http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Toshihiko Tomita,Hirokazu Fukui,Daisuke Morishita,Ayako Maeda,Yutaka Makizaki,Yoshiki Tanaka,Hiroshi Ohno,Tadayuki Oshima,Hiroto Miwa 대한소화기 기능성질환∙운동학회 2023 Journal of Neurogastroenterology and Motility (JNM Vol.29 No.1
Background/AimsDiarrhea-predominant irritable bowel syndrome (IBS-D)-like symptoms frequently occur in patients with quiescent Crohn’s disease (CD). To investigate the factors underlying IBS-D-like symptoms in patients with quiescent CD, we performed a comprehensive analysis of the clinical features and intestinal environment in those patients. MethodsWe performed a prospective observational study of 27 patients with quiescent CD (CD activity index [CDAI] ≤ 150; C-reactive protein ≤ 0.3 mg/dL). The presence and severity of IBS-D-like symptoms, health-related quality of life, disease-specific quality of life, and status of depression and anxiety were evaluated. The level of intestinal permeability, fecal calprotectin and organic acids and the profiles of gut microbiome were analyzed. ResultsTwelve of the 27 patients with quiescent CD (44.4%) had IBS-like symptoms, and these patients showed a significantly higher CDAI, IBS severity index and anxiety score than those without. The inflammatory bowel disease questionnaire score was significantly lower in the patients with IBS-D-like symptoms. There were no significant differences in small intestinal/colonic permeability or the levels of organic acids between the patients with and without IBS-D-like symptoms. Fusicatenibacter was significantly less abundant in the patients with IBS-D-like symptoms whereas their fecal calprotectin level was significantly higher (384.8 ± 310.6 mg/kg) than in patients without (161.0 ± 251.0 mg/kg). The receiver operating characteristic curve constructed to predict IBS-D-like symptoms in patients with quiescent CD using the fecal calprotectin level (cutoff, 125 mg/kg) showed a sensitivity and specificity of 73.3% and 91.7%, respectively. ConclusionMinimal inflammation is closely associated with the development of IBS-D-like symptoms in patients with quiescent CD.
Kitano Tomoko,Kawakami Mamoru,Ishimoto Yuyu,Teraguchi Masatoshi,Fukui Daisuke,Matsuoka Toshiko,Nakagawa Yukihiro 대한척추외과학회 2021 Asian Spine Journal Vol.15 No.4
Study DesignCross-sectional study.PurposeThe purpose of this study was to investigate the effects of psychotic symptoms such as anxiety and fear in patients undergoing lumbar spinal canal stenosis.Overview of LiteratureRecently, patients with spinal disorders have not only been evaluated objectively for their disease, but also for patient-reported outcomes (PROs) including pain, physical function, and quality of life (PROs). Since depression has been previously associated with surgical outcomes, several studies have indicated that psychological problems may worsen the effects of pain and make treatment increasingly difficult.MethodsA questionnaire survey was conducted on 346 lumbar spinal stenosis (LSS) patients who visited our hospital from 2010 to 2016. The content of the questionnaire included questions on PROs (Japanese Orthopedic Association Back Pain Evaluation Questionnaire [JOABPEQ], Roland–Morris Disability Questionnaire, Japanese version [RDQ], and Zurich Claudication Questionnaire [ZCQ]) and psychological evaluation (Self-rating Questionnaire of Depression, Pain Catastrophizing Scale, Pain Anxiety Symptoms Scale-20 [PASS-20], Hospital Anxiety and Depression Scale, and Brief Scale for Psychiatric Problems in Orthopedic Patients). IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) was used for statistical analysis and Spearman’s rank correlation coefficient, Mann-Whitney U-test, and multiple regression analysis were also performed.ResultsNo significant correlations were found between psychological factors and PROs (r>0.4). However, patients with abnormal scores for preoperative psychological items on questionnaires other than the PASS-20 also had lower scores for lumbar spine dysfunction and social life dysfunction on the JOABPEQ subscales along with higher scores for the RDQ, symptom severity and physical function on the ZCQ compared to those with normal psychological scores (p<0.05).ConclusionsPreoperative psychological factors in patients with LSS were associated with their RDQ, JOABEPQ, and ZCQ scores. These results suggest that factors such as catastrophic thoughts on pain, anxiety, depression, and fear that may affect the clinical outcomes in patients with LSS should be evaluated before surgery to facilitate psychological interventions.
Hidetoshi Sano,TOMOYA AMATSUTSU,TORU KONDO,KEICHIRO NAKAMICHI,MITSUYOSHI YAMAGISHI,DAISUKE ISHIHARA,SHINKI OYABU,HIDEHIRO KANEDA,KENGO TACHIHARA,YASUO FUKUI 한국천문학회 2017 天文學論叢 Vol.32 No.1
We present a comparative study of CO and polycyclic aromatic hydrocarbon (PAH) emission toward a region including the massive star-forming regions of NGC 6334 and NGC 6357. We use the NANTEN $^{12}$CO($J$=1--0) data and the $AKARI$ 9 $\mu$m All-Sky diffuse map in order to evaluate the calibration accuracy of the $AKARI$ data. We confirm that the overall CO distribution shows a good spatial correspondence with the PAH emission, and their intensities exhibit a good power-law correlation with a spatial resolution down to 4$\rq{}$ over the region of 10$^\circ$$\times$10$^\circ$. We also reveal poorer correlation for small scale structures between the two quantities toward NGC 6357, due to strong UV radiation from local sources. Larger scatter in the correlation toward NGC 6357 indicates higher ionization degree and/or PAH excitation than that of NGC 6334.
A Planetary Microlensing Event with an Unusually Red Source Star: MOA-2011-BLG-291
Bennett, David P.,Udalski, Andrzej,Bond, Ian A.,Suzuki, Daisuke,Ryu, Yoon-Hyun,Abe, Fumio,Barry, Richard K.,Bhattacharya, Aparna,Donachie, Martin,Fukui, Akihiko,Hirao, Yuki,Kawasaki, Kohei,Kondo, Iona American Astronomical Society 2018 The Astronomical journal Vol.156 No.3