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The Impacts of Intellectual Property Rights on International Trade Flows in ASEAN Countries
Nguyen Khanh Doanh 대구대학교 경제경영연구소 2006 경제경영연구 Vol.4 No.1
This paper aims at analyzing the impact of intellectual property protection on international trade flows, using ASEAN as a case study. The finding of the paper could be summarized as follows. First, IPR protection is an important determinant of international trade flows. Overall, stronger protection of IPRs increases bilateral trade between ASEAN and the rest of the world. Second, IPR protection in the importing countries (the rest of the world) has positive effect on ASEAN's exports, indicating the market expansion effect. When the impacts of IPR protection are allowed to differ across sectors, stronger effects on exports are found in high tech sectors, such as chemicals and transport equipment and machinery. Third, IPR protection in ASEAN countries has negative effect on their imports from the rest of the world, exhibiting the market power effect. When the impacts of IPR protection are allowed to differ across sectors, strong effects on ASEAN's imports are found in such sectors as food and manufactured goods. Implications being derived from this study are summarized as followed. First, industrializing countries with strong imitative capacities tend to experience the market expansion effect as their IPR regimes become stronger, while for developing countries with weak imitative abilities, the effects of stronger IPR protection in these countries on their imports are ambiguous. Second, most industrializing countries are those which should expect the largest adjustment in domestic output and labor as their fringing production activities are replaced progressively by foreign imports.
Nguyen, Khanh Hoang Viet,Dao, Trong Khoa,Nguyen, Hong Duong,Nguyen, Khanh Hai,Nguyen, Thi Quy,Nguyen, Thuy Tien,Nguyen, Thi Mai Phuong,Truong, Nam Hai,Do, Thi Huyen Asian Australasian Association of Animal Productio 2021 Animal Bioscience Vol.34 No.5
Objective: Fibronectin 3 (FN3) and immunoglobulin like modules (Ig) are usually collocated beside modular cellulase catalytic domains. However, very few researches have investigated the role of these modules. In a previous study, we have sequenced and analyzed bacterial metagenomic DNA in Vietnamese goats' rumen and found that cellulase-producing bacteria and cellulase families were dominant. In this study, the properties of modular cellulases and the role of a FN3 in unique endoglucanase belonging to glycosyl hydorlase (GH) family 5 were determined. Methods: Based on Pfam analysis, the cellulases sequences containing FN3, Ig modules were extracted from 297 complete open reading frames (ORFs). The alkaline, thermostability, tertiary structure of deduced enzymes were predicted by AcalPred, TBI software, Phyre2 and Swiss models. Then, whole and truncated forms of a selected gene were expressed in Escherichia coli and purified by His-tag affinity column for assessment of FN3 ability to enhance enzyme activity, solubility and conformation. Results: From 297 complete ORFs coding for cellulases, 148 sequences containing FN3, Ig were identified. Mostly FN3 appeared in 90.9% beta-glucosidases belonging to glycosyl hydrolase family 3 (GH3) and situated downstream of catalytic domains. The Ig was found upstream of 100% endoglucanase GH9. Rarely FN3 was seen to be situated downstream of X domain and upstream of catalytic domain endoglucanase GH5. Whole enzyme (called XFN3GH5 based on modular structure) and truncate forms FN3, XFN3, FN3GH5, GH5 were cloned in pET22b (+) and pET22SUMO to be expressed in single and fusion forms with a small ubiquitin-related modifier partner (S). The FN3, SFN3 increased GH5 solubility in FN3GH5, SFN3GH5. The SFN3 partly served for GH5 conformation in SFN3GH5, increased modules interaction and enzyme-soluble substrate affinity to enhance SXFN3GH5, SFN3GH5 activities in mixtures. Both SFN3 and SXFN3 did not anchor enzyme on filter paper but exfoliate and separate cellulose chains on filter paper for enzyme hydrolysis. Conclusion: Based on these findings, the presence of FN3 module in certain cellulases was confirmed and it assisted for enzyme conformation and activity in both soluble and insoluble substrate.
