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Jo, Ji Hye,Jeon, Che Ok,Lee, Dae Sung,Park, Jong Moon Elsevier 2007 Journal of biotechnology Vol.131 No.3
<P><B>Abstract</B></P><P>Hydrogen production by the dark fermentation of food wastes is an economic and environmentally friendly technology to produce the clean energy source as well as to treat the problematic wastes. However, the long-term operations of the continuous anaerobic reactor for fermentative hydrogen production were frequently unstable. In this study, the structure of microbial community within the anaerobic reactor during unstable hydrogen production was examined by denaturing gradient gel electrophoresis (DGGE) and terminal restriction fragment length polymorphism (T-RFLP) techniques. The changes in microbial community from H<SUB>2</SUB>-producing <I>Clostridium</I> spp. to lactic acid-producing <I>Lactobacillus</I> spp. were well coincident with the unexpected process failures and the changes of metabolites concentrations in the effluent of the anaerobic reactor. As the rate of hydrogen production decreased, effluent lactic acid concentration increased. Low rate of hydrogen production and changes in microbial community were related to the ‘kimchi’ content and storage temperature of food waste feed solution. After low temperature control of the storage tank of the feed solution, any significant change in microbial community within the anaerobic reactor did not occur and the hydrogen production was very stably maintained for a long time.</P>
Moon, Phil-Dong,Han, Na-Ra,Ko, Seong-Gum,Jeong, Hyun-Ja,Kim, Su-Jin,Lee, Bo-Ra,Kim, Na-Hyung,Choi, In-Young,An, Hyo-Jin,Myung, Noh-Yil,Lee, Hyejung,Kim, Myong-Jo,Kim, Ju-Sung,Hong, Seung-Heon,Kim, Hyu Butterworths [etc.] 2010 Neurological research Vol.32 No.suppl1
<P>OBJECTIVES: Dokhwaljihwang-tang, one of the prescriptions in Four Constitution medicine, has been used to treat neurological disorders. This work was aimed to examine the effect of Dokhwaljihwang-tang on lipopolysaccharide-induced inflammatory cytokine production in peripheral blood mononuclear cells from the lesser yang subjects. METHODS: The inflammatory cytokines, interleukin 1 beta, interleukin 4 and tumor necrosis factor were measured using the ELISA. The interleukin 1 beta mRNA expression was evaluated with reverse transcriptase-polymerase chain reaction. The expression level of nuclear factor kappa B was examined by western blotting. RESULTS: Dokhwaljihwang-tang significantly inhibited interleukin 1 beta and interleukin 4 production (p<0.05). When Dokhwaljihwang-tang was pre-treated at the dose of 1 mg/ml, it not only decreased the interleukin 1 beta mRNA expression, but also inhibited the activation of nuclear factor kappa B. DISCUSSION: These results suggest the potential of Dokhwaljihwang-tang as a source of pharmaceutical acupuncture for neuronal inflammatory diseases.</P>
Ground Receiving System for KOMPSAT-2
Moon Gyu Kim,Tae Jung Kim,Hae Jin Choi,Sung Og Park,Dong Han Lee,Yong Jo Im,Ji Hyun Shin,Myung Jin Choi,Seung Ran Park,Jong Ju Lee 大韓遠隔探査學會 2003 大韓遠隔探査學會誌 Vol.19 No.3
Remote sensing division of satellite technology research center (SaTReC), Korea advanced institute of science and technology (KAIST) has developed a ground receiving and processing system for high resolution satellite images. The developed system will be adapted and operated to receive, process and distributes images acquired from of the second Korean Multi-purpose Satellite (KOMPSAT-2), which will be launched in 2004. This project had initiated to develop and Koreanize the state-of-the-art technologies for the ground receiving system for high resolution remote sensing images, which range from direct ingestion of image data to the distribution of products through precise image correction. During four years development from Dec. 1998 until Aug. 2002, the system had been verified in various ways including real operation of custom-made systems such as a prototype system for SPOT and a commercialized system for KOMPSAT-1. Currently the system is under customization for installation at KOMPSAT-2 ground station. In this paper, we present accomplished work and future work.
Fabrication and Characterization of Finite-Size DNA 2D Ring and 3D Buckyball Structures
Jo, Soojin,Kim, Seungjae,Lee, Byung Ho,Tandon, Anshula,Kim, Byunghoon,Park, Sung Ha,Kim, Moon Ki MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.7
<P>In order to incorporate functionalization into synthesized DNA nanostructures, enhance their production yield, and utilize them in various applications, it is necessary to study their physical stabilities and dynamic characteristics. Although simulation-based analysis used for DNA nanostructures provides important clues to explain their self-assembly mechanism, structural function, and intrinsic dynamic characteristics, few studies have focused on the simulation of DNA supramolecular structures due to the structural complexity and high computational cost. Here, we demonstrated the feasibility of using normal mode analysis for relatively complex DNA structures with larger molecular weights, i.e., finite-size DNA 2D rings and 3D buckyball structures. The normal mode analysis was carried out using the mass-weighted chemical elastic network model (MWCENM) and the symmetry-constrained elastic network model (SCENM), both of which are precise and efficient modeling methodologies. MWCENM considers both the weight of the nucleotides and the chemical bonds between atoms, and SCENM can obtain mode shapes of a whole structure by using only a repeated unit and its connectivity with neighboring units. Our results show the intrinsic vibrational features of DNA ring structures, which experience inner/outer circle and bridge motions, as well as DNA buckyball structures having overall breathing and local breathing motions. These could be used as the fundamental basis for designing and constructing more complicated DNA nanostructures.</P>