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      • KCI등재

        증례 : 호흡기 ; 낭성 섬유증 환자에서 발생한 Mycobacterium abscessus 폐질환 증례

        정호중 ( Ho Jung Jeong ),김정훈 ( Jung Hoon Kim ),유덕 ( Duck Hyun Ryu ),이지은 ( Ji Eun Lee ),전지은 ( Ji Eun Jun ),정숙현 ( Suk Hyeon Jeong ),고원중 ( Won Jung Koh ) 대한내과학회 2015 대한내과학회지 Vol.88 No.1

        CF는 CFTR 유전자의 돌연변이에 의해 발생하는 열성 유전질환으로, 호흡기분비물을 제거하는 능력의 저하로 기관지확장증이 발생하고, 이와 동반된 여러 원인균에 의해 만성적인 폐감염증이 발생한다. 최근 서양에서는 CF 환자에서NTM 폐질환의 발생이 증가하고 있다. CF는 국내에서는 매우 드문 유전질환으로, 저자들은 한국인 CF 환자에서 발생한 Mycobacterium abscessus 폐질환을 성공적으로 치료한 경험을 보고하는 바이다. Although cystic fibrosis (CF) is one of the most common hereditary disorders among Caucasians, it is very rare in the Koreanpopulation. Patients with CF are at particularly high risk for developing lung disease caused by nontuberculous mycobacteria suchas the Mycobacterium avium-intracellulare complex or Mycobacterium abscessus. Here, we report a successfully treated case of M. abscessus lung disease in a Korean patient with CF.

      • KCI등재

        혈액종양 : 다발성 전이를 동반한 설암 환자의 골격근전이와 β-HCG 상승 1예

        함준수 ( Jun Soo Ham ),황금빛 ( Keum Bit Hwang ),황수빈 ( Subin Hwang ),정숙현 ( Suk Hyeon Jeong ),이지윤 ( Ji Yun Lee ),이세훈 ( Se Hoon Lee ),박근칠 ( Keunchil Park ) 대한내과학회 2015 대한내과학회지 Vol.89 No.6

        Metastases to skeletal muscle and paraneoplastic syndromes involving β-human chorionic gonadotropin (HCG) production are an extremely rare manifestation of head and neck squamous cell carcinoma. We report a patient with a β-HCG-secreting squamous cell carcinoma of the tongue with diffuse metastases involving skeletal muscle. A 47 year old female, who was being treated heavily with palliative chemotherapy for metastatic tongue cancer, was admitted with a palpable thigh mass and pain. A magnetic resonance image showed an intramuscular metastasis in the thigh. Ultrasound-guided biopsy of the thigh mass confirmed metastatic squamous cell carcinoma. She was scheduled for enrollment into a clinical trial; however, a positive serum β-HCG test was noticed. There was no evidence of pregnancy or a trophoblastic or non-trophoblastic tumor secreting β-HCG. Finally, she was revealed to have a paraneoplastic syndrome with diffuse metastases and was ultimately referred for palliative care. We review the literature of previously reported cases of an increase of β-HCG in patients with head and neck cancer. (Korean J Med 2015;89:719-722)

      • 아동의 자기주도학습 특성에 관한 연구

        정숙 東亞大學校 學生生活硏究所 1999 學生硏究 Vol.27 No.-

        The purpose of this study was to know about personality characteristics of self-directed learning in children. Subjects in this study were 202 teachers who worked at Chinju, Sacheon City and so on. The scale was based factor of self-directed learning characteristics upon Guglielmino's SDLRS (Self-Directed Learning Readiness Scale). Self-directed learning sub-factors in children's included in scale were labeled ; openness to new learning opportunities, self-concept as an effective learner, initiative and independence in learning, informed acceptance responsibility for one's own learning, love of learning, creativity, ability to use basic study skills and problem-solving skills. The following conclusion were that self-directed learning sub-factors in children were constructed openness, self-concept, autonomous, self-assessment, internal-motivation and ability to problem-solving.

      • 자기주도학습력향상을 위한 수업모형 연구

        정숙,박영태 동아대학교 교육대학원 1999 동아교육논총 Vol.25 No.-

        It is very important for the learners to develop their ability to judge, select subjectively and learn information and knowledge necessary for themselves in the current open society towards learning. In this respect, for the development of this ability, school education must put a stress upon the premises that learners can prepare for the basis of learning for continuing education in the course of life and that they can develop the self-directed learning ability in order to think themselves and to search for a truth. Therefore, this study aims to develop instructional model so that the learners can improve a self-directed learning ability through school education. The questions for research are raised for a successful investigation as follows: First, what characteristics do the constituent factors of children have in their self-directed learning ability? Second, what is the concrete plan for the improvement of constituent factors in their selfdirected learning ability? Third, what is the integrated intructional model for the improvement of self-directed learning ability in children? The conclusions can be obtained in this study as follows: First, it can be proved that children have an ability in all the constituent factors of self-directed learning ability such as openness, self-concept, intrinsic motivation, autonomy, creativity, ability to problem-solving, self-evaluation and so on, but that their ability in specific constituent factors show lower than adults. Second, the individual teaching plans for the improvement of self-directed learning ability can include the establishment of purpose, preparation of conditions for learning, forning human relationship, supporting learning, the organization of learning group, proper homework, learning contract, the chances of the various experience and practice, self-evaluation, the role of teachers and so on. Third, the plans for the improvement of self-directed learning ability through analysis of study and instructional model which the improvement of children’s self-directed learning ability are meaningful learning matters, teacher’s activities, learning context, environment of learners, meaning creation of learners, learning contract. Fourth, the integrated instructional model for the improvement of self-directed learning ability consists of learners’ activities, and teachers’ activities are suggested in order to guide, promote and instruct learners’ activities. This is to put an emphasis upon the mutual cooperation between children and their teachers after due consideration into characteristic of children’s development during instruction. The activities of learners include the choice of subject for learning, meaning creation of learners, the establishment of concreate learning target self-evaluation, evaluation of comrade and self-reinforcement. The activities of teachers include preparation of conditions for learning based upon the various conditions of information, the choice of subject for learning and its suggestion, offering motive for learning creation, controlling members of group, evaluation of performance, and teachers’ reinforcement. Teaching by this integrated instructional model will enable children to develop their own ability of the specific constituent factors wanting, and this will promote elementary school children’s self-directed learning ability.

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