Khanh, P.N.,Duc, H.V.,Huong, T.T.,Son, N.T.,Ha, V.T.,Van, D.T.,Tai, B.H.,Kim, J.E.,Jo, A.R.,Kim, Y.H.,Cuong, N.M. Elsevier 2016 Fitoterapia Vol.109 No.-
<P>Phytochemical analysis of the leaves and stems of Callistemon citrinus (Curtis) Skeels led to the isolation of two new alkylphloroglucinols, gallomyrtucommulone E and F (1 and 2), along with four other known alkylphloroglucinol derivatives, gallomyrtucommulone A (3), endoperoxide G3 (4), myrtucommulone B (5), callistenone B (6) and five known triterpenoids, induding betulinic acid (7), 3 beta-acetylmorolic acid (8), 3 beta-hydroxy-urs-11-en-13(28)olide (9), diospyrolide (10) and ursolic acid (11). The structures of the natural compounds were determined from the spectroscopic evidences including 1D-/2D-NMR and HR-MS spectrometry. All the isolated compounds were assessed for the effects on the sEH inhibitory activity. The acylphloroglucinols myrtucommulone B (5)/callistenone B (6) (in mixture), and two triterpenoids, ursolic acid (11) and 3 beta-hydroxy-urs-11-en-13(28)-olide (9) displayed strong inhibition of sEH activity, with IC50 values of 0.7, 112 and 24.8 mu M, respectively. (C) 2015 Elsevier B.V. All rights reserved.</P>
Khanh, Nguyen Nguyen,Yoon, Kyung Byung American Chemical Society 2009 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.131 No.40
<P>The ability to rapidly and reproducibly assemble colloidal particles into large (>mm) one- (1D) and two-dimensional (2D) single crystals with perfect control of the particle networking pattern would open a new world rich with high quality novel materials, technologies, and sciences. However, current methods rely on self-assembly of colloidal particles in solution (wet self-assembly), which intrinsically makes the assembly of the colloidal particles into defect-free large 1D and 2D single crystals difficult. We now demonstrate a new paradigm of colloidal particle organization into 1D and 2D single crystals, a process we call 'dry manual assembly on nanolithographically patterned substrates', which enables facile and rapid organization of colloidal particles in dry states into 1D and 2D single crystals in the centimeter or larger scales with a well-defined particle networking pattern. We believe that this novel methodology will serve as a key to open a new era of particle organization.</P>
Non-cooperative interference alignment for multicell multiuser MIMO uplink channels
Khanh Pham,Kyungchun Lee IET 2017 IET COMMUNICATIONS Vol.11 No.5
<P>Linear interference alignment (IA) is considered a promising interference management technique for future cellular networks. However, its application to practical cellular networks still faces many challenges, two of which are the overhead of sharing global channel state information (CSI) and the cost of signalling dimensionality. These two challenges are resolved in this study via a new linear IA scheme that not only prevents global CSI sharing but also keeps the number of signalling dimensions manageable. While making linear IA more applicable, the proposed scheme provides comparable degrees of freedom to the existing IA schemes in symmetric multicell multiuser multiple-input multiple-output (MIMO) uplink channels.</P>
Experimental and numerical study on the failure of sandwich T-joints under pull-off loading
Khanh-Hung Nguyen,Yong-Bin Park,Jin-Hwe Kweon,Jin-Ho Choi,Chang-Won Shul,Myung-Seog Yang,Seung-Moon Jun 한국항공우주학회 2012 International Journal of Aeronautical and Space Sc Vol.13 No.2
In this study, the failure mechanism of sandwich-to-laminate T-joints under pull-off loading was investigated by experiment and the finite element method. A total of 26 T-joint specimens were manufactured and tested in order to investigate the effects of both adhesive thickness (0.4, 2.0, and 4.0 ㎜) and environmental conditions on the failure of the joints. The results showed that failure occurred mainly as intralaminar failure in the first layer of the sandwich face, which was contacted to the paste adhesive. The failure load did not significantly change with increasing adhesive thickness in both RTD (Room Temperature and Dry) and ETW (Elevated Temperature and Wet) conditions. In the case of ETW conditions, however, the failure load increased slightly with an increase in adhesive thickness. The joints tested in ETW conditions had higher failure loads than those tested in RTD conditions. In addition to the experiment, a finite element analysis was also conducted to investigate the failure of the joint. The stress inside the first ply of the sandwich face was of interest because during the experiment, failure always occurred there. The analysis results showed good agreement with the trend of experimental results, except for the case of the smallest adhesive thickness. The highest stress was predicted in the regions where initial failure was observed in the experiment. The maximum stress was almost constant when the adhesive thickness was beyond 2 ㎜.
Asynchronous sampled-data control design of homogeneous Markovian jump systems
Khanh Hieu Nguyen,Sung Hyun Kim(김성현) 제어로봇시스템학회 2021 제어로봇시스템학회 국내학술대회 논문집 Vol.2021 No.6
This paper deals with the problem of asynchronous sampled-data control for continuous-time Markovian jump systems. First, a time-integrated states is accommodated into the augmented vector that can enhance the efficiency of looped-functional methods. Then, the controller gains are derived by solving a set of linear matrix inequalities. Finally, a numerical example is provided to verify the effectiveness of the proposed method.