Constrained High Accuracy Stereo Reconstruction Method for Surgical Instruments Positioning

( Chenhao Wang ),( Yi Shen ),( Wenbin Zhang ),( Yuncai Liu ) 한국인터넷정보학회 2012 KSII Transactions on Internet and Information Syst Vol.6 No.10

In this paper, a high accuracy stereo reconstruction method for surgery instruments positioning is proposed. Usually, the problem of surgical instruments reconstruction is considered as a basic task in computer vision to estimate the 3-D position of each marker on a surgery instrument from three pairs of image points. However, the existing methods considered the 3-D reconstruction of the points separately thus ignore the structure information. Meanwhile, the errors from light variation, imaging noise and quantization still affect the reconstruction accuracy. This paper proposes a method which takes the structure information of surgical instruments as constraints, and reconstructs the whole markers on one surgical instrument together. Firstly, we calibrate the instruments before navigation to get the structure parameters. The structure parameters consist of markers` number, distances between each markers and a linearity sign of each instrument. Then, the structure constraints are added to stereo reconstruction. Finally, weighted filter is used to reduce the jitter. Experiments conducted on surgery navigation system showed that our method not only improve accuracy effectively but also reduce the jitter of surgical instrument greatly.

Sulforaphane Ameliorates Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7

Lili Kong,Hongyue Wang,Chenhao Li,Huiyan Cheng,Yan Cui,Li Liu,Ying Zhao 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.6

Background: The dietary agent sulforaphane (SFN) has been reported to reduce diabetes-induced renal fibrosis, as well as inhibit histone deacetylase (HDAC) activity. Bone morphologic protein 7 (BMP-7) has been shown to reduce renal fibrosis induced by transforming growth factor-beta1. The aim of this study was to investigate the epigenetic effect of SFN on BMP-7 expression in diabetes-induced renal fibrosis.Methods: Streptozotocin (STZ)-induced diabetic mice and age-matched controls were subcutaneously injected with SFN or vehicle for 4 months to measure the in vivo effects of SFN on the kidneys. The human renal proximal tubular (HK11) cell line was used to mimic diabetic conditions in vitro. HK11 cells were transfected to over-express HDAC2 and treated with high glucose/palmitate (HG/Pal) to explore the epigenetic modulation of BMP-7 in SFN-mediated protection against HG/Pal-induced renal fibrosis.Results: SFN significantly attenuated diabetes-induced renal fibrosis in vivo. Among all of the HDACs we detected, HDAC2 activity was markedly elevated in the STZ-induced diabetic kidneys and HG/Pal-treated HK11 cells. SFN inhibited the diabetes-induced increase in HDAC2 activity which was associated with histone acetylation and transcriptional activation of the BMP-7 promoter. HDAC2 over-expression reduced BMP-7 expression and abolished the SFN-mediated protection against HG/Pal-induced fibrosis in vitro.Conclusion: Our study demonstrates that the HDAC inhibitor SFN protects against diabetes-induced renal fibrosis through epigenetic up-regulation of BMP-7.

A Novel Zero-Crossing Compensation Scheme for Fixed Off-Time Controlled High Power Factor AC-DC LED Drivers

Chang, Changyuan,Sun, Hailong,Zhu, Wenwen,Chen, Yao,Wang, Chenhao The Korean Institute of Power Electronics 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.5

A fixed off-time controlled high power factor ac-dc LED driver is proposed in this paper, which employs a novel zero-crossing-compensation (ZCC) circuit based on a fixed off-time controlled scheme. Due to the parasitic parameters of the system, the practical waveforms have a dead region. By detecting the zero-crossing boundary, the proposed ZCC circuit compensates the control signal VCOMP within the dead region, and is invalid above this region. With further optimization of the parameters KR and Kτ of the ZCC circuit, the dead zone can be eliminated and lower THD is achieved. Finally, the chip is implemented in HHNEC 0.5μm 5V/40V HVCMOS process, and a prototype circuit, delivering 7~12W of power to several 3-W LED loads, is tested under AC input voltage ranging from 85V to 265V. The test results indicate that the average total harmonic distortion (THD) of the entire system is approximately 10%, with a minimum of 5.5%, and that the power factor is above 0.955, with a maximum of 0.999.

