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( Siti Fatimah ),( Lilis Surienty ),( Yusliza Mohd Yusoff ) 한국정책학회 2016 한국정책학회 추계학술발표논문집 Vol.2016 No.-
The issue of brain drain was the basis for this study. Countries, especially developing like Malaysia, have felt insecure when their talented professinals show an outflow movement out of the country. Losing this skilled workforee will bring difficulties for the home country in achieving high per capita income thus undermining the economic development. In every nation, the government play an important role to create programmes and policy in order to attract talent. As for that, Malaysian government hired TalentCorp alaysia Berhad (TalentCorp) to develop strategies and implement more effective action plan to alleviate the brain drain issues in Malaysia. Returning Expert Programme(REP) was one of the program introduced to attract and facilitate the return of experienced Malaysian Professionals from abroad. Due to that, this article aims to add knowledge on the effectiveness of government programme and how it influences the intention to repatriate among self-initiated expatriates (SIEs). A total of 130 responses were gathered from Malaysian self-initiated expatriates who are currently abroad. The data were then analysed The data were then analysed using structural equation modelling to confirm the proposed relationship. The results showed that government programme was not the causal factors of the SIE`s inention to repatriate. Finding indicate that the government has only a limited control over the expatriate`s decision. However, the government play a role in providing incentives or aid of repatriation for the self-initiated expatriates to ease the repatriation process. Thus, the implication of the findings was pres ented and recommendation were made for future studies.
Yehya, Ashwaq Hamid,Yusoff, Narazah Mohd,Khalid, Imran A.,Mahsin, Hakimah,Razali, Ruzzieatul Akma,Azlina, Fatimah,Mohammed, Kamil Sheikh,Ali, Syed A. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Background: To assess the diagnostic potential of tumor-associated high molecular weight DNA in stool samples of 32 colorectal cancer (CRC) patients compared to 32 healthy Malaysian volunteers by means of polymerase chain reaction (PCR). Methods: Stool DNA was isolated and tumor-associated high molecular weight DNA (1.476 kb fragment including exons 6-9 of the p53 gene) was amplified using PCR and visualized on ethidium bromide-stained agarose gels. Results: Out of 32 CRC patients, 18 were positive for the presence of high molecular weight DNA as compared to none of the healthy individuals, resulting in an overall sensitivity of 56.3% with 100% specificity. Out of 32 patients, 23 had tumor on the left side and 9 on the right side, 16 and 2 being respectively positive. This showed that high molecular weight DNA was significantly (p = 0.022) more detectable in patients with left side tumor (69.6% vs 22.2%). Out of 32 patients, 22 had tumors larger than 1.0 cm, 18 of these (81.8%) being positive for long DNA as compared to not a single patient with tumor size smaller than 1.0 cm (p <0.001). Conclusion: We detected CRC-related high molecular weight p53 DNA in stool samples of CRC patients with an overall sensitivity of 56.3% with 100% specificity, with a strong tumor size dependence.
Khong, Nicholas M.H.,Foo, Su Chern,Yau, Sook Kun,Chan, Kim Wei,Yusoff, Fatimah Md. The Korean Society of Fisheries and Aquatic Scienc 2022 Fisheries and Aquatic Sciences Vol.25 No.4
Jellyfish is an emerging aquaculture species, farmed for Oriental cuisines and nutraceutical ingredients. This study aimed to examine antioxidative and antimicrobial potentials of various fractions of the jellyfish, Acromitus hardenbergi. The bell and oral arms of the jellyfish were sequentially extracted with petroleum ether (PE), dichloromethane (DCM), chloroform (CHCl<sub>3</sub>), methanol (MeOH), and water (H<sub>2</sub>O) to extract its bioactive in an increasing polarity gradient. Test fractions were assayed for antiradical activities using electron spin resonance spectrometry, β-carotene-linoleate model and Folin-Ciocalteu assay; and antimicrobial activity against 2 Gram-negative bacteria, 4 Gram-positive bacteria and 2 fungal species using the disc diffusion assay. All fractions were also subjected to Fourier Transform Infrared (FTIR) analysis to identify types of functional groups present. It was found that the hydrophilic extracts (H<sub>2</sub>O fractions) possessed the most effective radical scavenging activity (p < 0.05) while the lipophilic extracts (PE fractions) the most active antimicrobial activity, especially against Gram-positive bacteria (p < 0.05). Total oxidation substrates content was found to be highest in the PE fractions of jellyfish bell and oral arms (p < 0.05). FTIR data showed that the H<sub>2</sub>O and MeOH fractions contains similar functional groups including -OH, -C=O, -N-H and -S=O groups, while the PE, DCM, and CHCl<sub>3</sub> fractions, the -CH<sub>3</sub>, -COOH groups. This study showed that A. hardenbergi contains antioxidants and antimicrobials, thereby supporting the traditional claim of the jellyfish as an anti-aging and health-promoting functional food. Bioassay-guided fractionation approach serves as a critical milestone for the strategic screening, purification, and elucidation of therapeutically significant actives from jellyfish.