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RISS 인기검색어
- 검색키워드
- 저자 : Buqing Chen (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
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Off-Label Application of Pipeline Embolization Device for Intracranial Aneurysms
Liang Buqing,Lesley Walter S.,Robinson Timothy M.,Chen Wencong,Benardete Ethan A.,Huang Jason H. 대한신경중재치료의학회 2019 Neurointervention Vol.14 No.2
Purpose: The Pipeline embolization device (PED) is approved in the USA for treating giant and large aneurysms arising from the petrous to superior hypophyseal segments of the internal carotid artery in patients older than 21 years of age. This study investigates off-label PED results in a large cohort. Materials and Methods: Retrospective, single-center review of all patients who had off-label PED surgery. Results: Sixty-two aneurysms (48 patients) underwent off-label PED treatment from 2012–2017. There were 44 females and four males (age 21 to 75 years; mean/median, 54.3/55.0 years). The most common presenting symptom was headache (47/62, 75.8%). All aneurysms were in the anterior circulation. Aneurysm size ranged from 1.4 to 25.0 mm (mean/median, 7.6/6.9 mm). Fifty-two aneurysms had post-operative imaging with total/near-complete occlusion of 84.6% (44/52). Aneurysm-based operative near-term complication rate was 9.7% while there were no permanent complications. For aneurysms and headache, 86.7% improved/resolved after embo-surgery, and were four times more likely to have a better clinical outcome (resolved or improved symptoms) after surgery (odds ratio [OR], 4.333; P=0.0325). Left-sided aneurysms had a higher occlusion rate (OR, 20; P=0.0073). Hypertension (OR, 4.2; P=0.0332) and smoking (OR, 7; P=0.0155) were more prone towards aneurysm occlusion. Patients without a family history were 14 times more likely to have favorable imaging outcome (P=0.0405). There is no difference of occlusion rates between untreated and previously treated aneurysms (P=0.6894). Overall, occlusion rate decreased by 14% with an increase of aneurysm size by 1 mm (P=0.0283). Conclusion: For anterior circulation aneurysms, the off-label application of PED is as effective and safe as reported for on-label intracranial aneurysms.
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Dynamic behavior of SRC columns with built-in cross-shaped steels subjected to lateral impact
Yanhua Liu,Lei Zeng,Changjun Liu,Jinxu Mo,Buqing Chen 국제구조공학회 2020 Structural Engineering and Mechanics, An Int'l Jou Vol.76 No.4
This paper presents an investigation on the dynamic behavior of SRC columns with built-in cross-shaped steels under impact load. Seven 1/2 scaled SRC specimens were subjected to low-speed impact by a gravity drop hammer test system. Three main parameters, including the lateral impact height, the axial compression ratios and the stirrup spacing, were considered in the response analysis of the specimens. The failure mode, deformation, the absorbed energy of columns, as well as impact loads are discussed. The results are mainly characterized by bending-shear failure, meanwhile specimens can maintain an acceptable integrity. More than 33% of the input impact energy is dissipated, which demonstrates its excellent impact resistance. As the impact height increases, the flexural cracks and shear cracks observed on the surface of specimens were denser and wider. The recorded time-history of impact force and mid-span displacement confirmed the three stages of relative movement between the hammer and the column. Additionally, the displacements had a notable delay compared to the rapid changes observed in the measured impact load. The deflection of the mid-span did not exceed 5.90mm while the impact load reached peak value. The impact resistance of the specimen can be improved by proper design for stirrup ratios and increasing the axial load. However, the cracking and spalling of the concrete cover at the impact point was obvious with the increasing in stiffness.
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