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Use of Amplatzer Vascular Plug to Treat a Biliary Cutaneous Fistula
Anna Maria Ierardi,Federico Fontana,Monica Mangini,Filippo Piacentino,Eugenio Cocozza,Emila Frankowska,Chiara Floridi,Gianpaolo Carrafiello 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.5
Several substances have been used in an attempt to sclerose biliary ducts associated with persistent biliary-cutaneous fistula (BCF). The AMPLATZER Vascular Plug (AVP; AGA Medical, USA) system is a recently developed endovascular occlusion device, introduced as an alternative to permanent embolic materials (metallic coils or acrylic glue), in the occlusion of large and medium-calibre arteries and veins. We report a successful use of the AVP to embolize BCF, developed after the removal of an internal-external biliary drainage.
Soluble ST2 Levels and Left Ventricular Structure and Function in Patients With Metabolic Syndrome
Vera Celic,Anka Majstorovic,Biljana Pencic-Popovic,Aleksandra Sljivic,Natalia Lopez-Andres,Ignacio Roy,Elena Escribano,Maite Beunza,Amaia Melero,Federico Floridi,Laura Magrini,Rossella Marino,Gerardo 대한진단검사의학회 2016 Annals of Laboratory Medicine Vol.36 No.6
Background: A biomarker that is of great interest in relation to adverse cardiovascular events is soluble ST2 (sST2), a member of the interleukin family. Considering that metabolic syndrome (MetS) is accompanied by a proinflammatory state, we aimed to assess the relationship between sST2 and left ventricular (LV) structure and function in patients with MetS. Methods: A multicentric, cross-sectional study was conducted on180 MetS subjects with normal LV ejection fraction as determined by echocardiography. LV hypertrophy (LVH) was defined as an LV mass index greater than the gender-specific upper limit of normal as determined by echocardiography. LV diastolic dysfunction (DD) was assessed by pulse-wave and tissue Doppler imaging. sST2 was measured by using a quantitative monoclonal ELISA assay. Results: LV mass index (β=0.337, P<0 .001, linear regression) was independently associated with sST2 concentrations. Increased sST2 was associated with an increased likelihood of LVH [Exp (B)=2.20, P=0.048, logistic regression] and increased systolic blood pressure [Exp (B)=1.02, P=0.05, logistic regression]. Comparing mean sST2 concentrations (adjusted for age, body mass index, gender) between different LV remodeling patterns, we found the greatest sST2 level in the group with concentric hypertrophy. There were no differences in sST2 concentration between groups with and without LV DD. Conclusions: Increased sST2 concentration in patients with MetS was associated with a greater likelihood of exhibiting LVH. Our results suggest that inflammation could be one of the principal triggering mechanisms for LV remodeling in MetS.