Blood-Blister Aneurysms of the Internal Carotid Artery in Tibetan and Han Populations : A Retrospective Observational Study

Bowen Huang,Yanming Ren,Hao Liu,Anqi Xiao,Lunxin Liu,Hong Sun,Yi Liu,Hao Liu,Lu Ma,Chang-Wei Zhang,Chao-Hua Wang,Min He,Yuekang Zhang,Chao You,Jin Li 대한신경외과학회 2024 Journal of Korean neurosurgical society Vol.67 No.3

Objective : Blood-blister aneurysms (BBAs) of the internal carotid artery (ICA) are challenging lesions with high morbidity and mortality rates. Although research on BBAs is well documented in different populations, the study of BBAs in the Tibetan population is extremely rare. This study aimed to evaluate the characteristics of BBAs and analyze the treatment modalities and long-term outcomes in the Tibetan population in comparison with the Han population. Methods : The characteristics of patients with BBAs of the ICA from January 2009 to January 2021 at our institution were reviewed. The features of aneurysms, treatment modalities, complications, and follow-up outcomes were retrospectively analyzed. Results : A total of 130 patients (41 Tibetan and 89 Han patients) with BBAs of the ICA who underwent treatment were enrolled. Compared with the Han group, the Tibetan group significantly demonstrated a high ratio of BBAs among ICAs (8.6%, 41/477 vs. 1.6%, 89/5563; p<0.05), a high ratio of vasospasm (34.1%, 14/41 vs. 6.7%, 6/89; p=0.001), a high risk of ischemic events (43.9%, 18/41 vs. 22.5%, 20/89; p<0.05), and a low ratio of good outcomes (modified Rankin scale, 0–2) at the 1-year follow-up (51.2%, 21/41 vs. 74.2%, 66/89; p<0.05). The multivariate regression model showed that ischemic events significantly contributed to the prediction of outcomes at 1 year. Further analysis revealed that microsurgery and vasospasm were associated with ischemic events. Conclusion : In comparison with Han patients, the Tibetan population had a high ratio of BBA occurrence, a high incidence of ischemic events, and a high ratio of poor outcomes. The endovascular approach showed more benefits in BBA patients.

Digital Implementation of Optimal Phase Calculation for Buck-Boost LLC Converters

Qian, Qinsong,Ren, Bowen,Liu, Qi,Zhan, Chengwang,Sun, Weifeng The Korean Institute of Power Electronics 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6

Buck-Boost LLC (BBLLC) converters based on a PWM + phase control strategy are good candidates for high efficiency, high power density and wide input range applications. Nevertheless, they suffer from large computational complexity when it comes to calculating the optimal phase for ZVS of all the switches. In this paper, a method is proposed for a microcontroller unit (MCU) to calculate the optimal phase quickly and accurately. Firstly, a 2-D lookup table of the phase is established with an index of the input voltage and output current. Then, a bilinear interpolation method is applied to improve the accuracy. Meanwhile, simplification of the phase equation is presented to reduce the computational complexity. When compared with conventional curve-fitting and LUT methods, the proposed method makes the best tradeoff among the accuracy of the optimal phase, the computation time and the memory consumption of the MCU. Finally, A 350V-420V input, 24V/30A output experimental prototype is built to verify the proposed method. The efficiency can be improved by 1% when compared with the LUT method, and the computation time can be reduced by 13.5% when compared with the curve-fitting method.

Calculation of cavitation evolution and associated turbulent kinetic energy transport around a NACA66 hydrofoil

Xiaojun Li,Bowen Li,Benxu Yu,Yun Ren,Bo Chen 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.3

The physical mechanism of flow unsteadiness is one of the key problems in cavitating flow. Significant efforts have been exerted to explain the cavitation-vortex interaction mechanism. As well, the process of kinetic energy transport during the evolution of unsteady cavitating flow must be elucidated. In this work, 2D calculations of cavitating flow around a NACA66 hydrofoil were performed based on the open source software OpenFOAM. The modified shear stress transport k-ω turbulence model, which considers curvature and turbulent eddy viscosity corrections, was employed to close the governing equations. The Schnerr-Sauer cavitation model was adopted to capture the cavitation phase change process. Numerical results showed reasonable consistency with the results of the experiments conducted by Leroux et al. (2004). The results showed that cavitation promotes turbulence intensity and flow unsteadiness around the hydrofoil. During the attached sheet cavity growth stage, high-value regions of turbulent kinetic energy are located substantially at the interface of the cavity, particularly at the rear portion of the cavity region. During the cloud cavity shed-off stage, the cavity begins to break off and the maximum value of turbulent kinetic energy is observed inside the shed cavity. Finally, the influence of cavitation on the turbulence intensity is illustrated using the turbulent kinetic energy transport equation, which shows that the pressure diffusion and turbulent transport terms dominate as cavitation occurs. In addition, cavitation promotes turbulence production and increases dissipation with fluid viscosity and flow unsteadiness. The viscous transport term only acts in the cavitation shedding stage under large-scale vortex shedding. Overall, these findings are of considerable interest in engineering applications.

