Physical Activity and Bladder Cancer Risk: Findings of the Japan Collaborative Cohort Study

Hang An,Keyang Liu,Kokoro Shirai,Ryo Kawasaki,Akiko Tamakoshi,Hiroyasu Iso 대한암학회 2024 Cancer Research and Treatment Vol.56 No.2

Purpose The association of physical activity with the risk of bladder cancer remains inconsistent among Asian populations. We aimed to examine the association in a large Japanese cohort.Materials and Methods In a population-based prospective cohort study, a total of 50,374 Japanese adults aged 40-79 years without a history of cancer or cardiovascular disease who had information on physical activity from self-administrated questionnaires were used for analysis. We performed Cox proportional hazard models to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) for incident bladder cancer after adjusting for several potential confounders.Results During the median 17.5 years of follow-up, 153 incident bladder cancers (116 men and 37 women) were identified. After the multivariable adjustment, HRs (95% CI) of bladder cancer concerning those with recreational sports participation of 1-2 hr/wk, 3-4 hr/wk, and 5 hr/wk and more were 0.67 (0.38-1.20), 0.79 (0.36-1.74), and 0.28 (0.09-0.89), respectively (p for trend=0.017). Compared with mostly sitting at the workplace, occupational physical activity of standing and walking were associated with a lower risk of bladder cancer (HR, 0.53 [95% CI, 0.32 to 0.85]). Hours of daily walking were not associated with the risk. The lower risk of bladder cancer was more evident for recreational sports (HR, 0.33 [95% CI, 0.10 to 1.00]), and for occupational standing and walking activity at work (HR, 0.57 [95% CI, 0.33 to 0.98]) among men.Conclusion Recreational sports participation and occupational physical activity were inversely associated with the risk of bladder cancer among Japanese, especially in men.

Swirl ratio effects on tornado vortices in relation to the Fujita scale

Hangan, H.,Kim, J.D. Techno-Press 2008 Wind and Structures, An International Journal (WAS Vol.11 No.4

Three-dimensional engineering simulations of momentum-driven tornado-like vortices are conducted to investigate the flow dynamics dependency on swirl ratio and the possible relation with real tornado Fujita scales. Numerical results are benchmarked against the laboratory experimental results of Baker (1981) for a fixed swirl ratio: S = 0.28. The simulations are then extended for higher swirl ratios up to S = 2 and the variation of the velocity and pressure flow fields are observed. The flow evolves from the formation of a laminar vortex at low swirl ratio to turbulent vortex breakdown, followed by the vortex touch down at higher swirls. The high swirl ratios results are further matched with full scale data from the Spencer, South Dakota F4 tornado of May 30, 1998 (Sarkar, et al. 2005) and approximate velocity and length scales are determined.

Downburst versus boundary layer induced wind loads for tall buildings

Kim, Jongdae,Hangan, Horia,Eric Ho, T.C. Techno-Press 2007 Wind and Structures, An International Journal (WAS Vol.10 No.5

Downbursts are transient phenomena that produce wind profiles that are distinctly different from synoptic boundary layers. Wind field data from Computational Fluid Dynamics (CFD) simulations of isolated downburst-like impinging jets, are used to investigate structural loads of tall buildings due to these high intensity winds. The base shear forces and base moments of tall buildings of heights between 120 and 250 m produced by downburst winds of various scales are compared with the forces from the equivalent boundary layer gust winds, with matched 10-metre wind velocity. The wind profiles are mainly functions of the size of the downburst and the radial distance from the centre of the storm. Wind forces due to various downburst profiles are investigated by placing the building at different locations relative to the storm center as well as varying the size of the downburst. Overall it is found that downbursts larger than approx. 2,000 m in diameter might produce governing design wind loads above those from corresponding boundary layer winds for tall buildings.

Pressure distribution and aerodynamic forces on stationary box bridge sections

Ricciardelli, Francesco,Hangan, Horia Techno-Press 2001 Wind and Structures, An International Journal (WAS Vol.4 No.5

Simultaneous pressure and force measurements have been conducted on a stationary box deck section model for two configurations (namely without and with New Jersey traffic barriers) at various angles of incidence. The mean and fluctuating aerodynamic coefficients and pressure coefficients were derived, together with their spectra and with the coherence functions between the pressures and the total aerodynamic forces. The mean aerodynamic coefficients derived from force measurements are first compared with those derived from the integration of the pressures on the deck surface. Correlation between forces and local pressures are determined in order to gain insight on the wind excitation mechanism. The influence of the angle of incidence on the pressure distribution and on the fluctuating forces is also analysed. It is evidenced how particular deck section areas are more responsible for the aerodynamic excitation of the deck.

