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Ç;ağrıTürköz;Burcu BaloşTuncer;Mehmet Ç;ağrıUlusoy;Cumhur Tuncer 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.4
본 연구의 목적은 서로 다른 종류의 접착시스템과 법랑질보호제 등이 설측 브라켓의 인장강도에 영향을 미치는지 알아보는데 있다. 75개의 발치된 하악 전치를 5개의 그룹으로 임의로 나눈 후 설측 브라켓을 부착하였다. Group 1은 Transbond XT를, Group 2는 Transbond XT와 함께 불소 유리레진(Ortho-coat)을 Group 3는 Transbond XT와 Chlorohexidine varnish (Cervitec Plus)를 Group 4는 광중합 접착제(Aegis Ortho)를 Group 5는 antimicrobial self-etching primer(Clearfil Protect Bond)을 사용하였다. 불소유리 레진이나 Chlorohexidine varnish의 사용유무는 접착력에 영향을 미치지 못하였다. Group 5이 다른 그룹에 비해 접착력과 접착제 잔류지수(adhesive remnant index, ARI)가 통계적으로 유의하게 높았다 (p < 0.001). 법랑질 보호제 적용 시 설측 브라켓의 접착력에 부정적인 영향을 미치지 못하였다. 이상의 결과로 이번에 사용한 제품들은 설측 교정치료 기간 동안 환자의 구강위생을 개선시킬 수 있어 환자와 술자에게 도움을 줄 수 있을 것이다. 그러나 에나멜 층이 얇은 경우 Clearfil Protect Bond의 과도한 접착강도에 대해 고려해야 할 것이다. Objective: The aim of this study was to determine whether different types of adhesive systems and enamel-protective agents will affect the tensile bond strength of lingual brackets. Methods: A total of 75 extracted mandibular incisors were randomly divided into 5 groups and lingual brackets were bonded. Group 1 specimens received Transbond XT (3M Unitek, Monrovia, CA, USA), Group 2 required the application of a fluoride-releasing resin (Ortho-coat, Pulpdent, Watertown, MA, USA) with Transbond XT, Group 3 specimens received a chlorhexidine varnish (Cervitec Plus, Ivoclar Vivadent, Schaan, Lichtenstein) with Transbond XT. In Group 4, a light-cured orthodontic adhesive (Aegis Ortho, Bosworth, Skokie, USA) was applied and in Group 5, an antimicrobial self-etching primer (Clearfil Protect Bond, Kuraray, Osaka, Japan) was used. Results: There were no significant differences in bond strength whether fluoride-releasing resin or chlorhexidine varnish were used or not. Group 5 had significantly higher bond strength and adhesive remnant index (ARI) values than other groups (p < 0.001). The application of enamel-protective products did not have an adverse affect on the bond strength of lingual brackets. Conclusions: These products might provide benefits both for the patient and the clinician, by supporting the oral hygiene during lingual orthodontic treatment. The higher ARI score may be beneficial for Clearfil Protect Bond but its excessive bond strength should be considered in clinical practice, especially where the enamel is thin.
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Hasan Herken,Mehmet Emin Erdal,Ayse Nur Inci Kenar,Gonca Ayse Unal,Burcu Ç,akaloz,Mustafa Ertan Ay,Erinç,Yucel,Tuba Edgunlu,Cem Sengul 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.4
Objective-The synaptosomal-associated protein of 25 kDa (SNAP-25) gene is a presynaptic plasma membrane protein and an integral component of the vesicle docking and fusion machinery mediating secretion of neurotransmitters. Previously, several studies reported association between SNAP-25 and attention deficit hyperactivity disorder (ADHD). We investigated whether these SNAP-25 polymorphisms (MnlI T/G and DdelI T/C) were also associated with ADHD in the Turkish population. Methods-Our study comprised unrelated 139 subjects who met DSM-IV criteria for ADHD and 73 controls and all were of Turkish origin. Genetic analyses were performed and patients were evaluated with Wender-Utah Rating Scale and Adult ADD/ADHD DSM IV-Based Diagnostic Screening and Rating Scale. Results-SNAP-25 DdelI polymorphism was not associated with ADHD but there was a statistically significant difference between ADHD patients and controls for SNAP-25 MnlI polymorphism. For SNAP-25 MnlI polymorphism patients with G/G genotype of the SNAP-25 gene MnlI polymorphism had higher Wender-Utah scores and higher scores in the 1st and 3rd parts of adult ADD/ADHD Scale. Conclusion-We detected a significant association of the MnlI polymorphism in our ADHD sample which was similar to previous findings. Our study also revealed that SNAP-25 MnlI polymorphism was also associated with symptom severity of ADHD. This study is also, the first report on the association of SNAP-25 with ADHD in the Turkish population.
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