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Ayami Inoue,Ken Yamaguchi,Yasuhisa Kurata,Ryusuke Murakami,Kaoru Abiko,Junzo Hamanishi,Eiji Kondoh,Tsukasa Baba,Aki Kido,Ikuo Konishi,Noriomi Matsumura 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.5
Objective: Carcinosarcoma of the uterine corpus has a poor prognosis. Although pathologicalnecrosis is a prognostic factor of endometrial cancer, the clinicopathological influences of anunenhanced region observed on magnetic resonance imaging (MRI) are inconclusive. The aimof our study was to determine the clinicobiological impact of the presence of an unenhancedregion on MRI, which can represent necrosis, in uterine carcinosarcoma. Methods: The clinicopathological factors of 29 patients diagnosed with uterinecarcinosarcoma were assessed retrospectively. The percentage of the tumor that wasunenhanced on MRI was determined. The clinicopathological factors related to theunenhanced regions were evaluated. The prognostic significance was assessed using theKaplan-Meier method and Cox regression model. Results: Although the presence of pathological necrosis was not a poor prognosticfactor (p=0.704), unenhanced regions on MRI correlated with poor prognosis when theunenhanced regions in the tumor accounted for more than 10% of the total tumor (p=0.019). The percentage of unenhanced regions was positively correlated with stage (p=0.028;r=0.4691) and related to tumor size (p=0.086; r=0.3749). The Cox regression analysisindicated that the presence of lymph node (LN) metastasis and more than 10% of the tumorbeing unenhanced on MRI were prognostic factors of overall survival in the univariateanalyses (p=0.018 and p=0.047, respectively). Conclusion: The unenhanced region on MRI, which represents pathological necrosis, reflectstumor progression, and semi-quantification of the region is useful to predict the prognosis inpatients with uterine carcinosarcoma.
Optimum and Adjustable Damping Control of Grid-Connected Inverter with an LCL Filter
Toshiji Kato,Kaoru Inoue,Yusuke Akiyama,Koki Ohashi 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6
This paper proposes a simple and general active damping method with good suppression effects by the optimal control principle with the state feedback approach. It may reduce number of sensors by estimations with a state observer. The proposed method can enhance the damping effects by adjustment of control parameters which correspond to a sort of virtual resistors. Its general design method and examples are described. The regulated current error transfer-functions at the oscillation frequency of the filter are suppressed effectively by validation through simulation by SABER and experiment by a DSP-based digital control system.
Upper-Limb Rehabilitation Exercises Using Haptic Device System
Yoshiyuki Takahashi,Takafumi Terade,Kaoru Inoue,Yuko Ito,Hokyoo Lee,Takashi Komeda 한국과학기술원 인간친화 복지 로봇 시스템 연구센터 2003 International Journal of Assistive Robotics and Me Vol.4 No.2
We have applied a haptic device to the rehabilitation tool and made efforts to integrate the motion and sensory therapy, in order to avoid boredom that the patients usually feel. This rehabilitation tool system consists of a haptic device, a display, a computer, and software for training. When the user moves the grip, the haptic device provides a virtual force and it can either assists the movement of the arm or work against it. We have carried out a preliminary experiment with young and middle age group and elderly group. It aims to confirm the functionality of this system and to collect the reference data for the evaluation of the upper-limb disability. The results of our experiment show that the system could be used to evaluate the patient"s ability of upper-limb motion.
Noor Ayuni Che Zakaria,Takashi Komeda,Cheng Yee Low,Fazah Akhtar Hanapiah,Kaoru Inoue 제어로봇시스템학회 2015 제어로봇시스템학회 국제학술대회 논문집 Vol.2015 No.10
The aim of this work is to formulate a spasticity symptoms-oriented model, in terms of its capability to consistently emulate unidirectional and velocity-dependent spasticity symptoms, based on a Modified Tardieu Scale (MTS). Spasticity stiffness can be simulated using two dynamic equations expressing 1) muscle tone catch during passive stretching at different velocities and 2) resistance through Range Of Motion (ROM). Muscle tone is proportionate to velocity; where muscle resistance is constant until reaching a certain angular velocity. Following different Modified Ashworth Scale (MAS) levels, muscle resistance can occur at varying degrees through the ROM. The simulated spasticity of MAS 1+, based on the developed model, shows a strong positive linear correlation coefficient with average r = 0.7414 for fast forearm extension. The derived model will be used to develop new principles of variable stiffness actuation in an upper limb part-task trainer that is able to emulate upper limb spasticity symptoms.