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RISS 인기검색어
- 검색키워드
- 저자 : Deng Youwen (검색결과 3 건)
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Nonlinear Increase of Spatial Noise for Ultrashort Pulses with Different Temporal Widths
Lifu Zhang,Xiquan Fu,Jianqin Deng,Hua Yang,Youwen Wang,Shuangchun Wen,Huiwen Xu,Jinggui Zhang,Jin Zhang,Dianyuan Fan 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.2
In this paper, the dynamic evolution of the spatial noise modulation of ultrashort laser pulses in carbon disulfide (CS2) is investigated experimentally, and different temporal widths of the stretched pulse are analyzed for spatial noise gain. The spatial noise evolution (i.e., small-scale self-focusing) of ultrashort laser pulses with different temporal widths as a function of the length of the CS2 has been observed. If the spectral bandwidth is invariant, the experimental results show that a stretched pulse with a broader temporal width can postpone the small-scale self-focusing of spatial noise for longer medium length with constant input power or for greater input power with the same medium length. In this paper, the dynamic evolution of the spatial noise modulation of ultrashort laser pulses in carbon disulfide (CS2) is investigated experimentally, and different temporal widths of the stretched pulse are analyzed for spatial noise gain. The spatial noise evolution (i.e., small-scale self-focusing) of ultrashort laser pulses with different temporal widths as a function of the length of the CS2 has been observed. If the spectral bandwidth is invariant, the experimental results show that a stretched pulse with a broader temporal width can postpone the small-scale self-focusing of spatial noise for longer medium length with constant input power or for greater input power with the same medium length.
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LncRNA expression profile analysis of Mg2+-induced osteogenesis by RNA-seq and bioinformatics
Tang Wen,Liu Qing,Tan Wei,Sun Tianshi,Deng Youwen 한국유전학회 2021 Genes & Genomics Vol.43 No.11
Background In recent years, magnesium (Mg) has been extensively studied for manufacturing biodegradable orthopedic devices. Besides other advantages, researches have shown that magnesium-based implants can stimulate osteogenesis thus accelerating orthopedic trauma recovery, but its molecular mechanism is not fully understood. Meanwhile, long non-coding RNA (lncRNA) has been found to play vital role in regulating osteogenic diferentiation. Objective To explore the role of lncRNA in Mg2+ (magnesium ions)-induced osteogenesis. Methods The efect of Mg2+ on mBMSCs proliferation was detected by the CCK-8 assay. The optimum concentration of Mg2+ (7.5 mM) in promoting mBMSCs osteogenesis was determined by ALP staining and Alizarin red staining, western blot and RT-qPCR were performed to detect osteogenic markers expressions. The lncRNAs and mRNAs expression profles of mBMSCs were assessed by RNA-Seq and processed by bioinformatics analysis. The selected lncRNAs expression level was validated by RT-qPCR. Results The efect of Mg2+ in promoting osteogenesis was confrmed and the optimum concentration was determined as 7.5 mM. The lncRNAs and mRNAs diferentially expressed between 7.5 mM Mg2+-treated group and control group was detected and functional analysis revealed that their function were associated with osteogenesis. The ceRNA networks were constructed for H19 and Dubr that aberrantly expressed in two groups. The ceRNA networks of selected lncRNAs (H19 and Dubr) were constructed. Conclusions This study identifed H19 and Dubr as osteogenic associated lncRNAs involved in Mg2+-induced osteogenesis, and they might play their roles through lncRNA-miRNA–mRNA axis.
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Construction of magnetic nanochains to achieve magnetic energy coupling in scaffold
Cijun Shuai,Xuan Chen,Chongxian He,Guowen Qian,Yang Shuai,SHUPING PENG,Youwen Deng,Wenjing Yang 한국생체재료학회 2022 생체재료학회지 Vol.26 No.3
Background: Fe3O4 nanoparticles are highly desired for constructing endogenous magnetic microenvironment in scaffold to accelerate bone regeneration due to their superior magnetism. However, their random arrangement easily leads to mutual consumption of magnetic poles, thereby weakening the magnetic stimulation effect. Methods: In this study, magnetic nanochains are synthesized by magnetic-field-guided interface co-assembly of Fe3O4 nanoparticles. In detail, multiple Fe3O4 nanoparticles are aligned along the direction of magnetic force lines and are connected in series to form nanochain structures under an external magnetic field. Subsequently, the nanochain structures are covered and fixed by depositing a thin layer of silica (SiO2), and consequently forming linear magnetic nanochains (Fe3O4@SiO2). The Fe3O4@SiO2 nanochains are then incorporated into poly l-lactic acid (PLLA) scaffold prepared by selective laser sintering technology. Results: The results show that the Fe3O4@SiO2 nanochains with unique core–shell structure are successfully constructed. Meanwhile, the orderly assembly of nanoparticles in the Fe3O4@SiO2 nanochains enable to form magnetic energy coupling and obtain a highly magnetic micro-field. The in vitro tests indicate that the PLLA/Fe3O4@SiO2 scaffolds exhibit superior capacity in enhancing cell activity, improving osteogenesis-related gene expressions, and inducing cell mineralization compared with PLLA and PLLA/Fe3O4 scaffolds. Conclusion: In short, the Fe3O4@SiO2 nanochains endow scaffolds with good magnetism and cytocompatibility, which have great potential in accelerating bone repair
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