A Novel Zero-Crossing Compensation Scheme for Fixed Off-Time Controlled High Power Factor AC-DC LED Drivers

Changyuan Chang,Hailong Sun,Wenwen Zhu,Yao Chen,Chenhao Wang 전력전자학회 2016 JOURNAL OF POWER ELECTRONICS Vol.16 No.5

A fixed off-time controlled high power factor ac-dc LED driver is proposed in this paper, which employs a novel zero-crossing-compensation (ZCC) circuit based on a fixed off-time controlled scheme. Due to the parasitic parameters of the system, the practical waveforms have a dead region. By detecting the zero-crossing boundary, the proposed ZCC circuit compensates the control signal VCOMP within the dead region, and is invalid above this region. With further optimization of the parameters KR and Kτ of the ZCC circuit, the dead zone can be eliminated and lower THD is achieved. Finally, the chip is implemented in HHNEC 0.5㎛ 5V/40V HVCMOS process, and a prototype circuit, delivering 7~12W of power to several 3-W LED loads, is tested under AC input voltage ranging from 85V to 265V. The test results indicate that the average total harmonic distortion (THD) of the entire system is approximately 10%, with a minimum of 5.5%, and that the power factor is above 0.955, with a maximum of 0.999.

Effects of soft pellet creep feed on pre-weaning and post-weaning performance and intestinal development in piglets

Chen Hao,Wang Chunwei,Wang You,Chen Yilin,Wan Meng,Zhu Jiadong,Zhu Aixia 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.4

Objective: This study aimed to determine the effects of soft pellet creep feed (SPCF) on growth performance and intestinal development in piglets. Methods: A total of 18 sows and their litters of crossbred piglets (14±2 days, 3.73±0.72 kg) were assigned to one of three dietary groups receiving i) powder creep feed (PCF), ii) hard pellet creep feed (HPCF) or iii) SPCF during the pre-weaning period. After weaning, piglets were selected for continuous evaluation of the three diets on growth performance and intestinal health. Results: In the pre-weaning period, the average daily feed intake and average daily dry matter intake were significantly higher in the SPCF group than the HPCF group (p<0.05). In the post-weaning and entire experimental period, the different diets had no significant effect on growth performance. At 10 d after weaning, the serum glucose concentration was lower in the SPCF group (p<0.05) than the other groups; a higher (p<0.05) villus height and lower (p<0.05) crypt depth in the jejunum were also observed in the SPCF group than the other groups; Meanwhile, in the duodenum and jejunum, the SPCF group had a higher (p<0.05) villus height to crypt depth ratio than the other groups; Furthermore, the higher (p<0.05) threshold cycle values of lactic acid bacteria and lower (p<0.05) threshold cycle values of Clostridium, Enterobacter and Escherichia coli were also observed in the SPCF group, and the sucrase and maltase activity was higher (p<0.05) in the SPCF group than the other groups in duodenum and ileum. Conclusion: The SPCF improved pre-weaning feed intake and decreased the negative effects of weaning stress in the intestine in piglets. Objective: This study aimed to determine the effects of soft pellet creep feed (SPCF) on growth performance and intestinal development in piglets.Methods: A total of 18 sows and their litters of crossbred piglets (14±2 days, 3.73±0.72 kg) were assigned to one of three dietary groups receiving i) powder creep feed (PCF), ii) hard pellet creep feed (HPCF) or iii) SPCF during the pre-weaning period. After weaning, piglets were selected for continuous evaluation of the three diets on growth performance and intestinal health.Results: In the pre-weaning period, the average daily feed intake and average daily dry matter intake were significantly higher in the SPCF group than the HPCF group (p<0.05). In the post-weaning and entire experimental period, the different diets had no significant effect on growth performance. At 10 d after weaning, the serum glucose concentration was lower in the SPCF group (p<0.05) than the other groups; a higher (p<0.05) villus height and lower (p<0.05) crypt depth in the jejunum were also observed in the SPCF group than the other groups; Meanwhile, in the duodenum and jejunum, the SPCF group had a higher (p<0.05) villus height to crypt depth ratio than the other groups; Furthermore, the higher (p<0.05) threshold cycle values of lactic acid bacteria and lower (p<0.05) threshold cycle values of <i>Clostridium, Enterobacter and Escherichia coli</i> were also observed in the SPCF group, and the sucrase and maltase activity was higher (p<0.05) in the SPCF group than the other groups in duodenum and ileum.Conclusion: The SPCF improved pre-weaning feed intake and decreased the negative effects of weaning stress in the intestine in piglets.