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- 저자 : Jae Mok Soh (검색결과 4 건)
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Parameter Study of Boiling Model for CFD Simulation of Multiphase-Thermal Flow in a Pipe
Soh-Myung Chung,Yong-Seok Seo,Gyu-Mok Jeon,Jae-Won Kim,Jong-Chun Park 한국해양공학회 2021 韓國海洋工學會誌 Vol.35 No.1
The demand for eco-friendly energy is expected to increase due to the recently strengthened environmental regulations. In particular, the flow inside the pipe used in a cargo handling system (CHS) or fuel gas supply system (FGSS) of hydrogen transport ships and hydrogen-powered ships exhibits a very complex pattern of multiphase-thermal flow, including the boiling phenomenon and high accuracy analysis is required concerning safety. In this study, a feasibility study applying the boiling model was conducted to analyze the multiphase-thermal flow in the pipe considering the phase change. Two types of boiling models were employed and compared to implement the subcooled boiling phenomenon in nucleate boiling numerically. One was the "Rohsenow boiling model", which is the most commonly used one among the VOF (Volume-of-Fluid) boiling models under the Eulerian-Eulerian framework. The other was the "wall boiling model", which is suitable for nucleate boiling among the Eulerian multiphase models. Moreover, a comparative study was conducted by combining the nucleate site density and bubble departure diameter model that could influence the accuracy of the wall boiling model. A comparison of the Rohsenow boiling and the wall boiling models showed that the wall boiling model relatively well represented the process of bubble formation and development, even though more computation time was consumed. Among the combination of models used in the wall boiling model, the simulation results were affected significantly by the bubble departure diameter model, which had a very close relationship with the grid size. The present results are expected to provide useful information for identifying the characteristics of various parameters of the boiling model used in CFD simulations of multiphase-thermalflow, including phase change and selecting the appropriate parameters.
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Chemotherapeutic Evaluation of Tiberal(Ro7-0207) in Entamoeba histolytica, Giardia lamblia, and
Chang, Jae-Kyung,Cho, Kee-Mok,Lee, Kun-Soo,Soh, Chin-Thack INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1976 YONSEI REPORTS ON TROPICAL MEDICINE Vol.7 No.1
對象者로서 無症勢痢疾아메바保囊者 60名, 輕症勢痢疾아메바保囊者 40名, 肝아메바症患者 20名, 람불鞭毛蟲感染者 30名 및 膣트리코모나스症患者 20名을 選定하고 二重盲檢試驗法(Tiberal : Metronidazole, 또는 Tiberal : Metronidazole : Placebo)에 依하여 各各 投藥한 後 其 治療效果 및 耐性 等을 比較評價하였다. 各 藥劑의 用量은 1日量을 6歲以下 250mg, 7∼12歲 500mg, 12歲以上 1.0gm로 하여 2回로 分服, 7日間 繼續 經口投與하였다. 無症勢痢疾아메바保囊者에 있어서는 完全驅蟲된 者가 Tiberal 投與群에서 20名中 18名, Metronidazole投與群 20名中 14名이었으며 投藥完了後 再發된 者는 Tiberal投與群에서 2名, Metronidazole投與群에서 3名이 되었고 無效果者는 Metronidazole投與群에서 1名이 있었다. 輕症勢痢疾아메바保囊者에 있어서는 Tiberal과 Metronidazole 兩藥劑 投與群에 있어서 投藥開始 5日 後부터 本蟲囊子의 推出이 陰轉되었으나 投與完了後 1∼2週에 再發된 者가 Tiberal 投與群에서 20名中 2名, Metronidazole投與群 20名中 3名이 있었다. 肝아메바症患者에 있어서는 兩藥劑가 共히 臨床的 및 寄生蟲學的 諸檢査에 있어서 滿足할만한 效果를 보였다. 또한 治療後 6個月間의 追後觀察結果에 있어서도 再發된 者가 全然 없었다. 람불鞭毛蟲感染者에 있어서는 投藥直後 糞便中의 本蟲蟲囊推出이 兩投藥群에 있어서 모두 陰轉되었으나 追後檢査에 있어서 Metronidazole投與群 10名中 1名이 再發되었다. 트리코모나스性膣炎患者에 있어서는 兩藥劑 投與群이 投藥開始後 모두 臨床的 諸症勢의 好轉 및 本蟲의 陰轉等 著效를 보였으나 追後檢査에 있어서 再發된 者가 Tiberal投與群 10名 中 投藥終了 2個月後에, Metronidazole投與群 10名中 投藥終了 2週 後에 各各 1名式 있었다. 各 藥劑의 腸內 ?蟲類에 對한 驅蟲效果는 全然 期待될 수 없었으며 Placebo投與群에 있어서도 投藥前後에 差異가 없었다. 各 藥劑의 耐性에 있어서는 Tiberal投與群은 모두 滿足할만 하였으나 Metronidazole投與群에 있어서 70名中 4名에서 眩量, 嘔逆, 上腹通, 皮膚發疹 等의 副作用이 觀察되었다. 各症勢는 모두 輕하였고 一時的이었으나 皮膚發疹만은 急速히 進展되었으며 投藥中止後에야 徐徐히 消失되었다.
