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        Clinical Characteristics of Patients with Adrenal Insufficiency and Fever

        Jang Wooyoung,Sohn Youngseok,Park Jung Hwan,Pai Hyunjoo,Kim Dong Sun,Kim Bongyoung 대한의학회 2021 Journal of Korean medical science Vol.36 No.23

        Background: Because persistent fever often occurs in adrenal insufficiency, it might be confused with infectious diseases. This study aimed to identify clinical characteristics and risk factors of patients with adrenal insufficiency and fever. Methods: All adult patients (n = 150) admitted to a tertiary care hospital in South Korea and diagnosed with adrenal insufficiency between 1 March 2018, and 30 June 2019, were recruited. Patients were excluded if they had: 1) proven structural problems in the adrenal or pituitary gland; 2) a history of chemotherapy within 6 months prior to the diagnosis of adrenal insufficiency; and 3) other medical conditions that may cause fever. Results: Among the included patients, 45 (30.0%) had fever at the time of the diagnosis of adrenal insufficiency. The mean C-reactive protein level was higher (11.25 ± 8.54 vs. 4.36 ± 7.13 mg/dL) in patients with fever than in those without fever. A higher proportion of patients with fever changed antibiotics (33.3% vs. 1.0%). On multivariate logistic regression analysis, female sex (odds ratio [OR], 0.32) lowered the risk of adrenal insufficiency with fever, while a history of surgery within 6 months (OR, 4.35), general weakness (OR, 7.21), and cough (OR, 17.29) were significantly associated with that. Conclusion: The possibility of adrenal insufficiency should be considered in patients with fever of unknown origin, especially those with risk factors.

      • SCOPUSKCI등재

        열화처리에 따른 고무와 강선코드간 접착계면의 변화

        서곤,손봉영 ( Gon Seo,Bongyoung Sohn ) 한국공업화학회 1994 공업화학 Vol.5 No.4

        열화처리 후 고무와 황동이 피복된 강선코드의 접착계면 변화를 오제 광전자 분광기와 주사 전자현미경으로 조사하였다. 열열화 후에는 접착층의 부분 산화와 추가 성장이, 습윤열화 후에는 접착층과 황동의 부분 소실이, 동적열화 후에는 접착층의 파괴와 철심의 부식이 관찰되었다. 이러한 접착제면의 변화를 인장시험에서 측정된 접착 성질과 관련지어 고찰하였다. The changes in adhesion interface between rubber compound and brass plated steel cord after various aging treatments were studied by using an Auger electron spectrometer and a scanning electron microscope. After thermal aging, partial oxidation and additional growth of adhesion layer were observed. The adhesion layer and brass were partially removed after humid aging. With dynamic aging the adhesion layer was destroyed and the corrosion of steel core was proceeded. The changes in adhesion interface were discussed in terms of the adhesion properties determined from the stress-strain experiments.

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