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RISS 인기검색어
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- 저자 : Jianping Xiang (검색결과 5 건)
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Silencing of Long Non-Coding RNA MALAT1 Promotes Apoptosis of Glioma Cells
Jianping Xiang,Shifeng Guo,Shuling Jiang,Yuelong Xu,Jiwei Li,Li Li,Jinyu Xiang 대한의학회 2016 Journal of Korean medical science Vol.31 No.5
The metastasis-associated lung adenocarcinoma transcription 1 (MALAT1) is a highly conserved long non-coding RNA (lncRNA) gene. However, little is known about the pathological role of lncRNA MALAT1 in glioma. In the present study, we explored the expression level of lncRNA MALAT1 in primary glioma tissues as well as in U87 and U251 glioma cell lines. Using qRT-PCR, we found that the expression of lncRNA MALAT1 was significantly increased in glioma tissues compared with that of paracancerous tissues. Meanwhile, the expression of MALAT1 was highly expressed in U98 and U251 cells. In order to explore the function of MALAT1, the expression of MALAT1 was greatly reduced in U87 and U251 cells transfected with siRNA specifically targeting MALAT1. Consequently, cell viability of U87 and U251 cells were drastically decreased after the knockdown of MALAT1. Concomitantly, the apoptosis rate of the two cell lines was dramatically increased. Furthermore, the expression levels of some tumor markers were reduced after the knockdown of MALAT1, such as CCND1 and MYC. In summary, the current study indicated a promoting role of MALAT1 in the development of glioma cell.
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Asymmetrical Pulse-Width-Modulated Full-Bridge Secondary Dual Resonance DC–DC Converter
Zhangyong Chen,Qun Zhou,Jianping Xu,Xiang Zhou 전력전자학회 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6
A full-bridge secondary dual-resonant DC?DC converter using the asymmetrical pulse-width modulated (APWM) strategy is proposed in this paper. The proposed converter achieves zero-voltage switching for the power switches and zero-current switching for the rectifier diodes in the whole load range without the help of any auxiliary circuit. Given the use of the APWM strategy, a circulating current that exists in a traditional phase-shift full-bridge converter is eliminated. The voltage stress of secondary rectifier diodes in the proposed converter is also clamped to the output voltage. Thus, the existing voltage oscillation of diodes in traditional PSFB converters is eliminated. This paper presents the circuit configuration of the proposed converter and analyzes its operating principle. Experimental results of a 1 kW 385 V/48 V prototype are presented to verify the analysis results of the proposed converter.
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Liang Ma,Guolin Xiang,Yuan Huang,Meng-Ya He,Jianping Li,Pengbo Fu 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.85 No.-
Afluidized bed has the advantages of treating largeflows, intensifying mass and heat transfer, andlowering costs. This study proposed a cyclonicfluidized bed packed with spherical activated carbonadsorbents for volatile organic compounds adsorption. Thefluidization and self-rotation of the ACparticles in a 25 mm cyclonicfluidized bed were studied with high-speed camera testing technology. Theeffects of the particle movement on the adsorption efficiency of toluene were also tested. The resultsshow that most of the particles at the inlet side of the cyclonicfluidized bed were moving up when theinlet airflow rate was greater than 2.0 m3/h. The particles began to move in clusters when the relativepacking height increased to a critical value of 0.57. Increasing the gasflow rate and the diameter andheight of the core column will increase the self-rotation speed of the total particles. The maximum selfrotationspeed of spherical adsorbents reached 1700 rad/s at the inletflow rate of 2.5 m3/h. In the case ofthe same axial velocity of the gas phase in the upper space of the core column, increasing the particle selfrotationspeed can slightly improve the adsorption efficiency. The maximum adsorption efficiencyreached 99% when the inletflow rate is 1.0 m3/h with relative packing height 0.65.
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Xinzhong Deng,Yao-wu Wang,Jianping Peng,Kejia Liu,Nai-xiang Feng,Yuezhong Di 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2017 NANO Vol.12 No.2
A facile cathodic electrodeposition process was developed to prepare Mg(OH)2/Graphene nanocomposites (MGN), which was used to remove Congo Red (CR), an anionic dye from aqueous solution. The morphology and phase structure were analyzed by transmission electron microscopy (TEM), X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET), Raman and X-ray photoelectron spectroscopy (XPS). The effects of experimental parameters, such as graphene content, adsorption time, initial concentrations of CR and pH values, on the adsorption capacity of CR were studied. The obtained MGN shows the good performance in CR, with an adsorption capacity of 1986.43 mg g-1. The equilibrium adsorption and kinetics data fit with Langmuir isotherm and the pseudo-second-order model, respectively. Thermodynamic data suggest that CR adsorption onto MGN is spontaneous (ΔG0 : –9.62 kJ mol-1 at 313 K, endothermic (ΔH0 : 36.261 kJ mol-1) and the degree of disorder increased (ΔS0 : 146.848 J moL-1 K-1) at the solidsolution interface. Moreover, the adsorption activation energy (Ea: 38.929 kJ mol-1) of CR evaluated from the Arrhenius equation illustrates that it is a physical process. This adsorbent exhibits efficient adsorption properties and high recycling efficiency, making it a promising adsorbent for removing anionic dyes.
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Asymmetrical Pulse-Width-Modulated Full-Bridge Secondary Dual Resonance DC-DC Converter
Chen, Zhangyong,Zhou, Qun,Xu, Jianping,Zhou, Xiang The Korean Institute of Power Electronics 2014 JOURNAL OF POWER ELECTRONICS Vol.14 No.6
A full-bridge secondary dual-resonant DC-DC converter using the asymmetrical pulse-width modulated (APWM) strategy is proposed in this paper. The proposed converter achieves zero-voltage switching for the power switches and zero-current switching for the rectifier diodes in the whole load range without the help of any auxiliary circuit. Given the use of the APWM strategy, a circulating current that exists in a traditional phase-shift full-bridge converter is eliminated. The voltage stress of secondary rectifier diodes in the proposed converter is also clamped to the output voltage. Thus, the existing voltage oscillation of diodes in traditional PSFB converters is eliminated. This paper presents the circuit configuration of the proposed converter and analyzes its operating principle. Experimental results of a 1 kW 385 V/48 V prototype are presented to verify the analysis results of the proposed converter.
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