http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Jang, Woongsik,Cheon, Hyungin,Park, Soyun,Cho, Jae Sang,Yi, Minji,Kwon, Soon-Ki,Kim, Yun-Hi,Wang, Dong Hwan Applied Science Publishers 2017 Dyes and pigments Vol.145 No.-
<P><B>Abstract</B></P> <P>We synthesized PP-TPD, based on a phenanthro[1,10,9,8-cdefg]carbazole unit as a donor and a thieno [3,4-c]pyrrole-4,6-dione (TPD) unit as an acceptor for efficient bulk heterojunction photovoltaic cells. The copolymer achieves a relatively low bandgap (1.6 eV) by its internal charge-transfer, which concurs with the results of density functional theory (DFT) calculation for the distribution of HOMO and LUMO levels. In addition, we fabricated the bulk-heterojunction (BHJ) photovoltaic cells as a function of the blend ratio of the donor (PP-TPD) and acceptor (PC<SUB>70</SUB>BM), and applied a solvent additive and an interlayer to the device, with the optimized ratio used in this study. To comprehend the relationships between the device performance and the synergetic effects of 1,8-diiodooctane (DIO) and titanium oxide (TiO<SUB>x</SUB>) within the PP-TPD: PC<SUB>70</SUB>BM blends, we investigated the hole mobility related to the charge carrier transport, the charge generation, and the charge transport resistance using space-charge limited current (SCLC) measurement, photocurrent analysis, and impedance spectroscopy, respectively. Especially, we implemented fluorescence imaging by Raman spectroscopy, which related to the charge generation and recombination dynamics within the surface of photoactive areas.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PP-TPD copolymer revealed well-distribution of HOMO/LUMO and band-gap of 1.6 eV. </LI> <LI> PP-TPD copolymer was designed to improve intermolecular interaction and carrier mobility. </LI> <LI> Interface engineering via additive and interlayer affects homogeneous thin film morphology. </LI> <LI> Enhanced electrical parameters of Voc, Jsc, and FF are analyzed by charge carrier dynamics. </LI> <LI> Fluorescence imaging was conducted for the study of charge generation and recombination. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
A novel adipokine CTRP1 stimulates aldosterone production
Jeon, Jun Ho,Kim, Kun‐,yong,Kim, Jae Hyeong,Baek, Ahmi,Cho, Hyungin,Lee, Young Ho,Kim, Jong Wan,Kim, Dohee,Han, Seung Hyun,Lim, Jong‐,Seok,Kim, Keun Il,Yoon, Do Young,Kim, Soo‐,Hyun Federation of American Society for Experimental Bi 2008 The FASEB Journal Vol.22 No.5
<P>Complement-C1q TNF-related protein 1 (CTRP1), a member of the CTRP superfamily, is expressed at high levels in adipose tissues of obese Zucker diabetic fatty (fa/fa) rats, and CTRP1 expression is induced by proinflammatory cytokines, including TNF-alpha and IL-1beta. In the present study, we investigated stimulation of aldosterone production by CTRP1, since it was observed that CTRP1 was specifically expressed in the zona glomerulosa of the adrenal cortex, where aldosterone is produced. Increased aldosterone production by CTRP1 in cells of the human adrenal cortical cell line H295R was dose-dependent. Expression levels of aldosterone synthase CYP11B2 were examined to investigate the molecular mechanisms by which CTRP1 enhances the production of aldosterone. The expression of CYP11B2 was greatly increased by treatment with CTRP1, as was the expression of the transcription factors NGFIB and NURR1, which play critical roles in stimulation of CYP11B2 gene expression. It was also revealed that angiotensin II-induced aldosterone production is, at least in part, mediated by the stimulation of CTRP1 secretion, not by the increase of CTRP1 mRNA transcription. In addition, the levels of CTRP1 were significantly up-regulated in hypertensive patients' serum. As CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension.</P>