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RISS 인기검색어
- 검색키워드
- 저자 : Bhutani, Kapil (검색결과 3 건)
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Synthesis and Biological Evaluation of Novel Substituted-Imidazolidine Derivatives
Husain, Asif,Bhutani, Rubina,Kumar, Deepak,Shin, Dong-Soo Korean Chemical Society 2013 대한화학회지 Vol.57 No.2
A series of newer substituted-imidazolidine derivatives 3a-k were synthesized and assayed in vivo to investigate their anti-inflammatory, analgesic and antiulcer activity. The results of biological evaluation revealed that the three compounds, 4-[1,3-bis(4-hydroxy-3-methoxybenzyl)-2-imidazolidinyl]phenyldiethylamine (3g), 4-[1,3-bis(3-Ethoxy-4-hydroxybenzyl)-2-imidazolidinyl] phenyldiethylamine (3h) and 4-(1,3-bis(benzo[d][1,3]dioxol-5-ylmethyl)-4-methylimidazolidin-2-yl)-N,N-diethylbenzenamine (3j) were good in their anti-inflammatory and analgesic actions. Additionally these derivatives showed superior GI safety profile as compared to that of the standard drug in terms of low severity index. The results are statistically treated for its significance.
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Kumar, Ashish,Singh, Abhinav,Bhutani, Kapil Techno-Press 2021 Advances in concrete construction Vol.12 No.5
In the era of building engineering the intensification of Self Compacting Concrete (SCC) is world-shattering magnetism. It has lot of rewards over ordinary concrete i.e., enrichment in production, cutback in manpower, brilliant retort to load and vibration along with improved durability. In the present study, the mechanical strength of CM-2 (SCC containing 10% of rice husk ash (RHA) as cement replacement and 600 grams of glass fibers per cubic meter) was investigated at various dosages of cement replacement by fly ash (FA) and GGBS. A total of 17 SCC mixtures including two control SCC mixtures (CM-1 and CM-2) were developed for investigating fresh and hardened properties in which, ten ternary cementitious blends of SCC by blending OPC+RHA+FA, OPC+RHA+GGBS and five quaternary cementitious blends (OPC+RHA+FA+GGBS) at different replacement dosages of FA and GGBS were developed with reference to CM-2. For constant water-cement ratio (0.42) and dosage of SP (2.5%), the addition of glass fibers (600 grams/m<sup>3</sup>) in CM-1 i.e., CM-2 shows lower workability but higher mechanical strength. While fly ash based ternary blends (OPC+RHA+FA) show better workability but lower mechanical strength as FA content increases in comparison to GGBS based ternary blends (OPC+RHA+GGBS) on increasing GGBS content. The pattern for mixtures appeared to exhibit higher workablity as that of the concentration of FA+GGBS rises in quaternary blends (OPC+RHA+FA+GGBS). A decrease in compressive strength at 7-days was noticed with an increase in the percentage of FA and GGBS as cement replacement in ternary and quaternary blended mixtures with respect to CM-2. The highest 28-days compressive strength (41.92 MPa) was observed for mix QM-3 and the lowest (33.18 MPa) for mix QM-5.
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Amitoj Singh,Bakshish Singh,Bhupesh Grover,Gautam Bhutani,Aniket Sharma 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.6
General incidents happening ongoing in trains nowadays happen due instant fire in railways because of multiple reasons resulting in health hazards and even deaths. This paper provides a remedy to reduce the losses of life occurring due to fire accidents in trains. In the past few years Indian railways has witnessed various forms of train accidents in which catching of fire is of serious concern. Fire on running bogie is severely dangerous than the stationary ones. The damage is severe because of lack of alertness and lack of communication which leads to the time delay in action. This project provides automation to the trains by applying automatic brakes and along with the ventilation in case of fire and smoke detection. The railway staff and passengers need to take all possible precautions in order to avoid any of the above mistakes so as to minimize the possibility of fire break out. The project consists of thermistor gas sensor, buzzer, fans, pneumatic actuators, solenoid pneumatic valve. Whenever the fire is detected with the help of fire sensors, thermistor and a safety circuit sends signal to solenoid valve and triggers the brakes and allows exhaust fans for proper air flow in and out of a chamber to avoid suffocation and it also starts the alarm to alert the authorities.
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