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        Small Bowel Stent-in-Stent Placement for Malignant Small Bowel Obstruction Using a Balloon-Assisted Overtube Technique

        Daniel Popa,Jayapal Ramesh,Shajan Peter,C. Mel Wilcox,Klaus Mönkemüller 대한소화기내시경학회 2014 Clinical Endoscopy Vol.47 No.1

        Self-expanding metal stents are a useful therapy to palliate malignant and benign luminal gastrointestinal obstruction. Self-expanding metal stents has been widely reported for colonic, esophageal, and gastric obstruction. However, endoscopic delivery and placement to the small bowel is more challenging and difficult. This case illustrates the usefulness and technical advantages of the balloon-overtube and enteroscopy technique for the palliative treatment of neoplastic stenosis affecting the small intestine.

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        Photoluminescent Red, Green and Blue Monoliths of New Eu(III), Tb(III) and Y(III) Complexes Embedded in Silica Matrix

        Corneliu S. Stan,Marcel Popa,Daniel Sutiman,Petronela Horlescu 대한금속·재료학회 2014 ELECTRONIC MATERIALS LETTERS Vol.10 No.4

        Large transparent photoluminescent monoliths were prepared by embedding newly synthesized Eu(III), Tb(III) and Y(III) complexes with 2-(1H-1,2,4-Triazol-3-yl)pyridine ligand in silica matrices through a modified sol-gel process. The remarkable luminescent properties of the free complexes were preserved in silica matrix, resulting in red, green and blue monoliths with a shape that may be tailored during the gelation process according to specific applications. Prior to embedment, the complexes prepared at 1/3 metal to ligand ratio were investigated through elemental analysis, thermal analysis, FT-IR, mass and fluorescence spectroscopy while the obtained silica monoliths were supplementary investigated through SEM and fluorescence spectroscopy. The emission peaks are located at 612 nm for the monolithic silica embedded Eu(III) complex, at 542 nm for the monolithic silica embedded Tb(III) complex and at 482 nm respectively for the silica monolith containing the Y(III) complex. Their excellent photoluminescent properties may recommend them as photonic conversion materials in various optoelectronic applications.

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        Breaking Barriers in Functional Dyspepsia: A Systematic Review and Meta-analysis on Duodenal Tight Junction Protein Expression

        Radu A Farcas,Malaz Almasri,Simona Grad,Stefan-Lucian Popa,Daniel C Leucuta,Abdulrahman Ismaiel,Dan L Dumitrascu 대한소화기 기능성질환∙운동학회 2024 Journal of Neurogastroenterology and Motility (JNM Vol.30 No.3

        Background/AimsDisruptions in tight junction (TJ) protein expression leading to duodenal epithelial barrier impairment may contribute to increased intestinal permeability, potentially playing a role in functional dyspepsia (FD) pathophysiology. Currently published studies evaluated the role of several TJ proteins in FD patients with inconsistent results. Therefore, we conducted this systematic review and metaanalysis to evaluate the duodenal mucosal expression of several TJ proteins in FD. MethodsWe performed a systematic electronic search on PubMed, EMBASE, and Scopus using predefined keywords. Diagnosis of FD by Rome III or Rome IV criteria was considered acceptable. Full articles satisfying our inclusion and exclusion criteria were included. The principal summary outcome was the mean difference of several TJ proteins in FD patients and control subjects. ResultsA total of 8 and 5 studies were included in our qualitative and quantitative synthesis, respectively, with a total population of 666 participants, out of which 420 were FD patients. No significant differences were observed between FD patients and controls in the expression of claudin-1 (–0.102 [95% CI, –0.303, 0.099]), claudin-2 (0.161 [95% CI, –0.134, 0.456)], claudin-3 (0.278 [95% CI, –0.280, 0.837]), claudin-4 (0.045 [95% CI, –0.264, 0.354]), ZO-1 (–0.221 [95% CI, –0.683, 0.241]), ZO-2 (–0.070 [95% CI, –0.147, 0.007]), ZO-3 (–0.129 [95% CI, –0.376, 0.118]), β-catenin (–0.135 [95% CI, –0.484, 0.214]), E-cadherin (–0.083 [95% CI, –0.229, 0.063]), and occludin (–0.158 [95% CI, –0.409, 0.093]). ConclusionsThe expressions of all evaluated proteins including claudin-1, claudin-2, claudin-3, claudin-4, ZO-1, ZO-2, ZO-3, β-catenin, E-cadherin, and occludin did not significantly differ between FD patients and controls. However, due to the limited number of included studies, results should be interpreted with caution.

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