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      • Damage detection of subway tunnel lining through statistical pattern recognition

        Yu, Hong,Zhu, Hong P.,Weng, Shun,Gao, Fei,Luo, Hui,Ai, De M. Techno-Press 2018 Structural monitoring and maintenance Vol.5 No.2

        Subway tunnel structure has been rapidly developed in many cities for its strong transport capacity. The model-based damage detection of subway tunnel structure is usually difficult due to the complex modeling of soil-structure interaction, the indetermination of boundary and so on. This paper proposes a new data-based method for the damage detection of subway tunnel structure. The root mean square acceleration and cross correlation function are used to derive a statistical pattern recognition algorithm for damage detection. A damage sensitive feature is proposed based on the root mean square deviations of the cross correlation functions. X-bar control charts are utilized to monitor the variation of the damage sensitive features before and after damage. The proposed algorithm is validated by the experiment of a full-scale two-rings subway tunnel lining, and damages are simulated by loosening the connection bolts of the rings. The results verify that root mean square deviation is sensitive to bolt loosening in the tunnel lining and X-bar control charts are feasible to be used in damage detection. The proposed data-based damage detection method is applicable to the online structural health monitoring system of subway tunnel lining.

      • KCI등재

        Serum Insulin-Like Growth Factor Binding Protein 7 as a Potential Biomarker in the Diagnosis and Prognosis of Esophagogastric Junction Adenocarcinoma

        Can-Tong Liu,Yi-Wei Xu,Hong Guo,Chao-Qun Hong,Xin-Yi Huang,Yu-Hao Luo,Shi-Han Yang,Ling-Yu Chu,En- Min Li,Yu-Hui Peng 거트앤리버 소화기연관학회협의회 2020 Gut and Liver Vol.14 No.6

        Background/Aims: Esophagogastric junction adenocarcinoma (EJA) is a malignant tumor associated with high morbidity and has attracted increasing attention due to a rising incidence and low survival rate. Pathological biopsy is the gold standard for diagnosis, but noninvasive and effective tests are lacking, resulting in diagnoses at advanced stages. This study explored the diagnostic value of insulin-like growth factor binding protein 7 (IGFBP7) in EJA. Methods: A total of 120 EJA patients and 88 normal controls were recruited, and their serum levels of IGFBP7 were measured by enzymelinked immunosorbent assay. Receiver operating characteristic (ROC) curve analysis was used to assess the diagnostic value, and Pearson chi-square analysis was used to evaluate the correlation between IGFBP7 and clinical parameters. Kaplan- Meier survival analysis was carried out to assess the effect of IGFBP7 on overall survival (OS). Results: The levels of IGFBP7 were higher in both early- and late-stage EJA patients than in normal controls (p<0.001). The area under the ROC curve for EJA patients was 0.794 (95% confidence interval [CI], 0.733 to 0.854), with a cutoff value of 2.716 ng/mL, a sensitivity of 63.3% (95% CI, 54.0% to 71.8%) and a specificity of 90.9% (95% CI, 82.4% to 95.7%). For the diagnosis of early-stage EJA, the same cutoff value and specificity were obtained, but the sensitivity of IGFBP7 was 54.3% (95% CI, 36.9% to 70.8%). Patients with low IGFBP7 protein expression had lower OS than those with high expression (p=0.034). The multivariate analysis showed that IGFBP7 is an independent prognostic factor for EJA (p=0.011). Conclusions: Serum IGFBP7 acts as a potential diagnostic and prognostic marker for EJA.

      • KCI등재

        Cavitation pulse extraction and centrifugal pump analysis

        Hong Li,Bo Yu,Biao Qing,Shaoran Luo 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.3

        This study extracted cavitation pulses from hydrophone signals sampled in a centrifugal pump and analyzed their characteristics. The modified and simplified Empirical mode decomposition (EMD) algorithm was proposed for extracting cavitation pulses from strong background noise. Experimental results showed that EMD can effectively suppress noise and obtain clear cavitation pulses, facilitating the identification of the number of pulses associated with the degree of cavitation. The cavitation characteristics were modeled to predict the value of incipient cavitation. Then, we proposed a method for detecting the wear of the impeller surface. That is, the information on the impeller surface of the centrifugal pump, including the roughness of the impeller surface and its wear trends, were quantified based on the net positive suction head available of incipient cavitation. The findings indicate that the proposed technique is suitable for condition monitoring of the pump.

