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박상균,이병철,이춘희,김문중,장봉열,한기옥,허기석 대한내과학회 1990 대한내과학회지 Vol.39 No.1
Thrombocytopenia with decreased megakaryocytes is a rare disorder characterized by thrombocytopenia due to a total absence or a marked reduction in the number of bone marrow megkaryocytes. We experienced a case of thrombocytopenia with decreased megakaryocytes in a 15-year-old girl, who was admitted with chief complaints of epistaxis and purpura on the lower extremities. There was a marked decrease of megakaryocytes in the marrow, and only minimal changes in other hematopoietic cell lines were seen. Follow-up studies, including bone marrow aspiration and biopsy which were performed eight months later, revealed typical features of aplastic anemia.