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김기우(Ki Woo Kim),최지영(Ji Young Choi),목차수(Cha Soo Mok),신동진(Dong Jin Shin),최호천(Ho Cheon Choi),김경욱(Gyeong Wook Kim),최대섭(Dae Seop Choi) 대한내과학회 1989 대한내과학회지 Vol.36 No.4
N/A Multiple myeloma is a malignant disease charcterized by an abnormal proliferation of plasma cells. In 1847, Bence Jones first found paraprotein in urine, and Mclntyre described it in 1950. The frequencies of M-protein isotypes were followed by IgG, IgA, IgD, and IgE. Type D-myeloma occurs in less than 1 per cent of patients with multiple myeloma. It is male predominate and 90% of IgD multiple myelomas are type 1mbda and 10% are kappa, with most patients having Bence Jones proteinuria. The authors recently experienced a case of IgD multiple myeloma with lambda light chain which developed in a woman.
급성신우신염에서 99mTc - DMSA 신장스캔의 임상적 의의
이강욱(Gang Wook Yi),신동진(Dong Jin Shin),목차수(Cha Soo Mok),최대섭(Dae Seop Choi),최호천(Ho Cheon Choi),김경욱(Gyeong Wook Kim) 대한핵의학회 1989 핵의학 분자영상 Vol.23 No.2
N/A Patients with acute pyleonephritis may present with a spectrum of clinical symptoms and signs. There are few noninvasive diagnostic studies, however to confirm or exclude this diagnosis. To evaluate the clinical utility of 99mTc-DMSA renal scan in diagnosis of acute pyelonephritis, we performed 99mTc-DMSA renal scan in 37 patients suspected with urinary truct infection. Simultaneously kidney ultrasonography was done in 21 patients diagnosed with acute pyelonephritis, clinically. And we performed the followup scan after treatment in two to six weeks. The results were as follows. 1) 99mTc-DMSA renal scan disclosed single of multiple cortical defects and decreased radiouptake ratio of affected kidney in 23 patients among 25 patients diagnosed with acute pyleonephritis. 2) In the 21 patients with acute pyelonephritis, kidney ultrasonography showed abnormal findings in the 7 patients. And 99mTc-DMSA renal scan disclosed abnormal cortical defects in this 7 patients also. 3) Between the patients with acute pyelonephritis and those with lower urinary tract infection, asymptomatic bacteriuria or pyuria, right-to-left radiouptake ratios (R/L ratio ) were significantly different(p<0.001). 4) In two to six weeks after antibiotic therapy, we performed followup 99mTc-DMSA renal scan for 5 patients among 25 acute pyelonephritis patients. And we have found the improvement of cortical defects and the right-to-left radiouptake ratio. In conclusion, we thought that 99mTc-DMSA renal scan should be useful in diagnosis of acute pyelonephritis and follow up examination.