      • Characteristics of Pre-alloyed Powders for Diamond Tools

        Luo Xi-Yu,Ma Hong-Qiu,Kuang Xing,Huang Man,Tang Ming-Qiang 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1

        In this paper, the fundamental attributes, phase composition of three pre-alloyed powders for diamond tools by water atomization were investigated. The density, hardness, bend strength and bending modulus of their hot pressing samples were examined. The results showed that the three pre-alloyed powders have excellent low temperature sintering characteristics. The physical and mechanical properties of the samples were found to be nearly the same as those of fine cobalt powders.

      • SCIESCOPUS

        Development of a dynamic sensing system for civil revolving structures and its field tests in a large revolving auditorium

        Luo, Yaozhi,Yang, Pengcheng,Shen, Yanbin,Yu, Feng,Zhong, Zhouneng,Hong, Jiangbo Techno-Press 2014 Smart Structures and Systems, An International Jou Vol.13 No.6

        In civil engineering, revolving structures (RS) are a unique structural form applied in innovative architecture design. Such structures are able to revolve around themselves or along a certain track. However, few studies are dedicated to safety design or health monitoring of RS. In this paper, a wireless dynamic sensing system is developed for RS, and field tests toward a large revolving auditorium are conducted accordingly. At first, a wheel-rail problem is proposed: The internal force redistributes in RS, which is due to wheel-rail irregularity. Then the development of the sensing system for RS is presented. It includes system architecture, network organization, vibrating wire sensor (VWS) nodes and online remote control. To keep the sensor network identifiable during revolving, the addresses of sensor nodes are reassigned dynamically when RS position changes. At last, the system is mounted on a huge outdoor revolving auditorium. Considering the influence of the proposed problem, the RS of the auditorium has been designed conservatively. Two field tests are conducted via the sensing system. In the first test, 2000 people are invited to act as the live load. During the revolving process, data is collected from RS in three different load cases. The other test is the online monitoring for the auditorium during the official performances. In the end, the field-testing result verifies the existence of the wheel-rail problem. The result also indicates the dynamic sensing system is applicable and durable even while RS is rotating.

      • SCIESCOPUSKCI등재
      • Vascular Endothelial Growth Factor (VEGF) Gene Polymorphisms and Breast Cancer Risk in a Chinese Population

        Luo, Ting,Chen, Long,He, Ping,Hu, Qian-Cheng,Zhong, Xiao-Rong,Sun, Yu,Yang, Yuan-Fu,Tian, Ting-Lun,Zheng, Hong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4

        Vascular endothelial growth factor (VEGF) is a potent regulator of angiogenesis and thereby involved in the development and progression of solid tumours. Associations between three VEGF gene polymorphisms (-634 G/C, +936 C/T, and +1612 G/A) and breast cancer risk have been extensively studied, but the currently available results are inconclusive. Our aim was to investigate associations between three VEGF gene polymorphisms and breast cancer risk in Chinese Han patients. We performed a hospital-based case-control study including 680 female incident breast cancer patients and 680 female age-matched healthy control subjects. Polymerase chain reaction restriction fragment length polymorphism (PCR-RFLP) analysis was performed to detect the three VEGF gene polymorphisms. We observed that women carriers of +936 TT genotypes [odds ratio (OR) =0.46, 95% confidence interval (CI) = 0.28, 0.76; P=0.002] or 936 T-allele (OR=0.81, 95% CI= 0.68, 0.98; P=0.03) had a protective effect concerning the disease. Our study suggested that the +1612G/A polymorphism was unlikely to be associated with breast cancer risk. The -634CC genotype was significantly associated with high tumor aggressiveness [large tumor size (OR=2.63, 95% CI=1.15, 6.02; P=0.02) and high histologic grade (OR=1.47, 95% CI= 1.06, 2.03; P=0.02)]. The genotypes were not related with other tumor characteristics such as regional or distant metastasis, stage at diagnosis, or estrogen or progesterone receptor status. Our study revealed that the VEGF -634 G/C and +936 C/T gene polymorphisms may be associated with breast cancer in Chinese Han patients.

