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      • Off-Label Application of Pipeline Embolization Device for Intracranial Aneurysms

        Liang Buqing,Lesley Walter S.,Robinson Timothy M.,Chen Wencong,Benardete Ethan A.,Huang Jason H. 대한신경중재치료의학회 2019 Neurointervention Vol.14 No.2

        Purpose: The Pipeline embolization device (PED) is approved in the USA for treating giant and large aneurysms arising from the petrous to superior hypophyseal segments of the internal carotid artery in patients older than 21 years of age. This study investigates off-label PED results in a large cohort. Materials and Methods: Retrospective, single-center review of all patients who had off-label PED surgery. Results: Sixty-two aneurysms (48 patients) underwent off-label PED treatment from 2012–2017. There were 44 females and four males (age 21 to 75 years; mean/median, 54.3/55.0 years). The most common presenting symptom was headache (47/62, 75.8%). All aneurysms were in the anterior circulation. Aneurysm size ranged from 1.4 to 25.0 mm (mean/median, 7.6/6.9 mm). Fifty-two aneurysms had post-operative imaging with total/near-complete occlusion of 84.6% (44/52). Aneurysm-based operative near-term complication rate was 9.7% while there were no permanent complications. For aneurysms and headache, 86.7% improved/resolved after embo-surgery, and were four times more likely to have a better clinical outcome (resolved or improved symptoms) after surgery (odds ratio [OR], 4.333; P=0.0325). Left-sided aneurysms had a higher occlusion rate (OR, 20; P=0.0073). Hypertension (OR, 4.2; P=0.0332) and smoking (OR, 7; P=0.0155) were more prone towards aneurysm occlusion. Patients without a family history were 14 times more likely to have favorable imaging outcome (P=0.0405). There is no difference of occlusion rates between untreated and previously treated aneurysms (P=0.6894). Overall, occlusion rate decreased by 14% with an increase of aneurysm size by 1 mm (P=0.0283). Conclusion: For anterior circulation aneurysms, the off-label application of PED is as effective and safe as reported for on-label intracranial aneurysms.

      • Predicting Quality of Cloud Services for Selection

        Mingdong Tang,Wei Liang,Buqing Cao,Xiangyun Lin 보안공학연구지원센터 2015 International Journal of Grid and Distributed Comp Vol.8 No.4

        Predicting quality of services (QoS) is an important need when ranking cloud services for selection. QoS values of cloud services usually depend heavily on the user’s and service’s environments. Therefore, personalized QoS value prediction for cloud services is more desirable to users. Collaborative Filtering (CF) has recently been applied to personalized QoS prediction for services on the Web. However, seldom did they take the context information of service users and services into consideration. The following paper presents a CF-based method for predicting QoS values of cloud services. The method exploits not only the QoS information of users and services, but also one type of the most important context information of users and services, i.e., their geographic locations. Experiments conducted on a real dataset show that geographic location information is indeed helpful for improving the QoS prediction performance. The experimental results also demonstrate that the proposed method is significantly better than previous methods in prediction accuracy.

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        Mechanical Thrombectomy for Septic Embolism Secondary to Staphylococcus lugdunensis Bacteremia without Infective Endocarditis: A Case Report

        Nguyen Anthony Vinh Phuc,Daly Samuel Richard,Liang Buqing,Lesley Walter Scherbaum 대한신경중재치료의학회 2022 Neurointervention Vol.17 No.3

        A cerebral large vessel occlusion due to septic embolism with resultant stroke is a known complication of infective endocarditis and can cause severe neurologic disability. However, septic embolism rarely occurs in the absence of infective endocarditis, and emboli due to different organisms may behave differently. As such, it is important to recognize the different pathogens that can cause septic embolism resulting in cerebral large vessel occlusion and to have data on successful treatments. We describe here a case of mechanical thrombectomy for septic embolism secondary to <i>Staphylococcus lugdunensis</i> bacteremia without infective endocarditis.

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