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Piyush Aggarwal,Anwin Joseph Kavanal,Harmandeep Singh,Rajender Kumar,Rajeev Ranjan,Jitupam Baishya,Anish Bhattacharya 대한핵의학회 2021 핵의학 분자영상 Vol.55 No.6
Hodgkin’s lymphoma most commonly presents as painless lymphadenopathy and systemic B symptoms like fever, nightsweats, and weight loss. But rarely, it can present with unusual paraneoplastic manifestations. In the present case, we reporta 30-year-old woman who presented with sub-acute onset pan-cerebellar symptoms. The serum neuronal antibody panel wasnegative. She underwent F-18 FDG PET/CT to evaluate the neoplastic etiology as the underlying cause, which demonstratedboth the primary etiology and the paraneoplastic changes in the brain.
Piyush Aggarwal,Anupriya Anwariya,Anwin Joseph Kavanal,Ashwani Sood,Santosh Ranjan Jena,Bhagwant Rai Mittal 대한핵의학회 2023 핵의학 분자영상 Vol.57 No.3
Peptide receptor radionuclide therapy (PRRT) has become an established treatment for patients with inoperable and/ormetastatic, well-differentiated neuroendocrine tumors with overexpression of somatostatin receptor type 2 (SSTR-2). Thepost-therapy 177Lu-DOTATATE whole-body scan not only assesses the biodistribution of the lesions seen on pre-therapy68 Ga-SSTR PET/CT scan but also provides a quick assessment of disease status and dosimetry during treatment. Like anyother radionuclide scan, the whole-body 177Lu-DOTATATE scan may also show abnormal radiotracer uptake, which mayrequire further imaging to establish its exact etiology. Though radiotracer emboli mimicking focal pulmonary lesions havebeen described with 18F-FDG and 68 Ga-DOTANOC PET/CT scans, similar artifacts with post-therapy 177Lu-DOTATATEscans have not been described. Herein, we report two cases of hot emboli in the post-therapy 177Lu-DOTATATE scans.
Kunal Ramesh Chandekar,Sindhu Tanigassalam,Anwin Joseph Kavanal,Singh Harmandeep,Anish Bhattacharya,Ravimohan Suryanarayan Mavuduru 대한핵의학회 2022 핵의학 분자영상 Vol.56 No.2
The rapidly evolving clinical utility of prostate-specific membrane antigen (PSMA) PET/CT as an imaging modality for prostate cancer (PCa) has brought to the forefront a multitude of non-prostatic diseases also exhibiting PSMA radioligand uptake. We report a case of a 71-year-old male with PCa who underwent PSMA PET/CT for recurrence evaluation. The scan demonstrated [68 Ga]Ga-PSMA-11 uptake in the distal ileum. Retrospective enquiry revealed that the patient was a known case of Crohn’s disease. This case highlights an uncommon finding of PSMA radioligand uptake in the distal small bowel (non-prostatic benign pathological uptake) in a patient with known Crohn’s disease, which may be misinterpreted in the evaluation of PCa.