      • KCI등재

        Mercury Resistance and Removal Mechanisms of Pseudomonas sp. Isolated Mercury-contaminated Site in Taiwan

        Luo, Kai-Hong,Chen, Ssu-Ching,Liao, Hung-Yu Korean Society of Soil and Groundwater Environment 2016 지하수토양환경 Vol.21 No.5

        A new strain of Pseudomonas sp. was isolated from mercury (Hg)-contaminated sites in Taiwan. This bacterium removed more than 80% of Hg present in the culture medium at 12 h incubation and was chosen for further analysis of the molecular mechanisms of Hg tolerance/removal abilities in this Pseudomonas sp. We used RNA-seq, one of the next-generation sequencing methods, to investigate the transcriptomic responses of the Pseudomonas sp. exposed to 60 mg/L of Hg<sup>2+</sup>. We de novo assembled 4,963 contigs, of which 10,533 up-regulated genes and 5,451 down-regulated genes were found to be regulated by Hg. The 40 genes most altered in expression levels were associated with tolerance to Hg stress and metabolism. Functional analysis showed that some Hg-tolerant genes were related to the mer operon, sulfate uptake and assimilation, the enzymatic antioxidant system, the HSP gene family, chaperones, and metal transporters. The transcriptome were analyzed further with Gene Ontology (GO) and Cluster of Orthologous Groups (COGs) of proteins and showed diverse biological functions and metabolic pathways under Hg stress.

      • KCI등재

        Development of a dynamic sensing system for civil revolving structures and its field tests in a large revolving auditorium

        Yaozhi Luo,Yanbin Shen,Pengcheng Yang,Feng Yu,Zhouneng Zhong,Jiangbo Hong 국제구조공학회 2014 Smart Structures and Systems, An International Jou Vol.13 No.6

        In civil engineering, revolving structures (RS) are a unique structural form applied in innovative architecture design. Such structures are able to revolve around themselves or along a certain track. However, few studies are dedicated to safety design or health monitoring of RS. In this paper, a wireless dynamic sensing system is developed for RS, and field tests toward a large revolving auditorium are conducted accordingly. At first, a wheel-rail problem is proposed: The internal force redistributes in RS, which is due to wheel-rail irregularity. Then the development of the sensing system for RS is presented. It includes system architecture, network organization, vibrating wire sensor (VWS) nodes and online remote control. To keep the sensor network identifiable during revolving, the addresses of sensor nodes are reassigned dynamically when RS position changes. At last, the system is mounted on a huge outdoor revolving auditorium. Considering the influence of the proposed problem, the RS of the auditorium has been designed conservatively. Two field tests are conducted via the sensing system. In the first test, 2000 people are invited to act as the live load. During the revolving process, data is collected from RS in three different load cases. The other test is the online monitoring for the auditorium during the official performances. In the end, the field-testing result verifies the existence of the wheel-rail problem. The result also indicates the dynamic sensing system is applicable and durable even while RS is rotating.

      • KCI등재

        MOF-Derived Porous CeO2-x/C Nanorods and their Applications in Uric Acid Biosensor

        Jinbao Luo,Jiewu Cui,Yan Wang,Dongbo Yu,Yongqiang Qin,Hongmei Zheng,Yu Hong,Yong Zhang,Yucheng Wu 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.7

        Selectivity is significant to the practical applications of electrochemical biosensors in clinical and diagnostic field. In this paper, porous CeO2-x/C nanorods (NRs) derived from Ce-based metal organic framework (MOF) were synthesized and employed as substrate to construct uric acid biosensors with high sensitivity and selectivity at low working potential. The morphology, microstructures and elemental states of as-prepared samples were investigated by SEM, XRD, TEM and XPS systematically. It was found that a great amount of oxygen vacancies was introduced into the interstitial of CeO2 and nonstoichiometric CeO2/C (CeO2-x/C) nanorods based on Ce-MOF were formed under calcination in Ar atmosphere. The increased oxygen vacancies enabled the negatively shifting of the working potential towards H2O2 detection for CeO2-x/C nanorods, favoring the construction of biosensors based on the detection of H2O2. Uric biosensors based on CeO2-x/C NRs exhibited a high sensitivity of 220.0 μA · cm -2 · mM -1 and a linear range from 50 μM to 1000 μM at working potential of -0.4 V versus SCE. It also exhibited superior selectivity toward interferents coexisting with uric acid in urine due to the low working potential.

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