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차해연(Haiyan Che),트루옹넉투엔(Ngoc Tuyen Truong),김현표(Hyun Pyo Kim),박해일(Haeil Park) 대한약학회 2011 약학회지 Vol.55 No.6
Chrysin analogs with 2-heteroaryl groups were synthesized and evaluated for their inhibitory activities against PGE2 and NO production from LPS-induced RAW 264.7 cells. Chrysin analogs were synthesized from 2-hydroxy-4,6- dimethoxy-acetophenone and heteroaryl aldehydes in 3 steps. The tested chrysin analogs showed decreased inhibitory activity against PGE2 and NO production than those of chrysin.