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Dark Matter Search in a Proton Beam Dump with MiniBooNE
Aguilar-Arevalo, A. A.,Backfish, M.,Bashyal, A.,Batell, B.,Brown, B. C.,Carr, R.,Chatterjee, A.,Cooper, R. L.,deNiverville, P.,Dharmapalan, R.,Djurcic, Z.,Ford, R.,Garcia, F. G.,Garvey, G. T.,Grange, American Physical Society 2017 Physical Review Letters Vol.118 No.22
Dark matter search in nucleon, pion, and electron channels from a proton beam dump with MiniBooNE
Aguilar-Arevalo, A. A.,Backfish, M.,Bashyal, A.,Batell, B.,Brown, B. C.,Carr, R.,Chatterjee, A.,Cooper, R. L.,deNiverville, P.,Dharmapalan, R.,Djurcic, Z.,Ford, R.,Garcia, F. G.,Garvey, G. T.,Grange, American Physical Society 2018 Physical Review D Vol.98 No.11
Lopez-Soto, M.A.,Rivera-Mendez, C.R.,Aguilar-Hernandez, J.A.,Barreras, A.,Calderon-Cortes, J.F.,Plascencia, A.,Davila-Ramos, H.,Estrada-Angulo, A.,Valdes-Garcia, Y.S. Asian Australasian Association of Animal Productio 2014 Animal Bioscience Vol.27 No.2
As a result of the cost of grains, the replacement of grains by co-products (i.e. DDGS) in feedlot diets is a common practice. This change produces diets that contain a lower amount of starch and greater amount of fibre. Hypothetically, combining feed grade urea (U) with slow release urea (Optigen) in this type of diet should elicit a better synchrony between starch (high-rate of digestion) and fibre (low-rate of digestion) promoting a better microbial protein synthesis and ruminal digestion with increasing the digestible energy of the diet. Four cannulated Holstein steers ($213{\pm}4$ kg) were used in a $4{\times}4$ Latin square design to examine the combination of Optigen and U in a finishing diet containing different starch:acid detergent fibre ratios (S:F) on the characteristics of digestive function. Three S:F ratios (3.0, 4.5, and 6.0) were tested using a combination of U (0.80%) and Optigen (1.0%). Additionally, a treatment of 4.5 S:F ratio with urea (0.80% in ration) as the sole source of non-protein nitrogen was used to compare the effect of urea combination at same S:F ratio. The S:F ratio of the diet was manipulated by replacing the corn grain by dried distillers grain with solubles and roughage. Urea combination did not affect ruminal pH. The S:F ratio did not affect ruminal pH at 0 and 2 h post-feeding but, at 4 and 6 h, the ruminal pH decreased as the S:F ratio increased (linear, p<0.05). Ruminal digestion of OM, starch and feed N were not affected by urea combination or S:F ratio. The urea combination did not affect ADF ruminal digestion. ADF ruminal digestion decreased linearly (p = 0.02) as the S:F ratio increased. Compared to the urea treatment (p<0.05) and within the urea combination treatment (quadratic, p<0.01), the flow of microbial nitrogen (MN) to the small intestine and ruminal microbial efficiency were greater for the urea combination at a S:F ratio of 4.5. Irrespective of the S:F ratio, the urea combination improved (2.8%, p = 0.02) postruminal N digestion. As S:F ratio increased, OM digestion increased, but ADF total tract digestion decreased. The combination of urea at 4.5 S:F improved (2%, p = 0.04) the digestible energy (DE) more than expected. Combining urea and Optigen resulted in positive effects on the MN flow and DE of the diet, but apparently these advantages are observed only when there is a certain proportion of starch:ADF in the diet.
