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Occupational Health Policies on Risk Assessment in Japan
Horie, Seichi Occupational Safety and Health Research Institute 2010 Safety and health at work Vol.1 No.1
Industrial Safety and Health Law (ISH Law) of Japan requires abnormalities identified in evaluations of worker health and working environments are reported to occupational physicians, and employers are advised of measures to ensure appropriate accommodations in working environments and work procedures. Since the 1980s, notions of a risk assessment and occupational safety and health management system were expected to further prevent industrial accidents. In 2005, ISH Law stipulated workplace risk assessment using the wording "employers shall endeavor." Following the amendment, multiple documents and guidelines for risk assessment for different work procedures were developed. They require ISH Laws to be implemented fully and workplaces to plan and execute measures to reduce risks, ranking them from those addressing potential hazards to those requiring workers to wear protective articles. A governmental survey in 2005 found the performance of risk assessment was 20.4% and common reasons for not implementing risk assessments were lack of adequate personnel or knowledge. ISH Law specifies criminal penalties for both individuals and organizations. Moreover, under the Labor Contract Law promulgated in 2007, employers are obliged to make reasonable efforts to ensure employee health for foreseeable and avoidable risks. Therefore, enterprises neglecting even the non-binding provisions of guidelines are likely to suffer significant business impact if judged to be responsible for industrial accidents or occupational disease. To promote risk assessment, we must strengthen technical, financial, and physical support from public-service organizations, encourage the dissemination of good practices to reduce risks, and consider additional employer incentives, including relaxed mandatory regulations.
Hori, Takeshi,Kondo, Takashi,Lee, Hyemi,Song, Chang W.,Park, Heon Joo Informa UK, Ltd. 2011 International journal of hyperthermia Vol.27 No.1
<P><I>Purpose:</I> The anti-cancer effect of &bgr;棺-lapachone (&bgr;棺-lap) is positively related to the cellular activity of NAD(P)H:quinone oxidoreductase (NQO1). Heat shock has been reported to elevate cellular NQO1. The effect of heating on the NQO1 expression in human osteosarcoma cells (HOS) and the response of the cells to the combined treatment with &bgr;棺-lap and hyperthermia was investigated.</P><P><I>Materials and methods:</I> The effects of &bgr;棺-lap alone, hyperthermia alone and in combination to cause clonogenic death and apoptosis in HOS cells were elucidated. The effect of heating on the NQO1expression was evaluated with western blot analysis. The effect of &bgr;棺-lap on the cell cycle distribution was elucidated with flow cytometry and to cause DNA damage was determined by assessing the <I>&ggr;款</I>H2AX foci formation.</P><P><I>Results:</I> Treatment of HOS cells with &bgr;棺-lap at 42°째C was markedly more effective than that at 37°째C in causing clonogenic cell death. Heating caused a long-lasting up-regulation of NQO1 in the cells, and sensitised the cells to &bgr;棺-lap. The <I>&ggr;款</I>H2AX foci formation was increased immediately after &bgr;棺-lap treatment and preheating increased the &bgr;棺-lap-induced <I>&ggr;款</I>H2AX foci formation.</P><P><I>Conclusions:</I> The sensitivity of HOS cells to &bgr;棺-lap was increased not only during heating but also after heating as demonstrated by the increase in the clonogenic cell death and <I>&ggr;款</I>H2AX foci formation. The increase in &bgr;棺-lap sensitivity after heating appeared to be due to the heat-induced elevation of NQO1 activity.</P>
Horie, Yukihiro,Meguro, Akira,Kitaichi, Nobuyoshi,Lee, Eun Bong,Kanda, Atsuhiro,Noda, Kousuke,Song, Yeong Wook,Park, Kyung Sook,Namba, Kenichi,Ota, Masao,Inoko, Hidetoshi,Mizuki, Nobuhisa,Ishida, Susu Oxford University Press ; Distributed by Mercury I 2012 Rheumatology Vol.51 No.6
<P>Beh?et's disease is one of the major aetiologies of uveitis causing blindness in Asian countries. A genome-wide association study identified six microsatellite markers as disease susceptibility loci for Japanese patients with Beh?et's disease. To confirm our recent results, these microsatellite markers were examined in a Korean population as a replication study.</P>
Estimation Method of the Positions of Reinforcing Steel Bars by using Pulsed-Magnetization
Hori, Michitaka,Sana, Ryousuke,Komori, Mochimitsu 대한전기학회 2014 The Journal of International Council on Electrical Vol.4 No.4
Recently, the inspection of positions and depths of reinforcing steel bars in reinforced concrete structures is important. An electromagnetic induction method and an electromagnetic radiation radar method are used for inspection techniques of nondestructive. But, a general inspection technique also has the problem. Other techniques are actively researched now. Authors previously proposed a method of estimating position, depth and diameter of a single reinforcing steel bar by using the pulse-magnetization. In most cases reinforcing steel bars are usually found in more than one the reinforcing steel bars. Authors examined the method estimating the positions of reinforcing steel bars in more than one the reinforcing steel bars. The magnetization characteristic of the reinforcing steel bar was examined, Authors confirmed about the technique for estimating of the position of the reinforcing steel bar through the basic experiments and simulations, and report.
