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        Pyroprocess Experiments at ENEA Laboratories

        Giorgio DE ANGELIS,Elio BAICCHI,Mauro CAPONE,Carlo FEDELI,Massimo SEPIELLI,Giuliano TIRANTI,Mirko DA ROS,Francesca GIACOBBO,Marco GIOLA,Elena MACERATA,Mario MARIANI 한국방사성폐기물학회 2015 방사성폐기물학회지 Vol.13 No.S

        A new facility, known as Pyrel III, has been installed at ENEA laboratories for pyrochemical process studies under inactive conditions. It is a pilot plant which allows electrorefining and electroreduction experiments to be conducted on simulated fuel. The main component of the plant is a zirconia crucible. The crucible is heated by a furnace which is supported in an externally water-cooled well under the floor of a steel glove-box, where an argon atmosphere is maintained by a continual purge of about 10 L·min-1. The vessel is loaded with LiCl-KCl eutectic salt (59-41 mol%) and is currently operated at 460 °C. Several improvements on Pyrel II (the previous operating plant) have been introduced into Pyrel III. They are described in detail, together with the results from the first experimental campaign which used lanthanum metal. Moreover, studies about the treatment of chloride salt wastes from pyroprocesses have been conducted in parallel. They follow two main routes: on one hand, a matrix termed sodalite, a naturally occurring mineral containing chlorine, has been synthesized from a mix of nepheline, simulated exhausted salts and glass frit; on the other hand, a novel method proposed by Korea Atomic Energy Research Institute (KAERI) is under assessment. The final waste forms have been fully characterized with the support of the Politechnique of Milan, by means of density measurements, thermal analysis, and stereomicroscopy observations, FTIR, XRD, and RAMAN spectra, as well as leach tests under static conditions.

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        Survival Nomograms after Curative Neoadjuvant Chemotherapy and Radical Surgery for Stage IB2-IIIB Cervical Cancer

        Claudia Marchetti,Francesca De Felice,Anna Di Pinto,Alessia Romito,Angela Musella,Innocenza Palaia,Marco Monti,Vincenzo Tombolini,Ludovico Muzii,PierLuigi Benedetti Panici 대한암학회 2018 Cancer Research and Treatment Vol.50 No.3

        Purpose The purpose of this study was to develop nomograms for predicting the probability of overall survival (OS) and progression-free survival (PFS) in locally advanced cervical cancer treated with neoadjuvant chemotherapy and radical surgery. Materials and Methods Nomograms to predict the 5-year OS rates and the 2-year PFS rates were constructed. Calibration plots were constructed, and concordance indices were calculated. Evaluated variables were body mass index, age, tumor size, tumor histology, grading, lymphovascular space invasion, positive parametria, and positive lymph nodes. Results In total 245 patients with locally advanced cervical cancer who underwent neoadjuvant chemotherapy and radical surgery were included for the construction of the nomogram. The 5-year OS and PFS were 72.6% and 66%, respectively. Tumor size, grading, and parametria status affected the rate of OS, whereas tumor size and positive parametria were the main independent PFS prognostic factors. Conclusion We constructed a nomogram based on clinicopathological features in order to predict 2-year PFS and 5-year OS in locally advanced cervical cancer primarily treated with neoadjuvant chemotherapy followed by radical surgery. This tool might be particularly helpful for assisting in the follow-up of cervical cancer patients who have not undergone concurrent chemoradiotherapy.

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        In-hospital mortality in the emergency department: clinical and etiological differences between early and late deaths among patients awaiting admission

        Gabriele Valli,Elisabetta Galati,Francesca De Marco,Chiara Bucci,Paolo Fratini,Elisa Cennamo,Carlo Ancona,Nicola Volpe,Maria Pia Ruggieri 대한응급의학회 2021 Clinical and Experimental Emergency Medicine Vol.8 No.4

        Objective Given that there are no studies on diseases that occur by waiting for hospitalization, we aimed to evaluate the main causes of death in the emergency room (ER) and their relationship with overcrowding. Methods Patients who died in the ER in the past 2 years (pediatrics and trauma victims excluded) were divided into two groups: patients who died within 6 hours of arrival (emergency department [ED] group) and patients who died later (LD group). We compared the causes of death, total vital signs, diagnostic tests performed, and therapy between the groups. We assessed for possible correlation between the number of monthly deaths per group and four variables of overcrowding: number of patients treated per month, waiting time before medical visit (W-Time), mean intervention time (I-Time), and number of patients admitted to the ward per month (NPA). Results During the two years, 175 patients had died in our ER (52% in ED group and 48% in LD group). The total time spent in the ER was, respectively, 2.9±0.2 hours for ED group and 17.9± 1.5 hours for LD group. The more frequent cause of death was cardiovascular syndrome (30%) in ED group and sepsis (27%) and acute respiratory failure (27%) in LD group. Positive correlations between number of monthly deaths and W-Time (R2 0.51, P< 0.0001), and NPA (R2 0.37, P

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