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      • KCI등재

        Application of Adaptive Neuro-Fuzzy Inference System for Evaluating Compressive Strength of Concrete

        Deepak Kumar Sinha,Rupali Satavalekar,Senthil Kasilingam 한국지능시스템학회 2021 INTERNATIONAL JOURNAL of FUZZY LOGIC and INTELLIGE Vol.21 No.2

        The objectives of this study are to develop a model for predicting the compressive strength of concrete using an adaptive neuro-fuzzy inference system (ANFIS) and validate the mix proportion using artificial neural networks (ANNs) and by experimentation. A model was developed, and the compressive strength was predicted using the ANFIS (with the subtractive clustering method of the fuzzy inference system) by MATLAB programming. In the present study, two ANFIS models were considered: ANFIS models-1 and -2. ANFIS model-1 was developed to predict the 3-day compressive strength, whereas ANFIS model-2 predicts the 28-day compressive strength by considering the 3-day compressive strength data obtained using ANFIS model-1. It was observed that the errors in the 3- and 28-day compressive strengths were 6.33%, and 17.07%, respectively. Furthermore, experiments were performed for selective mixes-M40, M50, and M60-to verify the compressive strength obtained using the ANFIS model. The model results were verified against the experimental ones based on the mixes selected from the model, and the results were found to agree with the predicted ones, with a maximum deviation of 18%. Furthermore, an ANN model was developed to predict the compressive strength to verify the accuracy of the ANFIS model. The results predicted by the ANFIS and the ANN were compared with the original results available in the literature. A significant deviation was found between the ANN model results and the original results, however, the ANN model results presented the same trend as the original results. It was concluded that the ANFIS model results were highly consistent with the original results.

      • KCI등재

        Original Articlet:Comparing the Efficacy of Latanoprost (0.005%), Bimatoprost (0.03%), Travoprost (0.004%), and Timolol (0.5%) in the Treatment of Primary Open Angle Glaucoma

        ( Deepak Mishra ),( Bibhuti Prassan Sinha ),( Mahendra Singh Kumar ) 대한안과학회 2014 Korean Journal of Ophthalmology Vol.28 No.5

        Purpose: To compare the efficacy and safety of latanoprost, bimatoprost, travoprost and timolol in reducing intraocular pressure (IOP) in patients with primary open angle glaucoma. Methods: This was a prospective study conducted at a tertiary-care centre. One hundred and forty patients with newly diagnosed primary open angle glaucoma were randomly assigned to treatment with latanoprost (0.005%), bimatoprost (0.03%), travoprost (0.004%) or timolol gel (0.5%); 35 patients were assigned to each group. All patients were followed for 2, 6, and 12 weeks. The main outcome measure studied was the change in IOP at week 12 from the baseline values. Safety measures included recording of adverse events. Results: The mean IOP reduction from baseline at week 12 was significantly more with bimatoprost (8.8 mmHg, 35.9%) than with latanoprost (7.3 mmHg, 29.9%), travoprost (7.6 mmHg, 30.8%) or timolol (6.7 mmHg, 26.6%) (ANOVA and Student`s t-tests, p < 0.001). Among the prostaglandins studied, bimatoprost produced a maximum reduction in IOP (-2.71; 95% confidence interval [CI], -2.25 to -3.18) followed by travoprost (-1.27; 95% CI, -0.81 to -1.27) and latanoprost (-1.25; 95% CI, -0.79 to -1.71); these values were significant when compared to timolol at week 12 (Bonferroni test, p < 0.001). Latanoprost and travoprost were comparable in their ability to reduce IOP at each patient visit. Ocular adverse-events were found in almost equal proportion in patients treated with bimatoprost (41.3%) and travoprost (41.9%), with a higher incidence of conjunctival hyperemia (24.1%) seen in the bimatoprost group. Timolol produced a significant drop in heart rate (p < 0.001) at week 12 when compared to the baseline measurements. Conclusions: Bimatoprost showed greater efficacy when compared to the other prostaglandins, and timolol was the most efficacious at lowering the IOP. Conjunctional hyperemia was mainly seen with bimatoprost. However, the drug was tolerated well and found to be safe.

      • KCI등재

        Leiomyosarcoma, a Nonurothelial Bladder Tumor: A Rare Entity With Therapeutic Diversity

        Dheeraj Kumar Gupta,Vishwajeet Singh,Rahul Janak Sinha,Vijay Kumar,Deepak Sharanappa Nagathan,Satya Narayan Sankhwar 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.6

        A 22-year-old young woman presented with dysuria and lower urinary tract symptoms that had persisted for 6 months. She was diagnosed with a tumor near the bladder neck. Transurethral resection was done under anaesthesia. The histopathological examination with immunohistochemical staining showed the tumor to be a low-grade leiomyosarcoma. Adjuvant chemoradiation was given, and the patient has been doing well for 12 months of follow-up. Nonurothelial tumors of the bladder are rare and consensus is lacking regarding their definitive treatment. Furthermore, little is known about the natural history and prognosis of this type of bladder sarcoma. We present a minimally invasive treatment for this relatively rare tumor in which bladder preservation was achieved with no evidence of local or distant recurrences during the follow-up to date.

      • The Single Cigarette Economy in India - a Back of the Envelope Survey to Estimate its Magnitude

        Lal, Pranay,Kumar, Ravinder,Ray, Shreelekha,Sharma, Narinder,Bhattarcharya, Bhaktimay,Mishra, Deepak,Sinha, Mukesh K.,Christian, Anant,Rathinam, Arul,Singh, Gurbinder Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.13

        Background: Sale of single cigarettes is an important factor for early experimentation, initiation and persistence of tobacco use and a vital factor in the smoking epidemic in India as it is globally. Single cigarettes also promote the sale of illicit cigarettes and neutralises the effect of pack warnings and effective taxation, making tobacco more accessible and affordable to minors. This is the first study to our knowledge which estimates the size of the single stick market in India. Materials and Methods: In February 2014, a 10 jurisdiction survey was conducted across India to estimate the sale of cigarettes in packs and sticks, by brands and price over a full business day. Results: We estimate that nearly 75% of all cigarettes are sold as single sticks annually, which translates to nearly half a billion US dollars or 30 percent of the India's excise revenues from all cigarettes. This is the price which the consumers pay but is not captured through tax and therefore pervades into an informal economy. Conclusions: Tracking the retail price of single cigarettes is an efficient way to determine the willingness to pay by cigarette smokers and is a possible method to determine the tax rates in the absence of any other rationale.

      • KCI등재

        Tricholithobezoar: An Unusual Late Complication of Neourethral Reconstruction in Aphallia

        Vishwajeet Singh,Deepak Sharanappa Nagathan,Rahul Janak Sinha,Dheeraj Kumar Gupta 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.5

        An 18-year-old man born with aphallia had undergone phallic reconstruction in childhood followed by total urethral reconstruction with a buccal mucosal graft and groin-based pedicle (Singapore) flap urethroplasty at 13 years of age. The patient presented with obstructive voiding symptoms lasting 6 months followed by acute urinary retention. The results of a voiding cystourethrogram showed a filling defect in the distal urethra that had been reconstructed by use of the skin flap. On urethroscopy, a 3 cm×2cm sized tricholithobezoar was seen in the distal urethra. Pneumatic lithotripsy followed by bulbar urethrolithotomy was performed in the same operation to extract the bezoar. The remaining hairs were mechanically epilated. The patient has been doing well for 6 months of follow-up.

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