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        Synthesis and Application of Reactive Dyes Based on Azo-Anthraquinone Skeleton to Realize Clean Printing of Cotton Fabrics

        Hongjuan Zhang,Liujun Pei,Shuaitong Liang,Qun Wang,Jingming Huang,Xiaomin Gu,Jiping Wang 한국섬유공학회 2021 Fibers and polymers Vol.22 No.5

        Traditional reactive dyes generate a large amount of colored wastewater during printing owing to low reactivity,causing severe environmental problems. In this investigation, four novel reactive dyes were synthesized via incorporating azostructure into anthraquinone chromophore. They were characterized by UV-Vis, FT-IR, and 1H-NMR spectra. Their printingproperties on cotton fabric were comprehensively studied. Attributed to multifunctional groups, the fixation of the novelreactive dyes can reach 98 % even at the dye concentration of 10 %. It increases by 30 % compared with traditionalanthraquinone dyes. Moreover, the reactive dyes containing both mono-chlortriazine and bis(sulfatoethylsufone) groups canachieve urea-free printing. This research has a potential and significant application in the cleaner production of printing forcotton fabrics.

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        Akkermansia muciniphila postbiotic administration mitigates choline-induced plasma Trimethylamine-N-Oxide production in mice

        Xu Hongjuan,Bian Xiaoyun,Wang Hongxing,Huang Lin,Chen Xiaoxi 한국응용생명화학회 2024 Applied Biological Chemistry (Appl Biol Chem) Vol.67 No.-

        Trimethylamine-N-Oxide (TMAO) is believed to be linked to increased likelihood of cardiovascular disease. While probiotics have shown limited effectiveness in reducing TMAO levels, the potential of postbiotics remains underexplored. This study aimed to evaluate the impact of Akkermansia muciniphila ( A. muciniphila ) postbiotic administration on choline-induced TMAO production in mice by modifying the gut microbiota. Female C57BL/6J mice were divided into six groups, including a control group, high-choline diet group, live A. muciniphila probiotic group, pasteurized A. muciniphila postbiotic group, sodium butyrate group, and sodium propionate group. Various measurements and analyses were conducted, including TMAO and TMA levels in serum, urine, and cecal contents, as well as the expression of FXR and FMO3 in liver tissues. Additionally, metabolic parameters, body weight, serum lipid profile, hepatic protein expression (FMO3, FXR, CutC, and CutD), and gut microbiota composition were assessed. Administration of A. muciniphila postbiotic significantly reduced choline-induced plasma TMAO levels in mice. Furthermore, improvements in serum lipid profiles and liver enzyme levels suggested potential enhancements in lipid metabolism and liver function. The study also observed modulation of specific proteins related to TMAO production and metabolism, including CutC and CutD. The findings highlight the potential of A. muciniphila postbiotics as a dietary strategy for mitigating cardiovascular disease risk by modulating the gut-TMAO axis. Postbiotics, particularly A. muciniphila , offer advantages over probiotics and warrant further investigation for their therapeutic applications in gastrointestinal and metabolic disorders. Background Trimethylamine-N-Oxide (TMAO) is believed to be linked to increased likelihood of cardiovascular disease. While probiotics have shown limited effectiveness in reducing TMAO levels, the potential of postbiotics remains underexplored. This study aimed to evaluate the impact of Akkermansia muciniphila (A. muciniphila) postbiotic administration on choline-induced TMAO production in mice by modifying the gut microbiota. Methods Female C57BL/6J mice were divided into six groups, including a control group, high-choline diet group, live A. muciniphila probiotic group, pasteurized A. muciniphila postbiotic group, sodium butyrate group, and sodium propionate group. Various measurements and analyses were conducted, including TMAO and TMA levels in serum, urine, and cecal contents, as well as the expression of FXR and FMO3 in liver tissues. Additionally, metabolic parameters, body weight, serum lipid profile, hepatic protein expression (FMO3, FXR, CutC, and CutD), and gut microbiota composition were assessed. Results Administration of A. muciniphila postbiotic significantly reduced choline-induced plasma TMAO levels in mice. Furthermore, improvements in serum lipid profiles and liver enzyme levels suggested potential enhancements in lipid metabolism and liver function. The study also observed modulation of specific proteins related to TMAO production and metabolism, including CutC and CutD. Conclusion The findings highlight the potential of A. muciniphila postbiotics as a dietary strategy for mitigating cardiovascular disease risk by modulating the gut-TMAO axis. Postbiotics, particularly A. muciniphila, offer advantages over probiotics and warrant further investigation for their therapeutic applications in gastrointestinal and metabolic disorders.

      • Compounds from the subterranean part of Johnsongrass and their allelopathic potential

        Liu, Yan,Zhang, Chaoxian,Wei, Shouhui,Cui, Hailan,Huang, Hongjuan The Korean Society of Weed Science and The Turfgra 2011 Weed Biology and Management Vol.11 No.3

        The allelopathic effects of the exotic invasive weed, Johnsongrass, on Lactuca sativa, a native plant in China, were evaluated and the phytotoxins were investigated under laboratory conditions. The crude extracts (chloroform and ethyl acetate fractions) that were obtained from the ethanol extract of the subterranean parts of Johnsongrass inhibited the germination speed and growth of the roots and shoots of the test plant. The four compounds, ethyl p-hydroxybenzoate, diosmetin, apigenin, and luteolin, were isolated from the extract of the subterranean parts of Johnsongrass first, along with three other compounds (reported previously), p-hydroxybenzaldehyde, p-hydroxybenzoic acid, and dhurrin, and they all were evaluated on L. sativa. At the concentration of <0.5 mmol $L^{-1}$, ethyl p-hydroxybenzoate, dhurrin, and the mixture of the compounds delayed the germination speed of the seeds of L. sativa at 24 h of incubation, while apigenin delayed the germination speed of the seeds of L. sativa at 72 h of incubation. Ethyl p-hydroxybenzoate demonstrated the strongest delaying effect among the phenols and a similar effect was found with apigenin among the flavonoids, wheras ethyl p-hydroxybenzoate induced a drastic inhibition of the germination at 2 mmol $L^{-1}$. In contrast, p-hydroxybenzaldehyde and luteolin had no effect on the germination at any concentration at any stage. All the substances inhibited the shoot and root growth of L. sativa at 3 mmol $L^{-1}$. Increasing the concentration increased the inhibition of the growth of L. sativa.The inhibitory activity of ethyl p-hydroxybenzoate and p-hydroxybenzaldehyde was greater than that of the other compounds. This result suggested that the isolated phytotoxins might contribute to the successful invasion by Johnsongrass.

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