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Physical Properties of a New Ternary Compound RP₃Al<SUB>5</SUB> (R = rare earth)
Hiroto Fukuda,Takatsugu Koizumi,Yoshiki J. Sato,Yusei Shimizu,Ai Nakamura,Dexin Li,Yoshiya Homma,Atsushi Miyake,Dai Aoki,Masashi Tokunaga,Ryoma Kato,Masanobu Shiga,Tatsuya Kawae,Fuminori Honda 한국물리학회 2023 새물리 Vol.73 No.12
Electronic properties of a new ternary f-electron system RP ₃Al<SUB>5</SUB> (R: rare earth elements) have been investigated. RPt ₃Al<SUB>5</SUB> crystalizes in the CePt ₃Al<SUB>5</SUB>-type orthorhombic structure where R atoms form 1-dimensional chains along the b-axis. LaPt ₃Al<SUB>5</SUB> shows superconductivity below 0.4 K, while others show magnetic ordering. CePt ₃Al<SUB>5</SUB> orders antiferromagnetically below T<SUB>N</SUB> = 1.2 K with spontaneous moment and shows successive magnetic transition at T<SUB>m</SUB> = 0.9 K. The nearly divalent antiferromagnet EuPt ₃Al<SUB>5</SUB> indicates an unusual valence cross-over behavior into the nearly trivalent state under high pressure of 9 GPa. It is also found that most of RPt ₃Al<SUB>5</SUB> orders antiferromagnetically and, in some cases, shows characteristic features in magnetic suscep- tibility, where the broad maximum appears slightly above T<SUB>N</SUB>, reecting the low-dimensional nature.
Kyoichi Kato,Ken Fukunaga,Koji Kamikozuru,Shinichiro Kashiwamura,Nobuyuki Hida,Yoshio Ohda,Naohisa Takeda,Koji Yoshida,Masaki Iimuro,Yoko Yokoyama,Risa Kikuyama,Hiroto Miwa,Takayuki Matsumoto 거트앤리버 소화기연관학회협의회 2011 Gut and Liver Vol.5 No.1
Background/Aims: Infliximab (IFX), an antibody to tumor necrosis factor, (TNF)-α has effi cacy in treating Crohn’s disease (CD). However, knowledge of the potential effects of IFX on patients’ immune profi les is lacking. The purpose of this study was to reveal the immunological effects of IFX. Methods: Twenty-two patients with a CD activity index (CDAI)of 194.2±92.9 and an average duration of disease of 3.26months and 21 healthy controls were included. Patients were to have their fi rst IFX remission induction therapy with 3 infusions (5 mg/kg) at weeks 0, 2, and 6. Oral 5-aminosalicylic acid was the only ongoing medication in the patient population. Blood samples at baseline, 12 hours after the first infusion and at week 14 were labeled with anti-CD4/CD25 antibodies for immunohistochemical measurement of regulatory T-cells (Treg). Serum cytokines and chemokines were measured by suspension array and ELISA. Results:CDAI signifi cantly decreased prior to the second IFX infusion (p<0.001). Clinical remission rates were 77.3% and 91% by the second and third infusions, respectively. At baseline, interleukin (IL)-6 (p<0.03), IL-8 (p<0.03), IL-10 (p=0.050), IL-13(p<0.01), transforming growth factor-β1 (p<0.01), and ‘regulated on activation, normal T cell expressed and secreted’(RANTES) (p<0.01) were elevated in patients. After the initial IFX infusion, TNF-α (p<0.04), IL-6 (p<0.03), interferon (IFN)-γ(p<0.04), IFN-γ-inducible protein-10 (p<0.01), monocyte chemoattractant protein-1 (p<0.01), macrophage infl ammatory protein-1β (p<0.01), and RANTES (p<0.01) were decreased. IFX infusion was associated with an increase in Treg (p<0.01)and a decrease in the Th1 (IFN-γ)/Th2 (IL-4) ratio (p<0.03). Conclusions: IFX use was associated with restoration of the Th1/Th2 balance after a single infusion and seemed to promote induction of naïve Th0 lymphocytes to Treg. This knowledge should have clinical relevance.
Association of a polymorphism of BTN2A1 with dyslipidemia in East Asian populations
FUJIMAKI, TETSUO,KATO, KIMIHIKO,OGURI, MITSUTOSHI,YOHIDA, TETSURO,HORIBE, HIDEKI,YOKOI, KIYOSHI,WATANABE, SACHIRO,SATOH, KEI,AOYAGI, YUKITOSHI,TANAKA, MASASHI,YOSHIDA, HIROTO,SHINKAI, SHOJI,NOZAWA, YO Spandidos Publications 2011 Experimental and therapeutic medicine Vol.2 No.4
Nonvortical Rashba Spin Structure on a Surface with<sub>C1h</sub>Symmetry
Annese, Emilia,Kuzumaki, Takuya,Mü,ller, Beate,Yamamoto, Yuta,Nakano, Hiroto,Kato, Haruki,Araki, Atsushi,Ohtaka, Minoru,Aoki, Takashi,Ishikawa, Hirotaka,Hayashida, Takashi,Osiecki, Jacek R.,Miyamo American Physical Society 2016 Physical Review Letters Vol.117 No.1