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        Optimizing Energy-Latency Tradeoff for Computation Offloading in SDIN-Enabled MEC-based IIoT

        Xinchang Zhang,Changsen Xia,Tinghuai Ma,Lejun Zhang,Zilong Jin 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.12

        With the aim of tackling the contradiction between computation intensive industrial applications and resource-weak Edge Devices (EDs) in Industrial Internet of Things (IIoT), a novel computation task offloading scheme in SDIN-enabled MEC based IIoT is proposed in this paper. With the aim of reducing the task accomplished latency and energy consumption of EDs, a joint optimization method is proposed for optimizing the local CPU-cycle frequency, offloading decision, and wireless and computation resources allocation jointly. Based on the optimization, the task offloading problem is formulated into a Mixed Integer Nonlinear Programming (MINLP) problem which is a large-scale NP-hard problem. In order to solve this problem in an accessible time complexity, a sub-optimal algorithm GPCOA, which is based on hybrid evolutionary computation, is proposed. Outcomes of emulation revel that the proposed method outperforms other baseline methods, and the optimization result shows that the latency-related weight is efficient for reducing the task execution delay and improving the energy efficiency.

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        β-1,3-Glucan/CR3/SYK pathway-dependent LC3B-II accumulation enhanced the fungicidal activity in human neutrophils

        Ding Li,Changsen Bai,Qing Zhang,Zheng Li,Di Shao,Xichuan Li 한국미생물학회 2019 The journal of microbiology Vol.57 No.4

        Since molecular genotyping has been established for the Candida species, studies have found that a single Candida strain (endemic strain) can persist over a long period of time and results in the spread of nosocomial invasive candidiasis without general characteristics of horizontal transmissions. Our previous study also found the existence of endemic strains in a cancer center in Tianjin, China. In the current study, we performed further investigation on endemic and non-endemic Candida albicans strains, with the aim of explaining the higher morbidity of endemic strains. In an in vivo experiment, mice infected with endemic strains showed significantly shorter survival time and higher kidney fungal burdens compared to mice infected with non-endemic strains. In an in vitro experiment, the killing percentage of neutrophils to endemic strains was significantly lower than that to non-endemic strains, which is positively linked to the ratio of LC3B-II/I in neutrophils. An immunofluorescence assay showed more β-1,3-glucan exposure on the cell walls of nonendemic strains compared to endemic strains. After blocking the β-glucan receptor (CR3) or inhibiting downstream kinase (SYK) in neutrophils, the killing percent to C. albicans (regardless of endemic and non-endemic strains) and the ratio of LC3B-II/I of neutrophils were significantly decreased. These data suggested that the killing capability of neutrophils to C. albicans was monitored by β-1,3-glucan via CR3/SYK pathway-dependent LC3B-II accumulation and provided an explanation for the variable killing capability of neutrophils to different strains of C. albicans, which would be beneficial in improving infection control and therapeutic strategies for invasive candidiasis.

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        Transition metal modified manganese-based catalysts for soot oxidation promoted by noncompetitive adsorption of oxygen: Experiments and DFT calculations

        Congcong Li,Ruiqi Li,Yuhang Wang,Runhan Niu,Qilong Guo,Changsen Zhang 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

        A series of manganese-based oxide catalysts were synthesized by the hydrothermal method. By adjustingthe doping amounts of W and Cu in the system to study the catalytic performance of transition metaldopedmanganese oxides on soot combustion. They were deeply studied through various characterizationsand theoretical calculations. The results show that Wand Cu doping modifications can significantlyimprove the activity of manganese-based oxides in soot oxidation. W-Cu0.1/MnOx prepared by comodificationofWand Cu at 395 C can convert 90% of soot into CO2. The multiple characterization resultsshow that by adjusting the doping amount of copper and tungsten, the nano-flower-like morphology canbe obtained and the crystal plane can be reconstructed, which is helpful to increase the specific surfacearea, Mn3+ content, and oxygen vacancy content. The theoretical calculation results show that the oxygenvacancy on the surface of the catalyst shows the ability to activate O2 and H2O, and they show noncompetitiveadsorption. In addition, W-Cu0.1/MnOx has a good application prospect in the catalytic oxidationof soot because of its excellent catalytic stability. This work provides a reference for the designand preparation of non-noble metal-based catalysts for the elimination of soot particles from dieselengine exhaust.

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