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RISS 인기검색어
- 검색키워드
- 저자 : Gunasekaran Gopalakrishnan (검색결과 4 건)
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Gunasekaran Gopalakrishnan,Raja Kalayarasan,Senthil Gnanasekaran,Biju Pottakkat 한국간담췌외과학회 2020 Annals of hepato-biliary-pancreatic surgery Vol.24 No.4
Backgrounds/Aims: Additional surgical procedures are often required in patients with chronic pancreatitis (CP) related complications. The present study aims to analyze the type of additional procedures required in patients who underwent Frey’s procedure (Frey’s plus) and to compare the short-term outcomes and quality of life with patients who underwent only Frey’s procedure. Methods: Retrospective analysis of a prospectively maintained database of patients who underwent surgery for CP between January 2012 and February 2018 and completed at least one year of follow-up. Patients who underwent non-Frey’s surgical procedures were excluded. Clinical parameters, postoperative pain relief (using Izbicki pain score) and functioning scale score (EORTC QLQ C30) of patients who underwent Frey’s plus procedure and only Frey’s procedure were compared. Results: Of the 146 patients who underwent surgery for CP during the study period, 100 patients (Frey’s procedure–68, Frey’s plus procedure–32) were included in this study. Roux-en-Y hepaticojejunostomy was the commonly performed additional procedure (n=12). The demographic and clinical parameters were comparable, except for more patients with jaundice (28.1% vs. 2.9%, p=0.01) and prolonged operative time (374.6 mins vs. 326.3 mins, p=0.01) in Frey’s plus group. However, there was no significant difference in mean intraoperative blood loss, postoperative morbidity or duration of hospital stay. At median (range) follow up of 34 (12-86) months, there was no significant difference in the pain control and quality of life between two groups. Conclusions: Frey’s plus procedure for chronic pancreatitis can be safely performed wherever indicated without adversely affecting the postoperative outcome or quality of life.
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Gopalakrishnan Gunasekaran,Debasis Naik,Ashwani Gupta,Vimal Bhandari,Manigandan Kuppusamy,Gaind Kumar,Niuto S Chishi 한국간담췌외과학회 2015 한국간담췌외과학회지 Vol.19 No.1
Backgrounds/Aims: Gallbladder perforation is a rare but potentially fatal disease. We herein present our clinical experience in diagnosis and management of 32 cases of gallbladder perforation. Methods: This retrospective study was conducted with inclusion of all cases of gallbladder perforation that presented to our hospital from January 2012 to November 2014. Cases of traumatic gallbladder perforation and patients younger than 12 years of age were excluded from this study. Results: This study included 32 patients (13 males and 19 females). The mean age of patients was 55.9 years. Gallbladder perforation was most common in the 5th and 6th decade of life. The mean age of patients with type I, II, and III gallbladder perforation was 57.0 years, 57.6 years, and 49.8 years, respectively. The most common site of perforation was the fundus, followed by the body and Hartmann’s pouch (24 : 5 : 2). Most of the type I gallbladder perforations were diagnosed intraoperatively, type II gallbladder perforations were diagnosed by enhanced abdominal computed tomography, and type III gallbladder perforations were diagnosed during laparoscopic cholecystectomy converted to open cholecystectomy for cholelithiasis. Mortality was highest in patients with type I gallbladder perforation. The mean hospital stay was 10.1 days, 6.4 days, and 9.2 days in patients with type I, II, and III gallbladder perforation, respectively. The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case. Conclusions: Gallbladder perforation represents a special diagnostic and surgical challenge. Appropriate classification and management are essential.
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Arthi Gopalakrishnan,Gunasekaran Venugopal,Rajasekar Krishnan,Sakthivel Thangavel,김상재 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.30 No.-
Nanomaterials open up enormous opportunities in the areas of industrial waste water treatment andtheir application. Effective removal of toxic heavy metal ions like Pb(II), Ni(II) and Cr(VI) from pharmacywaste-effluent using graphene-oxide(GO) nanosorbents is reported here. Cr and Pb ions are completelyremoved by GO, however Ni ion trace was gradually decreased when GO concentration was increased. The concentration of GO at 70 mg removes all heavy metal ions effectively with the permissible pH of8.00 and very low conductivity of 0.027 dS/m in 100 mL effluent, studied using atomic absorptionspectroscopy. Also the adsorption isotherm models and adsorption kinetics are discussed.
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Banu, J. Rajesh,Kannah, R. Yukesh,Kavitha, S.,Gunasekaran, M.,Yeom, Ick Tae,Kumar, Gopalakrishnan Elsevier 2018 CHEMICAL ENGINEERING JOURNAL -LAUSANNE- Vol.347 No.-
<P><B>Abstract</B></P> <P>The present study highlights the options to enhance the methane potential of partially digested anaerobic sludge using disperser-induced bacterial disintegration. Floc dispersion with no biomass disintegration was achieved at a disperser-specific energy input of 9.5 kJ/kg TS. The outcomes of both sole bacterial disintegration (S-BD) and disperser-induced bacterial disintegration (D-BD) were assessed in terms of changes in lysate, biopolymer release and increase in biodegradability and methane generation. A higher lysate solubilization of about 22.4% was achieved in D-BD compared to S-BD (11.3%), indicating the efficiency of floc dispersion prior to bacterial disintegration. The biochemical methane result implies that D-BD shows higher methane potential of 0. 279 gCOD/gCOD. Considering the overall outcome achieved in this study, disperser-induced bacterial disintegration is proved to be an effective disintegration process for enhanced biodegradation and higher methane production.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Disintegration of digested sludge is a promising technique for bioenergy generation. </LI> <LI> Floc dispersion was achieved at lesser disperser input energy of 9.5 kJ/kg TS. </LI> <LI> A higher lysate solubilization of 22.4% was achieved in floc dispersed sample. </LI> <LI> Biopolymer release of floc dispersed sludge was higher (1379.8 and 394.2 mg/L) </LI> <LI> Result of methane reveals the effect of floc dispersion prior to disintegration. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
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