A human cDNA sequence homologue of bovine phosphatidylethanolamine-binding protein
Hori, Naohiro,Chae, Keon-sang,Murakawa, Katsuji,Matoba, Ryo,Fukushima, Atsusi,Okubo, Kousaku,Matsubara, Kenichi 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.17 No.-
Sequencing of about 1000 3'-directed cDNA clones from the human HepG2 cell line revealed that about half of them represent transcripts of abundantly or moderately expressed genes, about 70% of which are novel We identified one of these clones as encoding the human homologue of bovine phosphatidylethanolamine-binding protein.
Recent Advances of Nutritional Physiology and Artificial Diet of the silkworm, Bombyx mori, in Japan
Horie, Yasuhiro 한국잠사학회 1995 한국잠사곤충학회지 Vol.37 No.2
Recently, the cocoon production is reducing very steeply in Japan. The main reason for this cocoon reduction is due to high labor cost and the production expense is apt to rise year by year. Accordingly, the improvement of cocoon productivity by retrenchment of the production expense is intensively required in my country. Therefore, the silkworm rearing on the artificial diet is largely expected as the innovation techniques of sericulture. Since rearing of the silkworm on artificial diets has first been achieved in 1960, and the silkworm larvae were reared throughout all the instars on artificial diets(Fukuda et al., 1960, Ito &Tanaka, 1960). The artificial diets used at this time contained 50% or more of dried, pulverized mulberry leaves as one of the main ingredients, and the composition was rather simple. When reared on these diets, larval growth and development were retarded, small cocoons appeared, and the adults laid only a small number of eggs. At first, we would like to study about nutritional requirement of the silkworm, using the chemically defined diet which prepared artificially. Subsequently, attempts were made to improve the diets by replacement of crude ingredients with possibly purer compounds, as mentioned later. Before giving the details on individual nutrient, I would like to summarize about the outline of utilization flow of various nutrients through the larval-pupal development and these daily quantitative requirements per body weight in the silkworm when they were reared on mulberry leaves.
Hori, Yusuke,Kurino, Haruhiko,Kurokawa, Yasushi Council on Tall Building and Urban Habitat Korea 2016 International journal of high-rise buildings Vol.5 No.3
This paper describes a large tuned mass damper (TMD) developed as an effective seismic control device for an existing highrise building. To realize this system, two challenges needed to be overcome. One was how to support a huge mass that has to move in any direction, and the second was how to control mass displacement that reaches up to two meters. A simple pendulum mechanism with strong wires was adopted to solve the first problem. As a solution to the important latter problem, we developed a high-function oil damper with a unique hydraulic circuit. When the mass velocity reaches a certain value, which was predetermined by considering the permissible displacement, the damper automatically and drastically increases its damping coefficient and limits the mass velocity. This velocity limit function can effectively and stably control the mass displacement without any external power. This paper first examines the requirements of the TMD using a simple model and clarifies the constitution of the actual TMD system. Then the seismic upgrading project of an existing high-rise building is outlined, and the developed TMD system and the results of performance tests are described. Finally, control effects for design earthquakes are demonstrated through response analyses and construction progress is introduced.