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고산홍경천 에탄올 추출물의 항산화작용과 쥐의 혈압 및 골격근 수축성에 미치는 영향
김은철(Yinzhe Jin),청위동(Yu-dong Cheng),이광진(Kwang Jin Lee),정용안(Yong An Jung),노경호(Kyung Ho Row) 한국생물공학회 2011 KSBB Journal Vol.26 No.3
To study the effects of ethanol extract of the Rhodiola Sachalinensis on the anti-oxidation and blood pressure and skeletal muscles contractility in rats. The ethanol extracts and fractions of Rhodiola Sachalinensis were determinated the anti-oxidation effects by DPPH (1,1-dipenyl- 2-picrylhydrazyl) method and comparing with the BHA (Butylated hydroxyanisole) and AA (Ascorbic acid). The gastrocnemius and soleus muscle contractility were observed by stmulating the sciatic nerve with electricity after affusing stomach with ethanol extract of the 200 mg/kg dosage of Rhodiola Sachalinensis for 4 weeks. The ethanol extract of the Rhodiola Sachalinensis could shorten latent period, increase maximal contractive extent and time and relaxative time at the twitch and complete tetanus of gastrocnemius and soleus muscles. The ethanol extract of the Rhodiola Sachalinensis shows high anti-oxidation effect and can enhance skeletal muscles contractility in rats.