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      • DRAMA: An Architecture for Accelerated Processing Near Memory

        Farmahini-Farahani, Amin,Jung Ho Ahn,Morrow, Katherine,Nam Sung Kim IEEE 2015 IEEE computer architecture letters Vol.14 No.1

        <P>Improving energy efficiency is crucial for both mobile and high-performance computing systems while a large fraction of total energy is consumed to transfer data between storage and processing units. Thus, reducing data transfers across the memory hierarchy of a processor (i.e., off-chip memory, on-chip caches, and register file) can greatly improve the energy efficiency. To this end, we propose an architecture, DRAMA, that 3D-stacks coarse-grain reconfigurable accelerators (CGRAs) atop off-chip DRAM devices. DRAMA does not require changes to the DRAM device architecture, apart from through-silicon vias (TSVs) that connect the DRAM device's internal I/O bus to the CGRA layer. We demonstrate that DRAMA can reduce the energy consumption to transfer data across the memory hierarchy by 66-95 percent while achieving speedups of up to 18× over a commodity processor.</P>

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        Low-dose intravenous ketamine versus intravenous ketorolac in pain control in patients with acute renal colic in an emergency setting: a double-blind randomized clinical trial

        Sotoodehnia, Mehran,Farmahini-Farahani, Mozhgan,Safaie, Arash,Rasooli, Fatemeh,Baratloo, Alireza The Korean Pain Society 2019 The Korean Journal of Pain Vol.32 No.2

        Background: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). Methods: This is a double-blind randomized clinical trial. The initial pain severity was assessed using the numerical rating scale (NRS). Then, ketamine or ketorolac was administered intravenously at a dose of 0.6 mg/kg and 30 mg respectively. The pain severity and adverse drug reactions were recorded 5, 15, 30, 60, and 120 min thereafter. Results: The data of 62 subjects in the ketamine group and 64 patients in the ketorolac group were analyzed. The mean age of the patients was $34.2{\pm}9.9$ and $37.9{\pm}10.6\;years$ in the ketamine and ketorolac group, respectively. There was no significant difference in the mean NRS scores at each time point, except for the 5 min, between the two groups. Despite a marked decrease in pain severity in the ketamine group from drug administration at the 5 min, a slight increase in pain was observed from the 5 min to the 15 min. The rate of adverse drug reactions, including dizziness (P = 0.001), agitation (P = 0.002), increased systolic blood pressure (> 140 mmHg), and diastolic blood pressure (> 90 mmHg) was higher in the ketamine group. Conclusions: Low dose ketamine is as effective as ketorolac in pain management in patients with renal colic presenting to the ED. However, it is associated with a higher rate of adverse drug reactions.

      • KCI등재

        Low-dose intravenous ketamine versus intravenous ketorolac in pain control in patients with acute renal colic in an emergency setting: a double-blind randomized clinical trial

        Mehran Sotoodehnia,Mozhgan Farmahini-Farahani,Arash Safaie,Fatemeh Rasooli,Alireza Baratloo 대한통증학회 2019 The Korean Journal of Pain Vol.32 No.2

        Background: This study was conducted to compare the effectiveness of low-dose ketamine versus ketorolac in pain control in patients with acute renal colic presenting to the emergency department (ED). Methods: This is a double-blind randomized clinical trial. The initial pain severity was assessed using the numerical rating scale (NRS). Then, ketamine or ketorolac was administered intravenously at a dose of 0.6 mg/kg and 30 mg respectively. The pain severity and adverse drug reactions were recorded 5, 15, 30, 60, and 120 min thereafter. Results: The data of 62 subjects in the ketamine group and 64 patients in the ketorolac group were analyzed. The mean age of the patients was 34.2 ± 9.9 and 37.9 ± 10.6 years in the ketamine and ketorolac group, respectively. There was no significant difference in the mean NRS scores at each time point, except for the 5 min, between the two groups. Despite a marked decrease in pain severity in the ketamine group from drug administration at the 5 min, a slight increase in pain was observed from the 5 min to the 15 min. The rate of adverse drug reactions, including dizziness (P = 0.001), agitation (P = 0.002), increased systolic blood pressure (> 140 mmHg), and diastolic blood pressure (> 90 mmHg) was higher in the ketamine group. Conclusions: Low dose ketamine is as effective as ketorolac in pain management in patients with renal colic presenting to the ED. However, it is associated with a higher rate of adverse drug reactions.

      • Near-DRAM Acceleration with Single-ISA Heterogeneous Processing in Standard Memory Modules

        Asghari-Moghaddam, Hadi,Farmahini-Farahani, Amin,Morrow, Katherine,Jung Ho Ahn,Nam Sung Kim IEEE 2016 IEEE micro Vol.36 No.1

        <P>THIS ARTICLE PRESENTS A NEAR-DRAM ACCELERATION (NDA) ARCHITECTURE IN WHICH LIGHTWEIGHT PROCESSORS (LWPS) WITH THE SAME ISA AS THEIR HOST PROCESSOR ARE 3D-STACKED ATOP COMMODITY DRAM DEVICES IN A STANDARD MEMORY MODULE TO EFFICIENTLY PROCESS DATA. EXPERIMENTS DEMONSTRATE THAT, ON AVERAGE, THE AUTHORS' NDA-BASED SYSTEM CONSUMES ALMOST 65 PERCENT LESS ENERGY AT NEARLY TWO TIMES HIGHER PERFORMANCE THAN THE BASELINE SYSTEM.</P>

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