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Murat Cakir, Safak Ersoz,Ulas Emre Akbulut 대한소아소화기영양학회 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.1
We report a pediatric patient admitted with abdominal pain, diffuse lower extremity edema and watery diarrhea for two months. Laboratory findings including complete blood count, serum albumin, lipid and immunoglobulin levels were compatible with protein losing enteropathy. Colonoscopic examination revealed diffuse ulcers with smooth raised edge (like "punched out holes") in the colon and terminal ileum. Histopathological examination showed active colitis, ulcerations and inclusion bodies. Immunostaining for cytomegalovirus was positive. Despite supportive man-agement, antiviral therapy, the clinical condition of the patient worsened and developed disseminated cytomegalovi-rus infection and the patient died. Protein losing enteropathy and disseminated cytomegalovirus infection a present-ing of feature in steroid-naive patient with inflammatory bowel disease is very rare. Hypogammaglobulinemia asso-ciated with protein losing enteropathy in Crohn's disease may predispose the cytomegalovirus infection in previously healthy children.
Cakir, Murat,Ersoz, Safak,Akbulut, Ulas Emre The Korean Society of Pediatric Gastroenterology 2015 Pediatric gastroenterology, hepatology & nutrition Vol.18 No.1
We report a pediatric patient admitted with abdominal pain, diffuse lower extremity edema and watery diarrhea for two months. Laboratory findings including complete blood count, serum albumin, lipid and immunoglobulin levels were compatible with protein losing enteropathy. Colonoscopic examination revealed diffuse ulcers with smooth raised edge (like "punched out holes") in the colon and terminal ileum. Histopathological examination showed active colitis, ulcerations and inclusion bodies. Immunostaining for cytomegalovirus was positive. Despite supportive management, antiviral therapy, the clinical condition of the patient worsened and developed disseminated cytomegalovirus infection and the patient died. Protein losing enteropathy and disseminated cytomegalovirus infection a presenting of feature in steroid-naive patient with inflammatory bowel disease is very rare. Hypogammaglobulinemia associated with protein losing enteropathy in Crohn's disease may predispose the cytomegalovirus infection in previously healthy children.
Silan based paraoxon memories onto QCM electrodes
Ebru Birlik Ozkutuk,Sibel Emir Diltemiz,Elif Ozalp,Arzu Ersoz,Rıdvan Say 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.6
In this study, a novel quartz crystal microbalance (QCM) based on the modification of paraoxon-imprinted polymer onto a QCM with a high selectivity and sensitivity has been developed for the determination of paraoxon. The QCM sensor has characterized using AFM and ellipsometer. The performance of the QCM sensor has evaluated and presented good reproducibility, shorter response time (20 min), wider linear range (0.02–10 mM) and low detection limit (0.02 mM). The results have shown that the selectivity of QCM sensor has found as being very high in the presence of parathion which is similar in structure with paraoxon.
Associations between Adiponectin and Two Different Cancers: Breast and Colon
Gulcelik, Mehmet Ali,Colakoglu, Kadri,Dincer, Halil,Dogan, Lutfi,Yenidogan, Erdinc,Gulcelik, Nese Ersoz Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1
Objectives: Breast and colon cancer are neoplasms well known to be related to obesity. Adiponectin, a protein that increases in obesity, seems to be involved in the relationship but clinical data are limited. Methods: In this study, we therefore evaluated the serum adiponectin levels in 87 breast and 27 colon cancer patients and assessed the relation with BMI, menopausal status, receptor status and stage of disease. Results: Serum adiponectin levels were lower in cancer cases ($8583{\pm}2095$ ng/ml for breast cancer, $9513{\pm}2276$ for colon cancer) than in controls ($13905{\pm}3263$). Conclusion: A low serum adiponectin level may be associated with both breast and colon cancer, and that this association is not statistically significant for either receptor or menopausal status in breast cancer groups.