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Conge Tan,Weijun Ding,Wenzhe Feng,Jianguo Wang,Miqu Wang 사단법인약침학회 2010 Journal of Acupuncture & Meridian Studies Vol.3 No.3
The warm needling technique used in traditional Chinese medicine has been shown to be effective in the treatment and prevention of knee osteoarthritis (OA), but the biological mechanisms behind this action have not been well explored. This study investigated the molecular mechanisms behind warm needling using cDNA microarray technology, thus providing further scientific evidence for its efficacy. Ten patients with knee OA of deficiency-cold syndrome were selected for 2 weeks of warm needling treatment. This treatment involved stimulating the selected acupoints using needles with a burning moxa stick on their handle for 40 minutes per session. Pain intensity and accumulated clinical scores of deficiency-cold syndrome were assessed pretreatment and posttreatment using a 40-factor questionnaire of OA with deficiency-cold syndrome. Four patients with the best therapeutic efficacy were selected for cDNA microarray testing. Among the four patients, 41, 246,57 and 70 differentially expressed genes were obtained, with more than 50% of these differentially expressed genes functionally linked to primary, cellular and energy metabolism pathways. This work demonstrates that the molecular mechanism behind warm needling treatment may be associated with the regulation of metabolism-related genes and pathways.
Investigation of Cavitation Models for Steady and Unsteady Cavitating Flow Simulation
Tan Dung Tran,Bernd Nennemann,Thi Cong Vu,François Guibault 한국유체기계학회 2015 International journal of fluid machinery and syste Vol.8 No.4
The objective of this paper is to evaluate the applicability of mass transfer cavitation models and determine appropriate numerical parameters for cavitating flow simulations. CFD simulations were performed for a NACA66 hydrofoil at cavitation numbers of 1.49 and 1.00, corresponding to steady sheet and unsteady sheet/cloud cavitating regimes using the Kubota and Merkle cavitation models. The Merkle model was implemented into CFX by User Fortran code. The Merkle cavitation model is found to give some improvements for cavitating flow simulation results for these cases. Turbulence modeling is also found to have an important contribution to the prediction quality of the simulations. The relationship between the turbulence viscosity modification, in order to take into account the local compressibility at the vapor/liquid interfaces, and the predicted numerical results is clarified. The limitations of current cavitating flow simulation techniques are discussed throughout the paper.
Investigation of Cavitation Models for Steady and Unsteady Cavitating Flow Simulation
Tran, Tan Dung,Nennemann, Bernd,Vu, Thi Cong,Guibault, Francois Korean Society for Fluid machinery 2015 International journal of fluid machinery and syste Vol.8 No.4
The objective of this paper is to evaluate the applicability of mass transfer cavitation models and determine appropriate numerical parameters for cavitating flow simulations. CFD simulations were performed for a NACA66 hydrofoil at cavitation numbers of 1.49 and 1.00, corresponding to steady sheet and unsteady sheet/cloud cavitating regimes using the Kubota and Merkle cavitation models. The Merkle model was implemented into CFX by User Fortran code. The Merkle cavitation model is found to give some improvements for cavitating flow simulation results for these cases. Turbulence modeling is also found to have an important contribution to the prediction quality of the simulations. The relationship between the turbulence viscosity modification, in order to take into account the local compressibility at the vapor/liquid interfaces, and the predicted numerical results is clarified. The limitations of current cavitating flow simulation techniques are discussed throughout the paper.
Liu Cong,Zhang Bin,Wei Junxia,Tan Shuang 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.2
Neutron transport calculations are extremely challenging due to the high computational cost of large and complex problems. A multilevel octree grid algorithm (MLTG) of discrete ordinates method was developed to improve the modeling accuracy and simulation efficiency on 3-D Cartesian grids. The Balakovo-3 VVER-1000 neutron dosimetry benchmark is calculated to verify and validate this numerical technique. A simplified S2 synthetic acceleration is used in the MLTG calculation method to improve the convergence of the source iterations. For the triangularly arranged fuel pins, we adopt a source projection algorithm to generate pin-by-pin source distributions of hexagonal assemblies. MLTG provides accurate geometric modeling and flexible fixed source description at a lower cost than traditional Cartesian grids. The total number of meshes is reduced to 1.9 million from the initial 9.5 million for the Balakovo-3 model. The numerical comparisons show that the MLTG results are in satisfactory agreement with the conventional SN method and experimental data, within the root-mean-square errors of about 4% and 10%, respectively. Compared to uniform fine meshing, approximately 70% of the computational cost can be saved using the MLTG algorithm for the Balakovo-3 computational model.
Huynh Tan Nhut,Nguyen Tri Quang Hung,Tran Cong Sac,Nguyen Huynh Khanh Bang,Tran Quang Tri,Nguyen Trung Hiep,Nguyen Minh Ky 대한환경공학회 2020 Environmental Engineering Research Vol.25 No.5
This study evaluates the efficiency of domestic wastewater treatment via Sponge-Based Moving Bed Biofilm Reactor (S-MBBR). The laboratory-based treatment plan uses polyurethane sponge with a specific surface area was 260 ㎡/㎥ as a carrier. The treatment plan operated under four different organic load rate: OLR1 = 0.4 ㎏ BOD/㎥.day; OLR2 = 0.6 ㎏ BOD/㎥.day; OLR3 = 0.8 ㎏ BOD/㎥.day; and OLR4 = 1.0 ㎏ BOD/㎥.day. During 80 d of the experiment, the highest treatment efficiency was at the organic load rate of 0.4 ㎏ BOD/㎥.day, with COD, SS, TN and TP were found to be 85.0 ± 12.9%, 85.7 ± 5.3%, 68.9 ± 1.7%, and 40.3 ± 0.2%, respectively. In which, the influent SS concentration were from 117.3 to 126.0 ㎎/L, the effluent concentration were in ranged 18.0 to 34.22 ㎎/L, respectively. The values of influent and effluent COD were 298.8 ± 12.88 and 44.8 ± 3.78 ㎎/L in turn. The OLR1 influent TN, TP concentrations were respectively 47.9 ± 2.11 and 3.6 ± 0.15 ㎎/L; the effluent TN, TP concentration were 14.9 ± 0.18 and 2.2 ± 0.06 ㎎/L, respectively. The study suggests that the effluent is within the allowable limits of National technical regulation on domestic wastewater (Column B1), indicating the applicability of S-MBBR for the domestic wastewater treatment plant.