Antioxidant and Anti-Inflammatory Effects of Rhei Rhizoma and Coptidis Rhizoma Mixture on Reflux Esophagitis in Rats

Kwon, O Jun,Kim, Min Yeong,Shin, Sung Ho,Lee, Ah Reum,Lee, Joo Young,Seo, Bu-il,Shin, Mi-Rae,Choi, Hyun Gyu,Kim, Jeong Ah,Min, Byung Sun,Kim, Gyo-Nam,Noh, Jeong Sook,Rhee, Man Hee,Roh, Seong-Soo Hindawi Publishing Corporation 2016 Evidence-based Complementary and Alternative Medic Vol.2016 No.-

<P>The purpose of this study was to investigate the antioxidant and anti-inflammatory effects of the combined extract of Rhei rhizoma and Coptidis rhizoma (RC-mix) in experimental model of acute reflux esophagitis. The antioxidant activity was assessed by<I> in vitro</I> 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. RC-mix was given at 100, 200, and 400 mg/kg body weight 2 h prior to induction of reflux esophagitis (RE). After 5 h, the effects of RC-mix treated rats were compared with those of normal and control rats. The representative flavonoid contents of RC-mix, such as sennoside A, epiberberine, coptisine, palmatine, and berberine, were detected using HPLC. The elevated esophageal mucosa damage was markedly ameliorated by RC-mix treatment in a dose-dependent manner. Furthermore, the administration of RC-mix reduced the increase of serum reactive oxygen species (ROS) and peroxynitrite (ONOO<SUP>−</SUP>). The improvement of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1) levels were marked in the group given RC-mix. Moreover, the elevation of inflammatory mediators and cytokines by nuclear factor-kappa B (NF-<I>κ</I>B) activation in control rats decreased by RC-mix pretreatment. These results indicate that RC-mix treatment reduces the pathological states of esophagitis<I> via</I> regulating NF-<I>κ</I>B mediated inflammation related to oxidative stress. </P>

펜싱경기의 규칙변경이 전술에 미치는 영향 : 사브르 경기를 중심으로 Focus on fencing sabre

신준호 청주대학교 학술연구소 2005 淸大學術論集 Vol.5 No.-

This study intents to understand how effective changing rules in saber is to tactics of fencers. Rules of sports have been changed and modified for various reasons in own history and it has regarded that these changes and modifications have occurred because of improvement of commercialization, advent of gigantic organizations, overheated vying, and intervention of political authorities. Because modernization and automation of equipment, and commercialization of sport mainly affected to sport, fencing rules also have affected certain effects to athletic tactics causing changes in traditions, and rules and regulations. Furthermore, in order to be remained in Olympic programs, rules and regulations of fencing should be changed and modified even faster. Studies which have done by FIE and overseas researchers report that the importance of simple attack skills is increasing while the importance of Parry & ripost, one of the most important defense skills, is decreasing in sabre. Concerning efforts of cutting down the competing time of foil and saber, they report that it is affirmative in rising understandings about fencing and reducing subjective judgements of referees. For this study, forms of tactics of internal fencers in domestic major competitions and forms of tactics of internationally high-ranked fencers are compared and the results are shown below. A. Simple attacks are given a great deal of weight. Due to shortened competing time, excessive arm movements are limited while the importance of simple attacks by initial actions of legs and final actions of arm. Then relatively, the usefulness of complex attacks has reduced. B. In defense, the importance of progressive counter attacks using competing time is raised than importance of defense using Parry & ripost. Increase of simple attacks and counter attacks cause increase of concentration and tension in matches while giving full attention for not making a little mistake in initial and final actions. C. Fast movement of legs is still used. Fleche has been forbidden and replaced by saut volant. By saut volant has been trained to make almost same speed as fleche, the proceeding time of saber shows not much difference. Rather, speed and rhythm of leg movements such as advance and retreat became more important, the importance of legs is highly increased than before. With results of mentioned above, addition of one-minute break rule and continuous cut down of competing time, which has been discussing in international fencing world, are expected to affect highly to fencing tactics. Compulsory use of transparent masks and introduction of wireless electronic scoring equipment also ask modification in operational ways of matches of fencers in saber.