An Approach to Art Collections Management and Content-based Recovery
De Celis Herrero, Concepcion Perez,Alvarez, Jaime Lara,Aguilar, Gustavo Cossio,Garcia, Maria Josefa Somodevilla Korea Information Processing Society 2011 Journal of information processing systems Vol.7 No.3
This study presents a comprehensive solution to the collection management, which is based on the model for Cultural Objects (CCO). The developed system manages and spreads the collections that are safeguarded in museums and galleries more easily by using IT. In particular, we present our approach for a non-structured search and recovery of the objects based on the annotation of artwork images. In this methodology, we have introduced a faceted search used as a framework for multi-classification and for exploring/browsing complex information bases in a guided, yet unconstrained way, through a visual interface.
Salcedo, Mauricio,Pina-Sanchez, Patricia,Vallejo-Ruiz, Veronica,Monroy-Garcia, Alberto,Aguilar-Lemarroy, Adriana,Cortes-Gutierrez, Elva I.,Santos-Lopez, Gerardo,Montoya-Fuentes, Hector,Grijalva, Renan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: The aetiological relationship between human papillomavirus (HPV) infection and cervical cancer (CC) is widely accepted. Our goal was to determine the prevalence of HPV types in Mexican women attending at the Mexican Institute for Social Security from different areas of Mexico. Materials and Methods: DNAs from 2,956 cervical samples were subjected to HPV genotyping: 1,020 samples with normal cytology, 931 with low-grade squamous intraepithelial lesions (LGSIL), 481 with high grade HGSIL and 524 CC. Results: Overall HPV prevalence was 67.1%. A total of 40 HPV types were found; HPV16 was detected in 39.4% of the HPV-positive samples followed by HPV18 at 7.5%, HPV31 at 7.1%, HPV59 at 4.9%, and HPV58 at 3.2%. HPV16 presented the highest prevalence both in women with altered or normal cytology and HPV 18 presented a minor prevalence as reported worldwide. The prevalence ratio (PR) was calculated for the HPV types. The analysis of PR showed that HPV16 presents the highest association with CC, HPV 31, -33, -45, -52 and -58 also demonstrating a high association. Conclusions: The most prevalent HPV types in cervical cancer samples were -16, -18, -31, but it is important to note that we obtained a minor prevalence of HPV18 as reported worldwide, and that HPV58 and -52 also were genotypes with an important prevalence in CC samples. Determination of HPV genotypes is very important in order to evaluate the impact of vaccine introduction and future cervical cancer prevention strategies.
Function of the DEMETER DNA glycosylase in the Arabidopsis thaliana male gametophyte.
Schoft, Vera K,Chumak, Nina,Choi, Yeonhee,Hannon, Mike,Garcia-Aguilar, Marcelina,Machlicova, Adriana,Slusarz, Lucyna,Mosiolek, Magdalena,Park, Jin-Sup,Park, Guen Tae,Fischer, Robert L,Tamaru, Hisashi National Academy of Sciences 2011 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF Vol.108 No.19
<P>In double fertilization, the vegetative cell of the male gametophyte (pollen) germinates and forms a pollen tube that brings to the female gametophyte two sperm cells that fertilize the egg and central cell to form the embryo and endosperm, respectively. The 5-methylcytosine DNA glycosylase DEMETER (DME), expressed in the central cell, is required for maternal allele demethylation and gene imprinting in the endosperm. By contrast, little is known about the function of DME in the male gametophyte. Here we show that reduced transmission of the paternal mutant dme allele in certain ecotypes reflects, at least in part, defective pollen germination. DME RNA is detected in pollen, but not in isolated sperm cells, suggesting that DME is expressed in the vegetative cell. Bisulfite sequencing experiments show that imprinted genes (MEA and FWA) and a repetitive element (Mu1a) are hypomethylated in the vegetative cell genome compared with the sperm genome, which is a process that requires DME. Moreover, we show that MEA and FWA RNA are detectable in pollen, but not in isolated sperm cells, suggesting that their expression occurs primarily in the vegetative cell. These results suggest that DME is active and demethylates similar genes and transposons in the genomes of the vegetative and central cells in the male and female gametophytes, respectively. Although the genome of the vegetative cell does not participate in double fertilization, its DME-mediated demethylation is important for male fertility and may contribute to the reconfiguration of the methylation landscape that occurs in the vegetative cell genome.</P>