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        Ethnobotanical importance of the endemic taxa in the Egyptian flora

        El-Khalafy Mohamed Mahmoud,Ahmed Dalia Abd El-Azeem,Shaltout Kamal Hussein,Haroun Soliman Abdelfattah,Al-Sodany Yassin Mohamed 한국생태학회 2023 Journal of Ecology and Environment Vol.47 No.3

        Background: Endemic species are important components in the flora of most world regions. Most of these species have become threatened and exposed to extinction within the last few years. The present study aims to evaluate the ecosystem services offered by the endemic plant taxa in Egypt and the threats that affect them. Twenty-five field visits were conducted during summer 2018 to spring 2022 to several locations all over Egypt. In each location, the main habitats, national distribution, abundance, goods and threats were recorded. Results: Egypt has 41 endemic taxa belonging to 36 genera and 20 families inhabiting 10 main habitats. Rocky surfaces and sandy formations have the highest number of endemic species. The relation between the number of endemic taxa and the abundance categories indicated that 2 taxa are rare (4.9% of the total taxa), while the remaining were very rare (95%). The most represented offered good was the medicinal uses (32 taxa = 78%), while fuel plants were only represented by 2 taxa (2 taxa = 4.9%). Besides, 14 taxa (34.1% of the total studied taxa) have at least 1 environmental service. Soil fertility (7 taxa = 50%) was the most represented, followed by sand accumulations (6 taxa out of 14 taxa = 43%), while shading plant was the least (1 taxon = 7.1%) (Rosa arabica). The most represented threat is over-cutting and over-collecting (38 taxa = 92.7%), while mining and quarrying is the least represented (4 taxa = 9.8%). Conclusions: The potential and actual goods, services and threats of the endemic taxa were assessed as follows; field observation, information collected from local inhabitants and herbalists, and a literature review. The present study recommended planning a strategy about the importance, threats and conservation of endemic taxa in Egypt that would help in the protection and rescue of these plants and increase awareness about the importance of these plants.

      • KCI등재

        Preparation of Polyurethane Silicon Oxide Nanomaterials as a Binder in Leather Finishing

        Hamed Elsayed,Rasha Attia,Ola Mohamed,Ahmed Haroun,Nabil El-Sayed 한국섬유공학회 2018 Fibers and polymers Vol.19 No.4

        Leather finishing processes using toxic organic solvent based produce volatile organic compounds (VOC), chronic exposure to this chemicals effect on workers' health causing many diseases especially lung cancer. So, polyurethane waterbased was synthesized for application in leather finishing instead of organic solvent based because it’s economic and safety for industry and workers. Preparation of water-based polyurethane (PU) depends on the reaction of polyethylene glycol (PEG, 300) with isophorone diisocyanate (IPDI) and the reaction of IPDI-1,4-butanediol (BDO) together with dimethylolpropionic acid (DMPA), was synthesized by poly-addition polymerization reaction. PU was then modified with different amounts of silicon dioxide nanoparticles (1-5 % SiO2), used as a binder in leather finishing. Leather coated was characterized physically, chemically and thermally by FTIR, GPC, DLS, TEM, SEM and TGA. The results revel that, water vapor permeability (WVP) of leather coated with PU modified with SiO2 showed improvement due to the existence of SiO2 particles which increases the interspaces of the polyurethane coating. SEM showed that when the amount of SiO2 nanoparticles increases, there is uniform nanoparticles accumulated can be observed. EDX prove the presence of Si and O2 elements and the formation of SiO2 nanoparticles. Mechanical properties discussed that tensile strength; tear strength and elongation at break % increase with increase SiO2 concentration until 3 % SiO2 nanoparticles. TGA showed an improvement of thermal stability of coated leather modified with SiO2. Therefore, this study succeeded in preparation of safe, ecofriendly of water-based polyurethane binders which modified with SiO2 for using in leather finishing.

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        Biochemical and histopathological studies of sulfonylurea derivative as a new chemotherapeutic agent against liver cancer in free‑ and nano‑coated forms

        Sroor Farid M.,Basyouni Wahid M.,Aly Hanan F.,Younis Eman A.,Mahrous Karima F.,Haroun Ahmed A. 한국응용생명화학회 2022 Applied Biological Chemistry (Appl Biol Chem) Vol.65 No.6

        The most frequent type of primary liver cancer is hepatocellular carcinoma (HCC), accounting for approximately 90% of primary liver cancers and a third leading cause of cancer deaths. In the current study, the synthesized compound 3 was re-formulated using tetraethyl orthosilicate (TEOS) with weight ratio (1:1) via sol-gel technique. The prepared material has been examined using Fourier transform infrared spectroscopy (FTIR), energy dispersive X-ray elemental analysis (EDX), and scanning and transmission electron microscopes (SEM and TEM). Herein, we investigate the mode of action of 3 as potent anti-liver cancer in vivo as normal and nano-forms. Rats were given a single dosage of 50 mg/kg b.wt. of HCC through an intraperitoneal injection (ip). A single dosage of CCl4 (2 ml/kg IP) was also given to rats 2 weeks later. Several liver, tumor and oxidative stress biomarkers were detected including liver enzymes; alanine and aspartate aminotransferases (ALT and AST), alkaline phosphatse (ALP), gamma glutamyl transferase (GGT), glutathione (GSH), lipid peroxide (MDA), catalase (CAT), superoxide dismutase (SOD), total antioxidant capacity (TAC), α-fetoprotein and α-L-Fucosidase. Hepatic pathological pictures were also performed for the documentation of the presence of HCC and supported the biochemical results. Moreover, the DNA damage in liver tissues of male rats using comet assay was studied. The results showed that the HePG2 (− ve) group of rats exhibited a significant reduction (P < 0.05) in DNA damage values (9.30 ± 0.89) relative to other treatment groups. Nevertheless, the DNA damage values in the HePG2 (+ ve) and 5-flurouracil groups were significantly higher (P < 0.01) compared to the HePG2 (− ve) group. Additionally, HePG2 (coated 3) and HePG2 (3) groups exhibited significant decrease in the DNA damage compared to those in HePG2 (+ ve) group.

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