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        Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)

        Shibuya, Akira,Nakahashi-Oda, Chigusa,Tahara-Hanaoka, Satoko The Korean Association of Immunobiologists 2009 Immune Network Vol.9 No.2

        Activating and inhibitory cell surface receptors play important roles in regulation of immune responses. Recent progress has demonstrated that many inhibitory receptors pair with activating, as well as inhibitory, isoforms, both of whose genes are located in small clusters on a chromosome. We and others identified paired activating and inhibitory immunoglobulin-like receptors, designated myeloid-associated immunoglobulin-like receptors (MAIR) (CD300). MAIR is a multigene family consisting of nine genes on a small segment of mouse chromosome 11. MAIR family receptors are preferentially expressed on myeloid cells, including macrophages, dendritic cells, granulocytes, and bone-marrow-derived cultured mast cells, and a subset of B cells and regulate activation of these cells. Thus, MAIR plays an important role in innate immunity mediated by myeloid cells.

      • KCI등재

        Oxygen Annealing Effects in Natural-Superlattice-Structured Ferroelectric Bi$_4$Ti$_3$O$_{12}$-SrBi$_4$Ti$_4$O$_{15}$ Thin Films

        Akira Shibuya,Masanori Okuyama,Minoru Noda 한국물리학회 2003 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.42 No.IV

        Bi4Ti3O12-SrBi4Ti4O15 thin lms have been prepared on Pt/Ti/SiO2/Si by pulsed laser deposition (PLD) and their crystalline and electrical properties have been characterized. After oxygen annealing, X-ray diraction (XRD) patterns and grain sizes in atomic force microscopy (AFM) images did not change very much. But P-E hysteresis loop measured at 60 Hz has been improved very much after oxygen annealing. The values of 2Pr and 2Ec were 32 C/cm2 and 190 kV/cm, respectively, after oxygen annealing while 2Pr and 2Ec were 20 C/cm2 and 145 kV/cm, respectively, before oxygen annealing. C-V hysteresis loops shows reasonable results compared with P-E hysteresis loops both before and after oxygen annealing. The relative dielectric constant and dielectric loss were 433 and 0.037, respectively, after oxygen annealing while 595 and 0.071 before post annealing. The dielectric constant of BIT-SBTi lm approaches to that of the ceramics which is around 100 at room temperature after oxygen annealing. This improvement of ferroelectrics is mainly attributed to reduction of oxygen vacancies.p탾

      • KCI등재

        Regulation of Immune Responses by the Activating and Inhibitory Myeloid-Associate Immunoglobuline-Like Receptors (MAIR) (CD300)

        Akira Shibuya,Chigusa Nakahashi-Oda,Satoko Tahara-Hanaoka 대한면역학회 2009 Immune Network Vol.9 No.2

        Activating and inhibitory cell surface receptors play important roles in regulation of immune responses. Recent progress has demonstrated that many inhibitory receptors pair with activating, as well as inhibitory, isoforms, both of whose genes are located in small clusters on a chromosome. We and others identified paired activating and inhibitory immunoglobulin- like receptors, designated myeloid-associated immunoglobulin-like receptors (MAIR) (CD300). MAIR is a multigene family consisting of nine genes on a small segment of mouse chromosome 11. MAIR family receptors are preferentially expressed on myeloid cells, including macrophages, dendritic cells, granulocytes, and bone-marrow-derived cultured mast cells, and a subset of B cells and regulate activation of these cells. Thus, MAIR plays an important role in innate immunity mediated by myeloid cells. Activating and inhibitory cell surface receptors play important roles in regulation of immune responses. Recent progress has demonstrated that many inhibitory receptors pair with activating, as well as inhibitory, isoforms, both of whose genes are located in small clusters on a chromosome. We and others identified paired activating and inhibitory immunoglobulin- like receptors, designated myeloid-associated immunoglobulin-like receptors (MAIR) (CD300). MAIR is a multigene family consisting of nine genes on a small segment of mouse chromosome 11. MAIR family receptors are preferentially expressed on myeloid cells, including macrophages, dendritic cells, granulocytes, and bone-marrow-derived cultured mast cells, and a subset of B cells and regulate activation of these cells. Thus, MAIR plays an important role in innate immunity mediated by myeloid cells.

      • KCI등재

        Observation of disossiative recombination in the hydrogen sheet plasma

        akira Tonegawa,Hiroie MATSUMOTO,Hiroyuki YAZAWA,Kazutaka KAWAMURA,Masataka ONO,Takehisa SHIBUYA 한국물리학회 2006 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.49 No.III

        The experimental observation of dissociative recombination in Molecular Assisted Recombination (MAR) for hydrogen detached plasma has been studied in the linear divertor plasma simulator, TPD-SheetIV. Measurements of the relative concentrations of atomic and molecular ions (nH+, n+ H2, and n+ H3), electron density (ne), electron temperature (Te), and heat load to the target plate (Q) were carried out in hydrogen detached plasma with hydrogen gas puff at varying discharge current. An “omegatron” mass analyzer, situated behind a small hole of the endplate, is used for analyzing ion species. It is shown from these results that the dominant molecular process is a dissociative recombination process via H+ 2 , H+ 3 in the plasma over the range of low plasma density (<5 × 1018 m.3) and low hydrogen pressure (<4 mTorr). In contrast, molecular assisted dissociation (MAD) always dominates over the MAR in the high density plasma (>5 × 1018 m.3).

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