http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Alejandro León (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
Heavy and light monopoles in magnetic reversion in artificial spin ice
Alejandro León 한국물리학회 2013 Current Applied Physics Vol.13 No.9
This work makes a theoretical study of the dynamics of emergent elemental excitations in artificial spinice systems with hexagonal geometry during the magnetic reversion of the system. The magnetic andphysical parameters of the nanoislands that form the array are considered as variables in the study. Theparameters considered are: the energy barrier for the inversion of each nanoisland, the magneticmoment of the nanomagnets and the possible disorder in the sample. Our results show that thereversion dynamic presents two distinct mechanisms of magnetic reversion, with different elementalexcitations for each mechanism. The first mechanism presents a reversion with the appearance ofmagnetic monopoles that do not move in the samples (heavy monopoles) and the absence of Diracchains. In the other mechanism elemental magnetic excitations (light monopoles) appear that movegreat distances in the sample, giving rise to extensive Dirac chains during the magnetic reversion.
-
Aurelio Romero-Castro,Ismael León-Rivera,Laura Citlalli Ávila-Rojas,Gabriel Navarrete-Vázquez,Alejandro Nieto-Rodríguez 대한약학회 2011 Archives of Pharmacal Research Vol.34 No.2
In this study we report the synthesis and preliminary evaluation of a series of six 2-aryl-5(6)-nitro-1H-benzimidazole derivatives (1-6) as potential anticancer agents. Cytotoxicity was evaluated against seven human neoplastic cell lines using the MTT assay. Compound 6 [2-(4-chloro-3-nitrophenyl)-5(6)-nitro-1H-benzimidazole] was the most active of the series, showing an IC_50 of 28 nM against the A549 cell line. This compound displayed a selective in vitro cytotoxic activity index (>700) in non neoplastic HACAT cells (IC_50 = 22.2 μM). Compounds 3 and 6 induce arrest in the S phase of the cell cycle, and compounds 1-6 induce apoptosis in the K562 cell line. Compound 6 induces poly (ADP-ribose) polymerase (PARP) inhibition activity as a potential mechanism of action. These results suggest that compound 6 could be a potent anticancer agent. Compound 3 displayed the best inhibitory activity against PARP with an IC_50 value of 0.05 μM, compared to the activity shown by the positive control 3-aminobenzamide (IC_50 = 28.5 μM).
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
