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Role of Endoscopy in the Management of Boerhaave Syndrome
Juan Ignacio Tellechea,Jean-Michel Gonzalez,Pablo Miranda-García,Adrian Culetto,Xavier Benoit D’Journo,Pascal Alexandre Thomas,Marc Barthet 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.2
Boerhaave syndrome (BS) is a spontaneous esophageal perforation which carries high mortality. Surgical treatment is well established,but the development of interventional endoscopy has proposed new therapies. We expose our experience in a Gastrointestinal andEndoscopy Unit. With a retrospective, observational, open-label, single center, consecutive case series. All patients diagnosed withBS who were managed in our center were included. Treated conservatively, endoscopically or surgically, according to their clinicalcondition and lesion presentation. Fourteen patients were included. Ten were treated with primary surgery. One conservatively. In total,7/14 patients required an endoscopic treatment. All required metallic stents deployment, 3 cases over-the-scope-clips concomitantlyand one case a novel technique an internal drain. 6/7 cases endoscopically treated achieved complete esophageal healing. In conclusion,endoscopy is an useful tool at all stages BS management: difficult diagnosis, primary treatment in selected patients and as salvage whensurgery fails. With mortality rates and outcomes comparables to surgery.
Chemical functionalization of single walled carbon nanotubes
Urszula Dettlaff-Weglikowska,Jean-Michel Benoit,Po-Wen Chiu,Ralf Graupner,Sergey Lebedkin,Siegmar Roth 한국물리학회 2002 Current Applied Physics Vol.2 No.6
Chemical modication has been performed on puried single walled carbon nanotubes. XPS spectrum shows that the peaksequent coupling reactions were carried out with diamine molecules to form intertube connections. Tripropylentetramine andphenylendiamine have been chosen as a molecular linker. End-to-side and end-to-end nanotube interconnections are formed andthen observed by atomic force microscopy (AFM). Statistical analysis made from AFM images shows around 30% junctions infunctionalized and less than 2% in pristine material. Remarkable features can be observed in the Raman spectra at dierentfunctionalization steps. Simple conductance measurements on bucky papers prepared from prestine nanotubes and from nanotubes. 2002 Elsevier Science B.V. All rights reserved.