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( Guangyao Liu ),( Shan Li ),( Nan Chen ),( Ziyang Zhao ),( Man Guo ),( Hong Liu ),( Jie Feng ),( Dekui Zhang ),( Zhijun Yao ),( Bin Hu ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2021 Journal of Neurogastroenterology and Motility (JNM Vol.27 No.3
Background/Aims Irritable bowel syndrome (IBS) is a prevalent functional gastrointestinal disease characterized by recurrent abdominal pain and bowel dysfunction. However, the majority of previous neuroimaging studies focus on brain structure and connections but seldom on the inter-hemispheric connectivity or structural asymmetry. This study uses multi-modal imaging to investigate the abnormal changes across the 2 cerebral hemispheres in patients with IBS. Methods Structural MRI, resting-state functional MRI, and diffusion tensor imaging were acquired from 34 patients with IBS and 33 healthy controls. The voxel-mirrored homotopic connectivity, fractional anisotropy, fiber length, fiber number, and asymmetry index were calculated and assessed for group differences. In addition, we assessed their relevance for the severity of IBS. Results Compared with healthy controls, the inter-hemispheric functional connectivity of patients with IBS showed higher levels in bilateral superior occipital gyrus, middle occipital gyrus, precuneus, posterior cingulate gyrus, and angular gyrus, but lower in supplementary motor area. The statistical results showed no significant difference in inter-hemispheric anatomical connections and structural asymmetry, however negative correlations between inter-hemispheric connectivity and the severity of IBS were found in some regions with significant difference. Conclusions The functional connections between cerebral hemispheres were more susceptible to IBS than anatomical connections, and brain structure is relatively stable. Besides, the brain areas affected by IBS were concentrated in default mode network and sensorimotor network. (J Neurogastroenterol Motil 2021;27:426-435)
A Novel Image Completion Algorithm Based on Planar Features
( Mang Xiao ),( Yunxiang Liu ),( Li Xie ),( Qiaochuan Chen ),( Guangyao Li ) 한국인터넷정보학회 2018 KSII Transactions on Internet and Information Syst Vol.12 No.8
A novel image completion method is proposed that uses the advantage of planar structural information to fill corrupted portions of an image. First, in estimating parameters of the projection plane, the image is divided into several planes, and their planar structural information is analyzed. Second, in calculating the a priori probability of patch and patch offset regularity, this information is converted into a constraint condition to guide the process of filling the hole. Experimental results show that the proposed algorithm is fast and effective, and ensures the structure continuity of the damaged region and smoothness of the texture.
Huan Wang,Hongsheng Ouyang,Yaping Tian,Zhuang Liu,Xiaolei Han,Xingxing Liu,Guangyao Ran,Gangqi Wang,Daxin Pang,Xiaochun Tang 한국생물공학회 2014 Biotechnology and Bioprocess Engineering Vol.19 No.4
Nitroalkene derivatives of nitro-oleic acid(OA-NO2) regulate pluripotent cell signaling in vivo underphysiological and pathological conditions. Angiotensin IItype 1 receptor (AT1R) plays an important role in thecardiovascular system. In this study, OA-NO2 reduced theAT1R mRNA level, specifically in primary smooth musclecells, showing a 70% reduction in rat smooth muscle cells(RASMCs) and a 50% reduction in pig smooth musclecells (PASMCs). These effects were not observed in CHOcells, which highly express AT1R. The AT1R mRNA decayrate was unchanged after OA-NO2 compared with OAtreatment. Nitric oxide (NO) and peroxisome proliferatoractivatedreceptor gamma (PPARγ) did not alter thereduced effects of OA-NO2 on the AT1R mRNA level inSMCs. However, Sp1-mediated activation of the AT1Rpromoter was reduced in response to OA-NO2 in RASMCsbut not 293T cells. In addition, the nuclear factor-kappa B(NF-κB) pathway was involved in the OA-NO2-mediateddownregulation of AT1R transcription in SMCs. Takentogether, our results demonstrate that OA-NO2 specificallyinhibits AT1R mRNA expression in primary smooth musclecells via the NF-κB pathway.
Nanocomposite reinforced structures to deal with injury in physical sports
Guojiao Wang,Kun Peng,Hui Zhou,Guangyao Liu,Zhiguo Lou,Feng Pan Techno-Press 2023 Advances in nano research Vol.14 No.6
The extensive use of polymeric matrix composites in the athletic sector may be attributed to its high strength-to-weight ratio, production economy, and a longer lifespan than conventional materials. This study explored the impact of carbon nanotubes on the properties of different composite field sports equipment components. The test specimens were fabricated using the compression molding technique. The insertion of carbon nanotubes increases mechanical properties related to the process parameters to account for an improvement in the stick sections' overall performance. The dynamic response of functionally graded reinforced nanocomposite wire structure is examined in this paper on the bases of high-order hyperbolic beam theory lined to the size-dependent nonclassical nonlocal theory under the external mechanical load due to the physical activities. Finally, the impact of different parameters on the stability of nanocomposite structures is discussed in detail.