표현되는 임시적 경계(implicit moving boundary)를 변화시킴으로써 복잡한 형상을 다룰 수 있다. 몇몇 수치적 예제를 통해, 제시된 방법의 적용성을 검증하였다. A topology optimization method for phononic crystals is developed for the design of sound barriers, using the level set approach. Given a frequency and an incident wave to the phononic crystals, an optimal shape of periodic inclusions is found by minimizing the norm of transmittance. In a sound field including scattering bodies, an acoustic wave can be refracted on the obstacle boundaries, which enables to control acoustic performance by taking the shape of inclusions as the design variables. In this research, we consider a layered structure which is composed of inclusions arranged periodically in horizontal direction while finite inclusions are distributed in vertical direction. Due to the periodicity of inclusions, a unit cell can be considered to analyze the wave propagation together with proper boundary conditions which are imposed on the left and right edges of the unit cell using the Bloch theorem. The boundary conditions for the lower and the upper boundaries of unit cell are described by impedance matrices, which represent the transmission of waves between the layered structure and the semi-infinite external media. A level set method is employed to describe the topology and the shape of inclusions. In the level set method, the initial domain is kept fixed and its boundary is represented by an implicit moving boundary embedded in the level set function, which facilitates to handle complicated topological shape changes. Through several numerical examples, the applicability of the proposed method is demonstrated.

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