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RISS 인기검색어
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- 저자 : Elemam Mahmoud (검색결과 2 건)
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Alaa A. Elzarkaa,Waleed Shaalan,Doaa Elemam,Hassan Mansour,Mahmoud Melis,Eduard Malik,Amr A. Soliman 대한부인종양학회 2018 Journal of Gynecologic Oncology Vol.29 No.4
OBJECTIVE: A numerical score, the peritoneal cancer index (PCI), was developed to reflect the extent of tumor growth in gastric and colorectal cancers and to tailor treatment. This study aimed to examine the value of the PCI score in advanced epithelial ovarian cancer (EOC) regarding completeness of surgical cytoreduction and survival. METHODS: This was a prospective observational cohort study. Patients with primary serous EOC at International Federation of Gynecology and Obstetrics (FIGO) stages IIIB or higher were included. Patients with FIGO stage IVB as well as those assigned to receive neoadjuvant treatment were excluded from the study. The PCI was obtained and registered intraoperatively. RESULTS: In the study period we recruited 96 patients with serous EOC stage IIIB-IVA. A PCI score cut-off value of 13 was calculated using a receiver operator characteristic (ROC) curve, above which worse survival is expected (area under the curve [AUC]=0.641; 95% confidence interval [CI]=0.517-0.765; sensitivity and specificity 80.6%, 45.0%, respectively; p=0.050). A multivariate analysis determined that suboptimal surgical cytoreduction was the only independent predictive factor for recurrence (odds ratio [OR]=7.548; 95% CI=1.473-38.675; p=0.015). A multivariate analysis determined that only suboptimal surgical cytoreduction (hazard ratio [HR]=2.33; 95% CI=0.616-8.795; p=0.005), but not PCI score >13 (HR=1.289; 95% CI=0.329-5.046; p=0.716), was an independent predictive factor for death. CONCLUSION: We conclude from this study that the PCI score is a reliable tool helping to assess the extent of disease in advanced serous EOC patients and may help predicting complete surgical cytoreduction but cannot qualify as a predictor of survival.
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Numerical and experimental investigations on the hydrodynamic radial force of single-channel pumps
Linwei Tan,Wei-dong Shi,Desheng Zhang,Chuan Wang,Ling Zhou,Elemam Mahmoud 대한기계학회 2018 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.32 No.10
In order to clarify the generation mechanism and characteristics of hydrodynamic radial force in single-channel pumps, the transient flow in three single-channel pumps was analyzed by computational fluid dynamics (CFD). The three pumps had the identical impeller but with a spiral volute (model 1), a circular volute (model 2), and a torus (model 3). Experiments on pump performance were performed and high frequency pressure sensors were mounted in the spiral volute to measure pressure distribution in the volute of model 1. It indicates that the numerical results are approximately consistent with the experimental results. The radial force is mainly caused by the pressure acting on the blade. The impeller radial force in model 1 was the largest while the model 3 was the smallest, as it is not affected by rotor stator interaction, and rotor stator interaction plays a vital role in the shock load of pumps. The radial forces of different rotational speed were analyzed and indicated that Reynolds number has little influence on the radial force coefficient C F . The dominant frequency of the radial force on the impeller is the rotational frequency of impeller for all rotational speeds. Moreover, the amplitude of the radial force fluctuations increased with increasing flow rate in model 2, but the change was not obvious with the increasing of flow rate in model 3, while at lower flow rate the largest amplitude of the radial force fluctuations was presented in models 1.
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