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Dho, Yun-Sik,Kim, Yong Hwy,Se, Young-Bem,Han, Doo Hee,Kim, Jung Hee,Park, Chul-Kee,Wang, Kyu-Chang,Kim, Dong Gyu American Association of Neurological Surgeons 2018 Journal of Neurosurgery Vol.129 No.3
<B>OBJECTIVE</B><P>The endoscopic endonasal approach (EEA) is commonly used for the treatment of craniopharyngioma; therefore, it is essential to analyze outcomes in order to understand the benefits and drawbacks. The goal of this paper was to evaluate the clinical features and outcomes associated with this treatment approach.</P><B>METHODS</B><P>From July 2010 to March 2016, 82 adult craniopharyngioma patients underwent an EEA at the authors’ institution. Of these cases, intraoperative records and immediate postoperative MR images were available for 68 patients. The patients underwent systemized endocrinological evaluation. Eighteen of 68 patients who underwent EEA for recurrence or regrowth of residual lesions after previous surgical management were excluded in the analysis of the anatomical tumor classification. The authors retrospectively analyzed preoperative clinical features and previous anatomical classifications, focusing on the relationship of the pituitary stalk and tumor, to determine predictive factors for the clinical outcome, such as the extent of resection, visual function, endocrinological function, recurrence rate, and complications.</P><B>RESULTS</B><P>The mean tumor size was 2.5 cm (3.1 cm for primary tumors and 1.9 cm for recurrent lesions). Gross-total resection (GTR) was achieved in 62 (91.1%) patients (48 [96.0%] patients with primary tumors and 14 [77.8%] patients with recurrent tumors). The rate of GTR was higher in the primary group than in the group with recurrence (p = 0.038). The overall pre- and postoperative visual impairment scale (VIS) scores were 40.8 and 22.1, respectively (50.9 and 14.3 in the primary group and 30.7 and 29.9 in patients with recurrence, respectively). The improvement rate in VIS score was higher in the primary group than in the recurrent group (p = 0.001). Endocrinological function was improved in 4 patients (5.9%) and deteriorated in 32 of 68 patients (47.1%). Tumor invasion into the center of the pituitary stalk affected the postoperative outcomes most significantly. Cognitive dysfunction was observed in 22 patients before surgery and improved in 20 patients (90.9%) after surgery. Hydrocephalus was found in 7 patients and resolved after surgery in all cases. CSF leakage occurred in 2 (2.9%) of 68 patients and was repaired by revision surgery in both patients. Ten patients without CSF leakage also received antibiotics for the treatment of meningitis. The infection rate was higher in the recurrent group. Postoperative endocrinological evaluation showed no deficits in 12 patients and panhypopituitarism in 55 patients. The remaining patient had growth hormone deficiency. Forty-three patients had new-onset diabetes insipidus, and 1 patient had persistent diabetes insipidus after surgery. There were 2 (2.9%) cases of recurrence during the mean 30.7-month follow-up period; one patient underwent radiosurgery and the other underwent reoperation.</P><B>CONCLUSIONS</B><P>The EEA resulted in excellent surgical outcomes and acceptable morbidity rates, regardless of the anatomical location of the tumor. Invasion of the craniopharyngioma into the center of the pituitary stalk has strong predictive power for postoperative endocrinological outcome.</P>
Flotation Kinetics-Schuhmann's Modelling and Experimental Study
Dho, Hyon Seung 청주대학교 산업과학연구소 1997 産業科學硏究 Vol.15 No.2
Schuhmann의 속도 modelling을 인회석의 연속 부선 실험결과에 적용하였다. batch나 semi-batch 형태의 부선 실험과 달리 연속 부선 cell을 이용시 인회석의 부선 상태를 정량적으로 평가할 수 있었다. 실험결과 인회석의 부선에서 밝혀지지 않았던 규산나트륨의 역할은 특정 부선 속도와 인회석의 광물화 계수를 향상시키고 따라서 상대 부선 속도를 증가시킴을 정량적으로 평가할 수 있었다.
Investigation of the location of atypical teratoid/rhabdoid tumor.
Dho, Yun-Sik,Kim, Seung-Ki,Cheon, Jung-Eun,Park, Sung-Hye,Wang, Kyu-Chang,Lee, Ji Yeoun,Phi, Ji Hoon Springer Verlag 2015 Child's nervous system Vol.31 No.8
<P>The location of a brain tumor is a fundamental characteristic, because various brain tumors develop in relatively specific locations. An atypical teratoid/rhabdoid tumor (AT/RT) is a highly age-specific tumor that occurs in infants and young children. However, AT/RTs develop in a variety of locations in the brain. This study aimed at uncovering the tumor location pattern of AT/RTs to enhance diagnoses.</P>
Dho, Ho-Seog,Seo, Myung-Hwan,Kim, Rin-Ah,Kim, Tae-Man,Cho, Chun-Hyung Korean Radioactive Waste Society 2020 방사성폐기물학회지 Vol.18 No.4
Currently, radioactive waste for disposal has been restricted to low and intermediate level radioactive waste generated during operation of nuclear power plants, and these radioactive wastes were managed and disposed of the 200 L and 320 L of steel drums. However, it is expected that it will be difficult to manage a large amount of decommissioning waste of the Kori unit 1 with the existing drums and transportation containers. Accordingly, the KORAD is currently developing various and large-sized containers for packaging, transportation, and disposal of decommissioning waste. In this study, the radiation exposure doses of workers and the public were evaluated using RADTRAN computational analysis code in case of the domestic on-road transportation of new package and transportation containers under development. The results were compared with the domestic annual dose limit. In addition, the sensitivity of the expected exposure dose according to the change in the leakage rate of radionuclides in the waste packaging was evaluated. As a result of the evaluation, it was confirmed that the exposure dose under normal and accident condition was less than the domestic annual exposure dose limit. However, in the case of a number of loading and unloading operations, working systems should be prepared to reduce the exposure of workers.
External Field Dependence of $Fe^57$ NMR in Pure Iron
Dho, Joongheo,Kim, Mincheol,Lee, Soonchil,Lee, Wonjong,Kim, Yoonbae The Korean Magnetics Society 1996 Journal of Magnetics Vol.1 No.1
The NMR spin echo in pure iron was measured as a function of external magnetic field up to 10 kgauss at room temperature. We observed the signal coming from a single domain formed over 7.5 kgauss which has not been detected in previous works. The resonance frequency shift with external field confirmed that the hyperfine field in iron is -330.2 kgauss. From the comparison of the magnetization curve with the domain wall signal and the resonance frequency in external field, we showed that NMR could give the useful qualitative information on the magnetization process. The extent of the internal strain removed by annealing, which can be hardly seen in hysteresis curves, was clearly shown up in the NMR line-width.