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Prevalence of Intestinal Parasites in Sochong-Do Island
Cho, Kee-Mok,Soh, Chin-Thack,Lee, Kun-Soo,Chang, Jae-Hoon INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1976 YONSEI REPORTS ON TROPICAL MEDICINE Vol.7 No.1
1976年 2月∼5月間에 小靑島住民 總 575名中 367名(63.8%) 및 對照群 84名을 對象으로 Modified MIFC法 (Cho et al., 1972)으로서 腸內寄生蟲 感染實態를 調査하였다. 島民 367名中男子 154名, 女子 213名이었다. 其中 腸內연蟲類感染者는 322名(87.7%)이었으며 種別感染率은 蛔蟲 79.6%, 鞭蟲 45.2%, 鉤蟲 0.3%, 寸蟲 0.3%였다. 對照群의 腸內연蟲類感染者는 36名(42.7%) 이었으며, 蛔蟲 36.9%, 鞭蟲 15.5%였다. 島民中 腸內原蟲類感染者는 44名(12.0%)이었으며 痢疾아메바 1.4%, 大腸아메바 10.4%, 矮小아메바 1.6%, 람불鞭毛蟲 0.8%였다. 對照群의 腸內原蟲類感染者는 4名(4.8%)이었으며 大腸아메바 1.2%, 람불鞭毛蟲 3.6%였다. 性別感染率은 ?蟲類나 原蟲類에 있어서 모두 女子가 높았다. 年齡別 感染率은 ?蟲類感染者에 있어서 10∼19歲群이 가장 높았으며(95.5%), 其他 年齡群에 있어서는 80.3% 乃至 91.4%였다. 한편 原蟲類 感染者에 있어서는 40∼49歲群이 가장 높았고(21.7%), 10歲以下群이 가장 낮았다. 年齡群 順位別로 調査한 ?蟲類重複感染率은 二頂曲線에 近似한 分布를 나타냈다. 總體的으로 本島民의 腸內寄生蟲 感染率은 國內他地方 및 島嶼에 比하여 ?蟲類(特히 蛔蟲)에 있어서는 가장 높았으며 原蟲類에 있어서는 낮았다.
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Sujata Acharjee,Kaushik Maiti,Jae Mok Soh,Wook-Bin Im,Jae Young Seong,Hyuk Bang Kwon 한국분자세포생물학회 2002 Molecules and cells Vol.14 No.1
We previously demonstrated the presence of three dis-tinct types of the gonadotropin-releasing hormone re-ceptor (GnRHR) in a bullfrog (denoted bfGnRHR-1, bfGnRHR-2, and bfGnRHR-3). The bfGnRHRs exhib-ited differential tissue distribution and ligand selectiv-ity. In the present study, we demonstrated the desensi-tization and internalization kinetics of these receptors in both transiently-transfected HEK293 cells and ret-rovirus-mediated stable cells. The time-course accu-mulation of the inositol phosphate in response to GnRH revealed that bfGnRHR-1 and -2 were rapidly desensitized, whereas bfGnRHR-3 was slowly desensi-tized. A comparison of the internalization kinetics re-vealed the most rapid rate and highest extent of inter-nalization of bfGnRHR-2 among the three receptors. Interestingly, the mechanisms that underlie the recep-tor internalization appear to differ from each other. Internalization of bfGnRHR-1 was dependent on both dynamin and b-arrestin, whereas those of bfGnRHR-2 and -3 were dependent on dynamin, but not on b-arrestin. These results, therefore, suggest that differen-tial regulatory mechanisms for desensitization and internalization of the GnRHR are involved in diverse cellular and physiological responses to GnRH stimula-tion.
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