靑少年을 爲한 生活體育 活性化 方案

신준호 청주대학교 교육문제연구소 1997 교육과학연구 Vol.11 No.1

人間化를 위한 生活體育

신준호 청주대학교 교육문제연구소 2000 교육과학연구 Vol.14 No.-

오늘날 현대사회는 빠른 속도로 변화하고 있다. 컴퓨터가 등장하여 청소년들의 놀이문화와 가치관 등의 변화를 가져왔고, 우리가 살고 있는 지구환경도 과학의 발전속에서 파괴되어 우리인간이 살 수 없는 곳이 생겨나고 있다. 인간의 도덕성이 상실되어 가는 현대 사회속에서 육체적, 정신적으로 건강하면서 인간이 생활하는 사회도 건강하기 위해서는 스스로의 생활속에서 이루어지는 생활체육의 필요성이 대두된다고 보며, 보다 인간다운 삶을 위해서는 삶의 질 향상도 중요하지만 도덕과 질서가 살아있는 밝은 인간사회를 추구하는데 생활체육의 필요성을 미흡 하지만 본 논문에서 살펴 보았다.

고출력 레이저에 의한 이종금속 용접특성

신호준,유영태,임기건,안동규 한국공작기계학회 2004 한국공작기계학회 추계학술대회논문집 Vol.2004 No.-

For many years and primarily for economical reasons, Dissimilar Metal Welds have been used as transition joints in a variety of equipment and applications. But Dissimilar Metal Welds have several fabrication and metallurgical drawbacks that can often lead to in-service failures. In this paper, the laser weldability of STS304 stainless steel and SM45C at dissimilar metal welds using a continuous wave Nd:YAG laser are experimentally investigated. An experimental study was conducted to determine effects of welding parameters, on eliminating or reducing the extent welding zone formation at dissimilar metal welds and to optimize those parameters that have the most influence parameters such as focus length, power, beam speed, shielding gas, and wave length of laser were tested.

體育 및 스포오츠 團體의 組織과 行政比較에 관한 硏究

申俊浩 淸州大學校 1984 論文集 Vol.17 No.1

This thesis its purpose on analysing the circnmatances and the structual aspects of the administration of physical education, studying its better development and the progressive meanings. This thesis consists of three parts: 1. It argues the development of national physical education, and suggests its theoretical values. 2. The educational conditions of our country are compared with those of the advanced countries by comparative analysis. 3. In this thesis, I deal with the important direction of the administration of physical education of our country, and Iinsist on extending the educational facilities and advancing teacher's qualities.

21세기의 생활체육 방향

신준호 청주대학교 교육문제연구소 1999 교육과학연구 Vol.13 No.-

주석도금막을 이용한 마이크로 열원에 의한 이종전자재료의 접합성에 관한 연구

신영의,윤준호 중앙대학교 기술과학연구소 1994 기술과학연구소 논문집 Vol.24 No.-

This paper has been researched bondability of electronics devices, such as lead frame and the thick film of Ag/Pd on an alumina substrate by different heat sources. To obtain the bonds with high quality, it is very important to control both the thermal distribution of the bonds and its stability, because electronics components are composed of different materials. Therefore, this paper clarifies not only heat mechanism of micro parallel gap resistance bonding method and pulse heat tip bonding method but also investigates selection of heat sources with micro-electronic materials for bonding. Finally, this paper shows fluxless bonding process with filler metal such as plating layers.

現代社會와 레크리에이션의 課題

申俊浩 淸州大學校 1985 論文集 Vol.18 No.1

This is a preliminary study on the problems and taks, social roles and strategic directions of leisure activitie incontemporary society, which is passing through rodical changes. The imporrtant tasks conlemporary recreation gace are to clarify the conceptual ambiquity of and scientify, sysmtematize acel humanize of recreation. The major roles of recreatcon in changing society is to improve the harmonizel health of Youth and People, provide sound teisure Cactivities, develop Community-orientod way of thinking and Contribute to the buil up social good health. The strategie directions of contemporary recreation lie in establishiny appropriate value system and training desirable recreation leaders.

現代社會와 社會體育에 關한 硏究

申俊浩 청주대학교 교육문제연구소 1992 교육과학연구 Vol.6 No.1