Digital Implementation of Optimal Phase Calculation for Buck-Boost LLC Converters

Qinsong Qian,Bowen Ren,Qi Liu,Chengwang Zhan,Weifeng Sun 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.6

Buck-Boost LLC (BBLLC) converters based on a PWM + phase control strategy are good candidates for high efficiency, high power density and wide input range applications. Nevertheless, they suffer from large computational complexity when it comes to calculating the optimal phase for ZVS of all the switches. In this paper, a method is proposed for a microcontroller unit (MCU) to calculate the optimal phase quickly and accurately. Firstly, a 2-D lookup table of the phase is established with an index of the input voltage and output current. Then, a bilinear interpolation method is applied to improve the accuracy. Meanwhile, simplification of the phase equation is presented to reduce the computational complexity. When compared with conventional curve-fitting and LUT methods, the proposed method makes the best tradeoff among the accuracy of the optimal phase, the computation time and the memory consumption of the MCU. Finally, A 350V-420V input, 24V/30A output experimental prototype is built to verify the proposed method. The efficiency can be improved by 1% when compared with the LUT method, and the computation time can be reduced by 13.5% when compared with the curve-fitting method.

An Accurate Small Signal Modeling and Control Loop Design of Active Clamp Flyback Converter

Shengyou Xu,Qinsong Qian,Bowen Ren,Qi Liu 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

An accurate small signal model of active clamp flyback (ACF) converter is proposed in this paper. To obtain a precise model, the ESR of output capacitor was considered. Different to traditional flyback converter, because of the resonant effect, at the three to five times of switching frequency, ACF converter was added two poles which result in high oscillation in frequency responses curve. To get sufficient phase margin and avoid resonant inductor oscillation affect, a fundamental error compensator was given to keep control loop stabled. Then a 65W prototype was implemented to verify the performance of the designed control loop, the simulation and experimental results showed that the adjusted process between different load status haven’t result in much voltage overshoot or undershoot and need a long regulate time.

Direct catalytic conversion of glucose and cellulose

Li, Zhenhuan,Su, Kunmei,Ren, Jun,Yang, Dongjiang,Cheng, Bowen,Kim, Chan Kyung,Yao, Xiangdong The Royal Society of Chemistry 2018 GREEN CHEMISTRY Vol.20 No.4

<P>Biomass product 5-hydroxymethylfurfural (5-HMF) can be used to synthesize a broad range of value added compounds currently derived from petroleum. Thus, the effective conversion of glucose or cellulose (the major components of biomass) into fuels and chemical commodities has been capturing increasing attention. Previous studies have been extensively focused on a two-step process for producing 5-HMF from glucose or cellulose, <I>i.e.</I>, the isomerization of glucose into fructose and then the dehydration of fructose. We herein discovered that heterogeneous sulfonated poly(phenylene sulfide) (SPPS) containing strong Brønsted acid sites is able to convert glucose and cellulose into 5-HMF with a high yield in ionic liquids (ILs). The optimal activity of glucose conversion to 5-HMF achieves a yield of 87.2% after 4 h reaction at 140 °C. For direct cellulose conversion, a 5-HMF yield of 68.2% can be achieved. The reaction mechanism over the SPPS catalyst in ILs was studied by DFT calculations, and the results indicated that the SO3H group of SPPS plays a crucial role in glucose conversion into 5-HMF, and it acts as a proton donor as a Brønsted acid and functions as a proton acceptor as the conjugate base. Furthermore, the anions and cations of ILs together with SO3H-SPPS helped in stabilizing the reaction intermediates and transition states, which also resulted in glucose facile conversion into 5-HMF. The new catalyst system highlights new opportunities offered by optimizing the production of 5-HMF directly from glucose and cellulose.</P>