A comparative investigation of the TTU pressure envelope. Numerical versus laboratory and full scale results

S.A. Bekele,H. Hangan 한국풍공학회 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2

A forensic study of the Lubbock-Reese downdraft of 2002

Holmes, J.D.,Hangan, H.M.,Schroeder, J.L.,Letchford, C.W.,Orwig, K.D. Techno-Press 2008 Wind and Structures, An International Journal (WAS Vol.11 No.2

This paper discusses engineering aspects of the rear-flank downdraft that was recorded near Lubbock, Texas on 4 June 2002, and produced a gust wind speed nearly equal to the design value (50-year return period) for the region. The general characteristics of the storm, and the decomposition of the time histories into deterministic 'running mean' and random turbulence components are discussed. The fluctuating wind speeds generated by the event can be represented as a dominant low-frequency 'running mean' with superimposed random turbulence of higher frequencies. Spectral and correlation characteristics of the residual turbulence are found to be similar to those of high-frequency turbulence in boundary-layer winds. However, the low-frequency components in the running-mean wind speeds are spatially homogeneous, in contrast to the low-frequency turbulence found in synoptic boundary-layer winds. With respect to transmission line design, this results in significantly higher 'span reduction factors'.

A comparative investigation of the TTU pressure envelope -Numerical versus laboratory and full scale results

Bekele, S.A.,Hangan, H. Techno-Press 2002 Wind and Structures, An International Journal (WAS Vol.5 No.2

Wind tunnel pressure measurements and numerical simulations based on the Reynolds Stress Model (RSM) are compared with full and model scale data in the flow area of impingement, separation and wake for $60^{\circ}$ and $90^{\circ}$ wind azimuth angles. The phase averaged fluctuating pressures simulated by the RSM model are combined with modelling of the small scale, random pressure field to produce the total, instantaneous pressures. Time averaged, rsm and peak pressure coefficients are consequently calculated. This numerical approach predicts slightly better the pressure field on the roof of the TTU (Texas Tech University) building when compared to the wind tunnel experimental results. However, it shows a deviation from both experimental data sets in the impingement and wake regions. The limitations of the RSM model in resolving the intermittent flow field associated with the corner vortex formation are discussed. Also, correlations between the largest roof suctions and the corner vortex "switching phenomena" are observed. It is inferred that the intermittency and short duration of this vortex switching might be related to both the wind tunnel and numerical simulation under-prediction of the peak roof suctions for oblique wind directions.

Experimental study of the loads induced by a large-scale tornado simulation on a HAWT model

Juan P. Lopez,Horia Hangan,Ashraf El Damatty 한국풍공학회 2021 Wind and Structures, An International Journal (WAS Vol.33 No.6

As wind turbine rotors increase, the overall loads and dynamic response become an important issue. This problem is augmented by the exposure of wind turbines to severe atmospheric events with unconventional flows such as tornadoes, which need specific designs not included in standards and codes at present. An experimental study was conducted to analyze the loads induced by a tornado-like vortex (TLV) on horizontal-axis wind turbines (HAWT). A large-scale tornado simulation developed in The Wind Engineering, Energy and Environment (WindEEE) Dome at Western University in Canada, the so-called Mode B Tornado, was employed as the TLV flow acting on a rigid wind turbine model under two rotor operational conditions (idling and parked) for five radial distances. It was observed that the overall forces and moments depend on the location and orientation of the wind turbine system with respect to the tornado vortex centre, as TLV are three-dimensional flows with velocity gradients in the radial, vertical, and tangential direction. The mean bending moment at the tower base was the most important in terms of magnitude and variation in relation to the position of the HAWT with respect to the core radius of the tornado, and it was highly dependent on the rotor Tip Speed Ratio (TSR).

Downburst versus boundary layer induced wind loads for tall buildings

Jongdae Kim,Horia Hangan,T.C. Eric Ho 한국풍공학회 2007 Wind and Structures, An International Journal (WAS Vol.10 No.5

Downbursts are transient phenomena that produce wind profiles that are distinctly different from synoptic boundary layers. Wind field data from Computational Fluid Dynamics (CFD) simulations of isolated downburst-like impinging jets, are used to investigate structural loads of tall buildings due to these high intensity winds. The base shear forces and base moments of tall buildings of heights between 120 and 250 m produced by downburst winds of various scales are compared with the forces from the equivalent boundary layer gust winds, with matched 10-metre wind velocity. The wind profiles are mainly functions of the size of the downburst and the radial distance from the centre of the storm. Wind forces due to various downburst profiles are investigated by placing the building at different locations relative to the storm center as well as varying the size of the downburst. Overall it is found that downbursts larger than approx. 2,000 m in diameter might produce governing design wind loads above those from corresponding boundary layer winds for tall buildings.

Finite element modelling of transmission line structures under tornado wind loading

Hamada, A.,El Damatty, A.A.,Hangan, H.,Shehata, A.Y. Techno-Press 2010 Wind and Structures, An International Journal (WAS Vol.13 No.5

The majority of weather-related failures of transmission line structures that have occurred in the past have been attributed to high intensity localized wind events, in the form of tornadoes and downbursts. A numerical scheme is developed in the current study to assess the performance of transmission lines under tornado wind load events. The tornado wind field is based on a model scale Computational Fluid Dynamic (CFD) analysis that was conducted and validated in a previous study. Using field measurements and code specifications, the CFD model data is used to estimate the wind fields for F4 and F2 full scale tornadoes. The wind forces associated with these tornado fields are evaluated and later incorporated into a nonlinear finite element three-dimensional model for the transmission line system, which includes a simulation for the towers and the conductors. A comparison is carried between the forces in the members resulting from the tornadoes, and those obtained using the conventional design wind loads. The study reveals the importance of considering tornadoes when designing transmission line structures.