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The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus
Harley, Isaac T. W.,Niewold, Timothy B.,Stormont, Rebecca M.,Kaufman, Kenneth M.,Glenn, Stuart B.,Franek, Beverly S.,Kelly, Jennifer A.,Kilpatrick, Jeffrey R.,Hutchings, David,Divers, Jasmin,Bruner, G Hindawi Publishing Corporation 2010 Journal of biomedicine & biotechnology Vol.2010 No.-
<P>Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by increased type I interferons (IFNs) and multiorgan inflammation frequently targeting the skin. IFN-kappa is a type I IFN expressed in skin. A pooled genome-wide scan implicated the <I>IFNK</I> locus in SLE susceptibility. We studied <I>IFNK</I> single nucleotide polymorphisms (SNPs) in 3982 SLE cases and 4275 controls, composed of European (EA), African-American (AA), and Asian ancestry. rs12553951C was associated with SLE in EA males (odds ratio = 1.93, <I>P</I> = 2.5 × 10<SUP>−4</SUP>), but not females. Suggestive associations with skin phenotypes in EA and AA females were found, and these were also sex-specific. <I>IFNK</I> SNPs were associated with increased serum type I IFN in EA and AA SLE patients. Our data suggest a sex-dependent association between <I>IFNK</I> SNPs and SLE and skin phenotypes. The serum IFN association suggests that <I>IFNK</I> variants could influence type I IFN producing plasmacytoid dendritic cells in affected skin.</P>
Digital Fashion: A systematic literature review. A perspective on marketing and communication
Noris Alice,Nobile Tekila Harley,Kalbaska Nadzeya,Cantoni Lorenzo 한국마케팅과학회 2021 Journal of Global Fashion Marketing Vol.12 No.1
Research in the overlapping area between Fashion and Information and Communication Technologies – hereafter referred to as “Digital Fashion” – is growing and attracting the interest of both academics and practitioners. However, due to the richness and heterogeneity of the involved fields, no map is already available of it. A systematic literature review was conducted in July 2019 utilizing the keywords “digital” and “fashion” in five research databases, including academic papers from 1998. This provided 491 relevant items for analysis. Three main categories to which those research papers belong to are identified: (i) Communication and Marketing (C&M); (ii) Design and Production (D&P); and (iii) Culture and Society (C&S). Each category includes two or three subcategories. This study provides an overview of the state of the art of digital fashion studies, with a focus on Communication and Marketing related research.