http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Impact of the COVID-19 Pandemic on Adherence to Denosumab Therapy: A Single Center Study
Kobayashi Kazuyoshi,Sato Koji,Ando Toshihiro,Ando Kei,Imura Saori 대한척추외과학회 2023 Asian Spine Journal Vol.17 No.5
Study Design: A retrospective comparative study of denosumab therapy adherence before and during the coronavirus disease 2019 (COVID-19) pandemic.Purpose: To evaluate the effect of the COVID-19 pandemic on denosumab therapy adherence in Japan.Overview of Literature: Denosumab is a monoclonal antibody for osteoporosis treatment. Delayed denosumab injections are associated with reduced treatment responses, which was a concern during the COVID-19 pandemic.Methods: Participants included 376 patients who received denosumab (60 mg every 6 months) from January 2013 to June 2021. The time from therapy initiation to discontinuation was used to measure persistence, and that between initial and subsequent injections was used to determine adherence. The pandemic period was from March 2020 to December 2021.Results: Patients were divided into those treated after March 2020 (pandemic group, n=244) and those who discontinued treatment before March 2020 (non-pandemic group, n=132). Non-persistent cases accounted for 154, including 24 (20%), 64 (19%), and 66 (53%) aged ≤59 years, 60–79 years, and ≥80 years, respectively. The overall persistence rate at 78 months was 59.2%. Postponed cases were significantly lower in the non-pandemic group than in the pandemic group (8% vs. 15%, <i>p</i> =0.042). Postponement with a delay of 1–2 months did not significantly differ between the two groups, but with a significant difference for a delay of ≥3 months (0% vs. 36%, <i>p</i> =0.024).Conclusions: Denosumab adherence remained constant but postponed cases significantly increased during the COVID-19 pandemic. Better communication by health providers on denosumab adherence and alternative administration may reduce dosing interruptions in similar pandemic situations.
Cathodoluminescence spectroscopic study of the boron-nitrogen co-doping diamond films
Yuko Hatanaka,Sadao Takeuchi,Koji Iwasaki,Hidenori Gamo,Kiyoharu Nakagawa,Toshihiro Ando,Mikka Nishitani-Gamo 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
Co-doping diamond is of scientific and technologically interest because a new electrical and/or optical property is expected to obtain. In this study, we have carried out a simultaneous addition of diborane and nitrogen in the gas phase for the growth of co-doping diamonds by microwave plasma-assisted chemical vapor deposition (MPCVD) method. We measured the cathodoluminescence (CL) spectra of the co-doping diamond films. To investigate the effect of boron-nitrogen co-doping addition on the CL spectra, we compared the CL spectra of boron-nitrogen co-doping diamonds with those of nitrogen-doped diamonds. The results revealed that the addition of boron suppressed the nitrogen incorporation into the CVD diamonds.
Catalytic synthesis of the ZnO-carbon nanofilament composite for sensor applications
Minoru Kuwata,Koji Iwasaki,Hidenori Gamo,Kiyoharu Nakagawa,Toshihiro Ando,Mikka Nishitani-Gamo 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10
We have studied to synthesize a ZnO-carbon nanofilament composite (ZnO-CNF) as it is expected to yield an interesting properties for sensor applications. The ZnO-CNF is considered to have a large surface area and a high electrical conductivity. The ZnO-supported Co catalysts were used for the synthesis of the ZnO-CNF. In order to fabricate a pattern of the composite for a biosensor, we have tried to prepare a paste from the composite for a screen-printing. We found that Co loaded catalysts exhibited a high catalytic activity for the carbon yields. SEM observation revealed that fibriform carbon deposits were obtained on the surface of the ZnO powder. In the case of using the Co-loaded ZnO catalyst, we found that the diameter of the fibriform carbon nanomaterial depended on the C2H4 concentration in the reaction gas. The reaction conditions are important to control the diameter of the fibriform carbon nanomaterial. The ZnO-CNF paste consisted of the ZnO-CNF, ethyl cellulose, and 2-(2-Butoxyethoxy) ethanol was prepared. The line patterns having 150μm were successfully fabricated with using the paste by screen-printing method.